Pathogenicity of an Avian Influenza H9N2 Virus isolated From Broiler Chickens in Egypt

2016 ◽  
Vol 51 (2) ◽  
pp. 90
Author(s):  
Abdel HS ◽  
Ellakany HF ◽  
Hussien HA ◽  
ElBestawy AR ◽  
Abdel KM
Keyword(s):  
Avian Influenza ◽  
Broiler Chickens ◽  
H9n2 Virus ◽  
Avian Influenza H9n2

A Dose-Response Study of Inactivated Low Pathogenic Avian Influenza H9N2 Virus in Specific-Pathogen-Free and Commercial Broiler Chickens

2016 ◽  
Vol 60 (1s) ◽  
pp. 256-261 ◽  
Author(s):  
Walid H. Kilany ◽  
Ahmed Ali ◽  
Abdel-Hamid I. Bazid ◽  
Ayman H. El-Deeb ◽  
Mohamed A. Zain El-Abideen ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Dose Response ◽  
Broiler Chickens ◽  
H9n2 Virus ◽  
Specific Pathogen Free ◽  
Pathogenic Avian Influenza ◽  
Specific Pathogen ◽  
Commercial Broiler ◽  
Dose Response Study ◽  
Avian Influenza H9n2

scholarly journals Avian influenza H9N2 virus isolated from air samples in LPMs in Jiangxi, China

2017 ◽  
Vol 14 (1) ◽  
Author(s):  
Xiaoxu Zeng ◽  
Mingbin Liu ◽  
Heng Zhang ◽  
Jingwen Wu ◽  
Xiang Zhao ◽  
...  
Keyword(s):  
Avian Influenza ◽  
H9n2 Virus ◽  
Air Samples ◽  
Avian Influenza H9n2

scholarly journals Prevailing I292V PB2 mutation in avian influenza H9N2 virus increases viral polymerase function and attenuates IFN-β induction in human cells

2019 ◽  
Vol 100 (9) ◽  
pp. 1273-1281 ◽  
Author(s):  
Weihua Gao ◽  
Zhipeng Zu ◽  
Jiyu Liu ◽  
Jingwei Song ◽  
Xinyu Wang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Human Cells ◽  
H9n2 Virus ◽  
Viral Polymerase ◽  
Avian Influenza H9n2

scholarly journals The D253N Mutation in the Polymerase Basic 2 Gene in Avian Influenza (H9N2) Virus Contributes to the Pathogenesis of the Virus in Mammalian Hosts

2018 ◽  
Vol 33 (6) ◽  
pp. 531-537 ◽  
Author(s):  
Jinfeng Zhang ◽  
Rong Su ◽  
Xiaoyun Jian ◽  
Hongliang An ◽  
Ronbing Jiang ◽  
...  
Keyword(s):  
Avian Influenza ◽  
H9n2 Virus ◽  
Avian Influenza H9n2

scholarly journals Effects of Nigella sativa on immune responses and pathogenesis of avian influenza (H9N2) virus in turkeys

2016 ◽  
Vol 25 (1) ◽  
pp. 95 ◽  
Author(s):  
Sajid Umar ◽  
Abdul Rehman ◽  
Muhammad Younus ◽  
Qamar-un-Nisa ◽  
Asif Ali ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Immune Responses ◽  
Nigella Sativa ◽  
H9n2 Virus ◽  
Avian Influenza H9n2

scholarly journals Immunological and pathological adverse effects of avian influenza virus subtype H9N2 infection in aflatoxicated-broiler chickens

2020 ◽  
Vol 70 (4) ◽  
pp. 1889
Author(s):  
H.F. ELLAKANY ◽  
H.S. ABD-ELHAMID ◽  
L.A. TANTAWY ◽  
H.A. ELSAMADONY ◽  
A.R. ELBESTAWY ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Broiler Chickens ◽  
H9n2 Virus ◽  
Total Leukocyte Count ◽  
Cell Mediated Immunity ◽  
Hydropic Degeneration ◽  
Viral Shedding ◽  
Low Levels

Aflatoxin B1 (AFB1) is a metabolic product of the Aspergillus spp. of molds, which grow on several feedstuffs stored in hot moist conditions. It is one of the immunosuppressive agents that might influence the pathogenesisof avian influenza virus (AIV) subtype H9N2 in broilers, which can exacerbate the disease outcomes. The immunological, biochemical and pathological adverse health effects of an interaction between low levels of dietary aflatoxins (AFs) and H9N2 infection in broiler chickens were investigated. One hundred and eighty of unvaccinated 1-day-old COBB chicks were, therefore, raised for 35 days in the following treatment groups: control, AFs, AFs+H9N2, and H9N2. AFs in the basal diet was added at 200 ppb starting from the first day of age, while H9N2 virus was intra-nasally installed at a dose of 100 μl of 106 EID50/bird of allantois fluid at 23rd day. Humoral and cell-mediated immune responses were evaluated. Evidence of H9N2-AIV viral shedding was also detected. It has been observed that concurrent exposure of AFs and H9N2 virus negatively affected chicken performance traits i.e. lowered feed intake and body weights with exaggerated respiratory and digestive disturbances, and 20% mortality rate. Ten days’ post H9N2 infection, significant (p≤ 0.05) increment in serum transaminases (AST and ALT) and falling in cell-mediated immunity i.e. total leukocyte count, lymphocyte transformation activity and macrophage phagocytic activity were detected. Additionally, AFs+H9N2 significantly (p≤ 0.05) lowered H9N2-HI titers (5.5 Log2) than H9N2 alone (6.3 Log2). Pathologically, aflatoxicated chickens showed hydropic degeneration, hepatocytic vacuolation and necrosis of liver tissues with nephrosis and urates deposition in ureters, as well as bursal and thymic lesions, which were potent in H9N2–inoculated chickens. AFs exposure increased the incidence and titer of H9N2 viral shedding. It could be concluded that dietary contamination with AFs even at very low levels has explanatory effect in H9N2–inoculated broilers, and vice versa.

Aerosol Transmission of an Avian Influenza H9N2 Virus with a Tropism for the Respiratory Tract of Chickens

2013 ◽  
Vol 57 (3) ◽  
pp. 645-649 ◽  
Author(s):  
Jiewen Guan ◽  
Qigao Fu ◽  
Maria Chan ◽  
J. Lloyd Spencer
Keyword(s):  
Avian Influenza ◽  
Respiratory Tract ◽  
H9n2 Virus ◽  
Avian Influenza H9n2
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