A Review of the Endangered Medicinal Plant Blepharispermum subsessile DC: Its Chemistry, Pharmacology and Therapeutic Potential

2016 ◽  
Vol 23 (4) ◽  
pp. 191-194
Author(s):  
Pranati Nayak ◽  
Chinnamadasamy Kalidass
Keyword(s):  
Medicinal Plant ◽  
Skin Diseases ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Aerial Parts ◽  
Endangered Medicinal Plant ◽  
Whole Plant ◽  
Ethnomedicinal Uses ◽  
Spilarctia Obliqua

Blepharispermum subsessile DC. (Asteraceae) is a less explored folklore medicinal plant of India. It is found in the moist deciduous forests of Odisha, Madhya Pradesh, Chhattisgarh, Karnataka and Maharastra etc. It is locally known as Rasnajhadi in Odisha. The whole plant is used as Rasna, a potent Ayurvedic drug. Ethnomedicinally it is used for the treatment of diarrhea, skin diseases, eye troubles, backache and rheumatism, menstrual disorder, common cold and rhinitis. Reports suggest its use as a wormicidal and as tonic. The rhizome has an aromatic odour and is used in havan samagri. Its pharmacological activities include anti-microbial activity, oviposition deterent activity against potato tuber moth, anti-fertility, anti-implantation activity and anti-feedant activity against larvae of Spilarctia obliqua. Many different chromenes were isolated from the aerial parts and rhizomes of B. subsessile such as Desmethyl isoencecalin, 8-methoxy-2, 2-dimethyl chromene, desmethylisoencecalin, 5-hydroxy-6-acetyl-2-hydroxymethyl-2-methyl chromene and (-)-artemesinol. Besides chromenes the plant contains 1.2% essential oil, carvacrol, Ursolic acid acetate and β-sitosterol. The present work aims at presenting a comprehensive of the plant such as its botany, ethnomedicinal uses, chemical constituents, pharmacognostic and pharmacological uses. The information reported in this work contributes scientifically to recognizing the importance of Blepharispermum subsessile as a target in the search for new biotechnological investments.

scholarly journals Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities

Biomolecules ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1619
Author(s):  
Cornelia Fursenco ◽  
Tatiana Calalb ◽  
Livia Uncu ◽  
Mihaela Dinu ◽  
Robert Ancuceanu
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Inflammatory Agent ◽  
Aerial Parts ◽  
Solidago Virgaurea ◽  
Clinical Models ◽  
Potential Benefits ◽  
Anti Inflammatory ◽  
Ethnomedicinal Uses ◽  
Published Research

Solidago virgaurea L. (European goldenrod, Woundwort), Asteraceae, is a familiar medicinal plant in Europe and other parts of the world, widely used and among the most researched species from its genus. The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples. Its main chemical constituents are flavonoids (mainly derived from quercetin and kaempferol), C6-C1 and C6-C3 compounds, terpenes (mostly from the essential oil), and a large number of saponin molecules (mainly virgaureasaponins and solidagosaponins). Published research on its potential activities is critically reviewed here: antioxidant, anti-inflammatory, analgesic, spasmolitic, antihypertensive, diuretic, antibacterial, antifungal, antiparasite, cytotoxic and antitumor, antimutagenic, antiadipogenic, antidiabetic, cardioprotective, and antisenescence. The evidence concerning its potential benefits is mainly derived from non-clinical studies, some effects are rather modest, whereas others are more promising, but need more confirmation in both non-clinical models and clinical trials.

scholarly journals Imperata cylindrica: A Review of Phytochemistry, Pharmacology, and Industrial Applications

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1454
Author(s):  
Young-Kyung Jung ◽  
Dongyun Shin
Keyword(s):  
Medicinal Plant ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Industrial Applications ◽  
Imperata Cylindrica ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Pharmacological Studies

Imperata cylindrica is a medicinal plant native to southwestern Asia and the tropical and subtropical zones. To date, 72 chemical constituents have been isolated and identified from I. cylindrica Among these compounds, saponins, flavonoids, phenols, and glycosides are the major constituents. Investigations of pharmacological activities of I. cylindrica revealed that this edible medicinal herb exhibits a wide range of therapeutic potential including immunomodulatory, antibacterial, antitumor, anti-inflammatory, and liver protection activities both in vivo and in vitro. The purpose of this review is to provide an overview of I. cylindrica studies until 2019. This article also intends to review advances in the botanical, phytochemical, and pharmacological studies and industrial applications of I. cylindrica, which will provide a useful bibliography for further investigations and applications of I. cylindrica in medicines and foods.

Medicinal properties of Muntingia calabura L.: A Review

2021 ◽  
pp. 4509-4512
Author(s):  
Arif Nur Muhammad Ansori ◽  
Viol Dhea Kharisma ◽  
Tridiganita Intan Solikhah
Keyword(s):  
Medicinal Plants ◽  
Severe Acute Respiratory Syndrome ◽  
Medicinal Plant ◽  
Therapeutic Potential ◽  
Pharmacological Activities ◽  
Phytochemical Composition ◽  
Whole Plant ◽  
Novel Drugs ◽  
Medicinal Properties ◽  
Muntingia Calabura

Indonesia has abundant medicinal plants, which have been historically used by the population in treating diseases for generations. Traditional Indonesian medicine and the medicinal plants used could lead to the discovery of novel drugs. For example, Muntingia calabura L., also known as kersen, is a well-known medicinal plant that has been used to treat various diseases worldwide. The pharmacological activities and phytochemical composition of the whole plant of M. calabura L. have been investigated and identified by scientists in recent decades. These studies have established the therapeutic potential of kersen for drug discovery. This present review provides an overview of the ethnopharmacology, pharmacology, and phytochemistry of M. calabura L. as they relate to its use against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2).

scholarly journals Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities

2020 ◽  
Author(s):  
Cornelia Fursenco ◽  
Tatiana Calalb ◽  
Livia Uncu ◽  
Mihaela Dinu ◽  
Robert Ancuceanu
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Inflammatory Agent ◽  
Aerial Parts ◽  
The World ◽  
Solidago Virgaurea ◽  
Clinical Models ◽  
Potential Benefits ◽  
Ethnomedicinal Uses ◽  
Published Research

Solidago virgaurea L. (European goldenrod, Woundwort), Asteraceae, is a familiar medicinal plant in Europe and other parts of the world, widely used and among the most researched species from its genus. The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples. Its main chemical constituents are flavonoids (mainly derived from quercetin and kaempferol), C6-C1 and C6-C3 compounds, terpenes (mostly from the essential oil), and a large number of saponin molecules (mainly virgaureasaponins and solidagosaponins). Published research on its potential activities is critically reviewed here: antioxidant, antiinflammatory, analgesic, spasmolitic, antihypertensive, diuretic, antibacterial, antifungal, antiparasite, cytotoxic and antitumor, antimutagenic, antiadipogenic, antidiabetic, cardioprotective, and antisenescence. The evidence concerning its potential benefits is mainly derived from non-clinical studies, some effects are rather modest, whereas others are more promising, but need more confirmation in both non-clinical models and clinical trials.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

Chemical constituents, ethnomedicinal uses, pharmacology, and toxicity of Dysphania ambrosioides (L.) Mosyakin & Clemants, formerly Chenopodium ambrosioides L.

2021 ◽  
Vol 11 ◽  
Author(s):  
Boniface Pone Kamdem ◽  
Eutrophe Le Doux Kamto ◽  
Hugues Kamdem Paumo ◽  
Lebogang Maureen Katata-Seru ◽  
Dieudonné Emmanuel Pegnyemb ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chemical Constituents ◽  
Literature Information ◽  
Pharmacological Activities ◽  
In Vivo Experiments ◽  
Wide Range ◽  
Recent Developments ◽  
Available Information ◽  
Ethnomedicinal Uses

Background: Dysphania ambrosioides (L.) Mosyakin & Clemants is an aromatic herb native to South America, but also distributed widely throughout Africa and Europe. This plant is traditionally used to treat various ailments including, pain and swellings, flu, parasitic diseases, and as analgesic, antipyretic, and wound healing. Phytochemical analyses of D. ambrosioides revealed the presence of terpenoids, flavonoids, coumarins, fatty acids and miscellaneous compounds among others, which might be responsible for its modern pharmacological actions. Objective: The present work summarizes recent developments on phytochemistry, ethnomedicinal use, pharmacology, and toxicity of D. ambrosioides. A critical assessment of the literature information of D. ambrosioides is also presented. Methods: The available information on D. ambrosioides was collected through libraries and electronic databases [Scifinder, ACS, Scielo, Science direct, Pubmed (National Library of Medicine), Wiley, Springer, PROTA, Web of Science, Google Web, Yahoo search and Google scholar] from respective inception until january 2021. Results: More than 150 compounds, including terpenoids, flavonoids, coumarins, fatty acids, and miscellaneous compounds etc.. were identified from D. ambrosioides. D. ambrosioides exhibited a wide range of pharmacological activities, including antimalarial, anti-inflammatory, antiparasitic, anticancer, insecticidal, antigiardial, among others. Metal nanoparticles synthesized from D. ambrosioides extracts presented enhanced pharmacological activities as compared to the crude plant extracts counterparts. Conclusion: D. ambrosioides is a promising medicinal plant, however, more in vivo experiments, cytotoxicity tests, and mechanisms of actions of its extracts and compounds are recommended to transubstantiate the ethnomedicinal claims of this plant into scientific rationale-based information.

scholarly journals Phytochemical Profile and Biological Activity ofNelumbo nucifera

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Keshav Raj Paudel ◽  
Nisha Panth
Keyword(s):  
Traditional Medicine ◽  
Nutritional Value ◽  
Functional Foods ◽  
Skin Diseases ◽  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Tissue Inflammation ◽  
Whole Plant ◽  
Phytochemical Profile ◽  
Different Parts

Nelumbo nuciferaGaertn. (Nymphaeaceae) is a potential aquatic crop grown and consumed throughout Asia. All parts ofN. nuciferahave been used for various medicinal purposes in various systems of medicine including folk medicines, Ayurveda, Chinese traditional medicine, and oriental medicine. Many chemical constituents have been isolated till the date. However, the bioactive constituents of lotus are mainly alkaloids and flavonoids. Traditionally, the whole plant of lotus was used as astringent, emollient, and diuretic. It was used in the treatment of diarrhea, tissue inflammation, and homeostasis. The rhizome extract was used as antidiabetic and anti-inflammatory properties due to the presence of asteroidal triterpenoid. Leaves were used as an effective drug for hematemesis, epistaxis, hemoptysis, hematuria, and metrorrhagia. Flowers were used to treat diarrhea, cholera, fever, and hyperdipsia. In traditional medicine practice, seeds are used in the treatment of tissue inflammation, cancer and skin diseases, leprosy, and poison antidote. Embryo of lotus seeds is used in traditional Chinese medicine as Lian Zi Xin, which primarily helps to overcome nervous disorders, insomnia, and cardiovascular diseases (hypertension and arrhythmia). Nutritional value of lotus is as important as pharmaceutical value. These days’ different parts of lotus have been consumed as functional foods. Thus, lotus can be regarded as a potential nutraceutical source.

scholarly journals VALERIANA JATAMANSI: AN ETHNOBOTANICAL REVIEW

2018 ◽  
Vol 11 ◽  
Author(s):  
Afroz Patan
Keyword(s):  
Molecular Mechanism ◽  
Skin Diseases ◽  
Chemical Constituents ◽  
Modern Medicine ◽  
Therapeutic Use ◽  
Perennial Herb ◽  
Pharmacological Activities ◽  
Valeriana Jatamansi ◽  
The Family ◽  
Medicinal Properties

 Objective: The main objective of review is an effort to give detailed information on Valeriana jatamansi and its multiple medicinal properties. Methods: As per the literature, the plant V. jatamansi is a perennial herb and found at subtemperate Himalayan regions of the Kumaon and Garhwal. The plant most popularly known as “Valerian.” The plant belongs to the family Valerianaceae. The roots and rhizomes of the plants are traditionally used to treat ulcers, jaundice, dry cough, seminal weakness, skin diseases, leprosy, and for sleep enhancement due to the presence of a variety of different chemical constituents such as sesquiterpenes, coumarins, iridoids, lignanoids, alkaloids, and flavonoids. From literature, the reported methods performed for different pharmacological activities have been thoroughly discussed and complied. Results: Most of the studies compiled from literature shown that V. jatamansi possess antimicrobial, antioxidant, anti-inflammatory, cytotoxic, anxiolytic, and neuroprotective activities. Conclusion: The review reveals that continuous research on this plant is needed to know the exact molecular mechanism and further elaborative studies can lead to develop safe therapeutic use in modern medicine.

scholarly journals Chemical Constituents of Dichloromethane Extract of CultivatedSatureja khuzistanica

2007 ◽  
Vol 4 (1) ◽  
pp. 95-98 ◽  
Author(s):  
Firouz Matloubi Moghaddam ◽  
Mahdi Moridi Farimani ◽  
Sabah Salahvarzi ◽  
Gholamreza Amin
Keyword(s):  
Spectral Analysis ◽  
Medicinal Plant ◽  
Ursolic Acid ◽  
Chemical Constituents ◽  
Natural Occurrence ◽  
Aerial Parts

Four compounds β-sitosterol, β-sitosterol-3-O-β-d-glucopyranoside, ursolic acid and 4′,5,6-trihydroxy-3′, 7-dimethoxyflavone were characterized from the dichloromethane extract of the aerial parts ofSatureja khuzistanica(Lamiaceae), a native medicinal plant growing in Iran, on the basis of spectral analysis and comparing with the data in literature. The natural occurrence of these compounds can be conclusive for the chemotaxonomic characterization of the genusSatureja.

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