scholarly journals Urethral Catheterization: A Review of the Indications, Techniques, and Complications of Male Urethral Catheterization for General Medical Practice

2020 ◽  
Vol 2 (3) ◽  
pp. 66-74
Author(s):  
Adenike O Eketunde ◽  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Essential Role ◽  
Prostatic Hyperplasia ◽  
Urinary System ◽  
Routine Procedure ◽  
Urethral Catheterization ◽  
General Medical Practice ◽  
Alternative Measures ◽  
Prostatic Diseases ◽  
Catheterization Procedure

The physiologic process of micturition plays an essential role in the ability of the human body to regulate homeostasis. When the urinary system encounters an obstruction such as a foreign body within the bladder or other prostatic diseases like benign prostatic hyperplasia (BPH), alternative measures to drain the bladder is required, this birthed the use of urethral catheters & the catheterization procedure. Urethral catheterization dates to the early days of medicine and while it is mostly a routine procedure in this era, the total understanding of its indications, proper techniques, and associated complications remains an essential tool in the arsenal of a practicing physician.

scholarly journals The Etiology and Pathophysiology Genesis of Benign Prostatic Hyperplasia and Prostate Cancer: A New Perspective

Medicines ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 30
Author(s):  
Teow J. Phua
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Cell Biology ◽  
Cancer Biology ◽  
Cost Savings ◽  
Prostatic Hyperplasia ◽  
Biological Processes ◽  
New Perspective ◽  
Prostatic Diseases

Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown, with ageing being the greatness risk factor. Methods: This new perspective evaluates the available interdisciplinary evidence regarding prostate ageing in terms of the cell biology of regulation and homeostasis, which could explain the timeline of evolutionary cancer biology as degenerative, inflammatory and neoplasm progressions in these multifactorial and heterogeneous prostatic diseases. Results: This prostate ageing degeneration hypothesis encompasses the testosterone-vascular-inflamm-ageing triad, along with the cell biology regulation of amyloidosis and autophagy within an evolutionary tumorigenesis microenvironment. Conclusions: An understanding of these biological processes of prostate ageing can provide potential strategies for early prevention and could contribute to maintaining quality of life for the ageing individual along with substantial medical cost savings.

Underdetection of clinical benign prostatic hyperplasia in a general medical practice

1996 ◽  
Vol 11 (9) ◽  
pp. 513-518 ◽  
Author(s):  
Mary F. McNaughton Collins ◽  
Robert H. Friedman ◽  
Arlene Ash ◽  
Ruth Hall ◽  
Mark A. Moskowitz
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Medical Practice ◽  
Prostatic Hyperplasia ◽  
General Medical Practice

scholarly journals A Review on Serenoa serrulata: A Potential Medicinal Plant for Prostatic Diseases

2021 ◽  
Vol 3 (1) ◽  
pp. 19-33
Author(s):  
Jacqueline Aber ◽  
Bruhan Kaggwa ◽  
Hedmon Okella ◽  
Clement Olusoji Ajayi ◽  
Patrick Engeu Ogwang
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Adverse Effects ◽  
Medicinal Plant ◽  
Cucurbita Pepo ◽  
Prostatic Hyperplasia ◽  
Research Articles ◽  
Echinacea Angustifolia ◽  
Saw Palmetto ◽  
Prostatic Diseases

Background: Prostatic diseases which include prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer are the benign or malignant disorders that affect the prostate. Phytotherapies have been adopted as the alternative treatment/ management option especially for BPH since the current modern methods of treatment presents a lot of adverse effects. Methodology: The literature was searched using different databases including Medline/PubMed, Cochrane library, Scopus, Proquest library, Embase, EBooks and Google Scholar for relevant records for a period from 1988 to 2018 to identify all the published articles of S. serrulata regarding treatment of prostatic diseases. The key search terms were Serenoa serrulata, S. repens, Saw palmetto, Prostate cancer treatment with Serenoa serrulata, treatment of Benign Prostatic Hyperplasia with Serenoa serrulata,  phytochemicals of Serenoa serrulata, ethnobotanical uses of Serenoa serrulata, toxicity of Serenoa serrulata, pharmacological activities of Serenoa serrulata and also traditional management and treatment of prostatic diseases  using Serenoa serrulata and also clinical trials on treatment of prostatic diseases  with Serenoa serrulata. The retrieved articles were reviewed, synthesized and analyzed qualitatively. The reference list of the retrieved articles was also reviewed and synthesized. The original research articles which reported an investigation of S. serrulata of any study design, original published research articles, any time of publication and grey literature (conference papers, reported articles, academic thesis) were included. The articles whose full texts were not freely available by the time of search and those without clear information about methodology and study design were excluded. Results: This review reported that Serenoa serrulata belonging to the Arecaceae family commonly known as saw palmetto is used traditionally for treating prostatic disease conditions and other infertility conditions in both men and women. Phytochemical screening of hexanic and ethanolic extracts of S. serrulata comprised of free fatty acids and phytosterols which together contribute to their antiprostatic activities. These extracts of S. serrulata exhibited antiandrogenic, anti-inflammatory and anti-proliferative activities through inhibition of both isoenzymes 5α- reductase and inhibition of binding of dihydrotestosterone (DHT) to the cytosolic androgen receptors. This is a similar mechanism exhibited by finasteride and Tamsulosin both antiprostatic conventional drugs though the plant phytochemicals do not interfere with PSA secretion. S. serrulata has also been reported to be non-toxic in both non clinical and clinical trial studies. The medicinal plants reported by this review to be used in combination include; stinging nettle (Urtica dioca), Zingiber officinalis, Echinacea angustifolia and pumpkin (Cucurbita pepo). The antiprostatic conventional drugs reported include finasteride and Tamsulosin. Conclusion and Recommendation: The results showed that S. serrulata is effective in treating prostatic diseases. The potency and safety is improved when used in combination with Urtica dioca, Cucurbita pepo, Zingiber officinalis and Echinacea angustifolia as compared with anti-prostatic conventional drugs Finasteride and Tamsulosin alone. The plant combination has also been shown to have improvement in the quality of life and as well enhancing the synergy of Finasteride and Tamsulon and their adverse effects. Effective medicinal plant combinations should be formulated into products and integrated into the usual treatment for prostatic diseases.

Urethral bleeding as a presenting sign of benign prostatic hyperplasia in the dog: a retrospective study (1979-1993)

1995 ◽  
Vol 31 (3) ◽  
pp. 261-267 ◽  
Author(s):  
RA Read ◽  
S Bryden
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Blood Loss ◽  
Clinical Laboratory ◽  
Clinical Signs ◽  
Prostatic Hyperplasia ◽  
Prostatic Enlargement ◽  
Prostatic Diseases ◽  
Rectal Palpation ◽  
Antiandrogen Therapy ◽  
Veterinary Hospital

Nineteen dogs were presented to the Murdoch University Veterinary Hospital (MUVH) because of blood loss from the urethra, unassociated with other clinical signs of prostatic disease. Blood loss was intermittent in all cases, but was severe enough to require blood transfusion in one case. Prostatic enlargement was detected on rectal palpation in all cases, and benign prostatic hyperplasia was diagnosed after elimination of other prostatic diseases (i.e., infection, cysts, neoplasia) using diagnostic imaging and clinical laboratory tests. Castration resulted in cessation of blood loss; whereas antiandrogen therapy, an alternative treatment to castration, was less effective.

Phytoestrogen tissue levels in benign prostatic hyperplasia and prostate cancer and their association with prostatic diseases

Urology ◽  
2004 ◽  
Vol 64 (4) ◽  
pp. 707-711 ◽  
Author(s):  
Clemens BrÖssner ◽  
Karin Petritsch ◽  
Klaus Fink ◽  
Marco Auprich ◽  
Stephan Madersbacher ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Tissue Levels ◽  
Prostatic Diseases

scholarly journals Frequency and Trends of Prostatic Diseases in a Subset of Karachi Population: A Retrospective Study

2021 ◽  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
National Level ◽  
Prostatic Hyperplasia ◽  
P Value ◽  
Medical Sciences ◽  
Chi Square ◽  
Elderly Males ◽  
Chi Square Test ◽  
Prostatic Diseases ◽  
Basic Medical

Background: Prostatic diseases are a leading cause of frequent urinary complaints in elderly males. The most common diseases include prostatitis, benign prostatic hyperplasia, and prostate cancer. This study aimed to determine the frequency of the prostatic diseases, their trend over the years, and the association of age and diagnosis. Methods: A retrospective descriptive study was conducted in Basic Medical Sciences Institute (BMSI) at Jinnah Postgraduate Medical Centre, Karachi. Data was collected from the histopathological files and all the cases diagnosed from 2014 to 2018 were included. Statistical analysis was done using SPSS with 95% confidence interval and p-value of ≤ 0.05 was considered significant. The Chi-square test was applied to find the association with age and year of diagnosis. Results: Total 163 prostate cases were documented from 2014 to 2018, out of which 98 (60.1%) were of benign prostatic hyperplasia, which was most commonly diagnosed in men aged, 61-70. Prostatic adenocarcinomas having Gleason scores 8-10 were frequent and commonly seen in men aged 51-60 years. An increasing trend (p-value=0.053) was observed in the diagnosis of these prostatic diseases within these five years. Conclusion: Benign prostatic hyperplasia is the most frequently (p-value=0.140) diagnosed prostatic disease in men, followed by adenocarcinoma and prostatitis. Advanced stage prostatic adenocarcinoma was diagnosed more frequently 17(10.4%) and at an earlier age. There is an increase in the number (p-value=0.053) of cases of prostatic diseases diagnosed each year. National-level studies and health policies are needed to facilitate early diagnosis and treatment.

scholarly journals CD133 and CD166 as stem cell markers for predicting the possibility of developing prostatic cancer in cases of benign prostatic hyperplasia

2019 ◽  
Vol 12 (3) ◽  
pp. 1403-1416
Author(s):  
Khalida I. Noel ◽  
Mustafa M. Ibraheem ◽  
Basim S. Ahmed ◽  
Ahmed F. Hameed ◽  
Nibras H. Khamees ◽  
...  
Keyword(s):  
Stem Cell ◽  
Benign Prostatic Hyperplasia ◽  
Immunohistochemical Analysis ◽  
Prostatic Hyperplasia ◽  
Stem Cell Marker ◽  
Stem Cell Markers ◽  
Cell Marker ◽  
Over Expression ◽  
Prostatic Epithelium ◽  
Prostatic Diseases

Benign and malignant prostatic diseases are generally well-known in the world. Accordingly, this research is planned to assess the immunohistochemical analysis of CD133 and CD166 in the prostatic epithelium in samples of benign prostatic hyperplasia (BPH) and normal looking epithelium around prostatic adenocarcinoma samples (PCa) and to explore the opportunity of malignant alterations in benign tissue. The prostate samples were divided into 2 groups; 50 BPH samples, and 50 normally looking tissue surrounding prostatic carcinoma samples (NPCA). The samples were treated for immunohistochemical examination of CD133 and CD166. Over expression of CD133 appeared in the BPH group which was statistically significant as compared to NPCA group. Conversely, over expression of CD166 stem cell marker in NPCA group than BPH group as it was significant statistically. CD166 is a stem cell marker for tissue tumorigenicity, while the positive expression of CD133 is not of value for cancer initiation.

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