An evaluation of zinc, homocysteine, and vitamin D levels in adolescents with polycystic ovary syndrome

2021 ◽  
Author(s):  
Gürkan Çıkım ◽  
Abdullah Tok
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Vitamin D Levels

scholarly journals Associations between vitamin D levels and polycystic ovary syndrome phenotypes

2019 ◽  
Vol 44 (2) ◽  
Author(s):  
Erin M. Davis ◽  
Jennifer D. Peck ◽  
Karl R. Hansen ◽  
Barbara R. Neas ◽  
LaTasha B. Craig
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Vitamin D Levels

scholarly journals Low Vitamin D Level in Saudi Women With Polycystic Ovary Syndrome

2021 ◽  
Vol 8 ◽  
Author(s):  
Iman Abdullah Bindayel
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Serum Triglyceride ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Hydroxyvitamin D ◽  
Saudi Women ◽  
Number Of Patients ◽  
Vitamin D Levels

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. In this study, serum 25-hydroxyvitamin D levels were compared between women with and without PCOS and with regard to anthropometric indices and lipid and glucose biomarkers. Thirty-one women with PCOS and 75 controls answered a questionnaire on vitamin D, in addition to general health and lifestyle. The patients with PCOS had lower vitamin D levels (p < 0.05), a significantly higher rate of obesity (p < 0.05), and significantly higher serum triglyceride levels than did controls. The number of patients with PCOS consumed milk and dairy products (p < 0.05) and exposed to sun (p < 0.006) were lower compared to controls. Triglyceride levels were significantly correlated with body mass index (BMI); vitamin D level was not significantly correlated with anthropometrical or biochemical variables. These results affirm that vitamin D levels are lower in women with PCOS; however, despite the significantly higher proportion of obesity among patients with PCOS, hypovitaminosis was not associated with BMI. The relationship between body composition and vitamin D in PCOS and the effect of vitamin D correction on metabolic and hormonal parameters associated with PCOS must be assessed in future trials.

scholarly journals Serum Vitamin D Levels and Polycystic Ovary syndrome: A Systematic Review and Meta-Analysis

Nutrients ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 4555-4577 ◽  
Author(s):  
Chunla He ◽  
Zhoumeng Lin ◽  
Sara Robb ◽  
Amara Ezeamama
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Ovary Syndrome ◽  
Serum Vitamin D ◽  
Vitamin D Levels

scholarly journals Study of serum calcium and vitamin D levels with hormonal profile along with biochemical profile in women with polycystic ovary syndrome

2017 ◽  
Vol 6 (9) ◽  
pp. 4075
Author(s):  
Ilangovan Subashree ◽  
Umakant Ramchandra Valvekar ◽  
Geetha Prasad
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Vitamin D Deficiency ◽  
Serum Calcium ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Control Female ◽  
Hormonal Profile ◽  
Vitamin D Levels

Background: The polycystic ovary syndrome (PCOS) is one of the commonest human endocrinopathies and is increasingly recognized as a variant of the metabolic syndrome in women with the characteristic features of insulin resistance, central obesity, impaired glucose metabolism, dyslipidemia, and hypertension.Methods: This study is mainly focused on study of parameters like gonadotropin hormonal profile, serum vitamin D and calcium levels in polycystic ovary disease (PCOD). The study comprised 45 clinically proven polycystic ovary disease patients in the age range of 19-34 years. The biochemical estimations carried out in the study were – Fasting Blood sugar, LH, FSH, prolactin, 25- OH vitamin D and calcium along with anthropometric data. The values obtained were compared with age matched equal number of healthy control female subjects from the same population.Results: The serum concentration of calcium and vitamin D levels are decreased significantly (P <0.001) when compared to controls. Insulin resistance is predominantly seen in PCOS subjects. The study outlines the importance of insulin resistance, dyslipidemia, decreased serum calcium and vitamin D levels in PCOS subjects may be a cause for the progression of polycystic ovary syndrome.Conclusions: In the present study vitamin D deficiency is highly prevalent in PCOS women from this area compared to control women. We also relations of vitamin D status with insulin sensitivity, HDL-C, and C-reactive protein in PCOS patients, which support the increasing evidence that vitamin D deficiency is associated with multiple metabolic risk factors in PCOS women. A high prevalence of vitamin D deficiency and low calcium levels were observed in PCOS women from our population when compared to controls. Insulin resistance was predominantly seen in PCOS subjects when compared with controls, indicating the association of vitamin D levels with insulin resistance.

scholarly journals MON-037 Vitamin D Levels in Women with Polycystic Ovary Syndrome: Influence of Obesity

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Patricia Nieves Amelia Maidana ◽  
Gladys Isabel Fernández ◽  
Analy Fritzler ◽  
María Gabriela Ropelato ◽  
Lamas-Majek Eugenia ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Fat Distribution ◽  
Normal Weight ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Metabolic Complications ◽  
Negatively Associated ◽  
Vitamin D Levels

Abstract Introduction: Polycystic ovary syndrome (PCOS) is the most frequent cause of hyperandrogenism in women of reproductive age. Among its metabolic complications, vitamin D deficiency has been described in relation with insulin resistance’s pathophysiology and other metabolic risk factors. However, it is not clear if this deficiency is inherent to PCOS or it depends on adiposity degree. As well, it is also suggested that vitamin D could regulate leptin levels and high leptin levels should be associated with vitamin D defiency in obesity. Our aim was to evaluate the relationship between vitamin D, leptin and obesity degree in PCOS patients. Subjects and methods: In 84 PCOS women (19 -37 years) and 49 controls (22-45 years), 25 hidroxi-vitamin D (25 OH-D) was measured by direct chemoluminiscence. Body mass index (BMI) was calculated; 20% of PCOS women were overweight and 46% were obese. Waist circumference (WC) was measured as an indicator of abdominal obesity. The lipid accumulation product (LAP) index, a secondary marker of insulin resistance, was calculated (LAP: [waist (cm) - 58] x triglycerides (mmol/l)). In a subgroup of 26 patients, leptin levels were determined by ELISA method. Statistical analysis was performed through SPSS 22. Results: Variables are expressed as mean ± SD or median (range) according to distribution. The following parameters were higher in PCOS women than in controls, BMI: 29.3 (18.6-48.2) vs 22.4 (18.1-37.4) kg/m2; WC 95 ± 16 vs 82 ± 11 cm and LAP: 47.9 (1.1-198.2) vs 17.5 (6.8-93.4) cm.mmol/L, p&lt;0.0001 in all cases. 25 OH-D was lower in PCOS: 14.5 (10.0-39.0) vs 17.0 (10.0-38.8) ng/ml, p=0.024. Leptin levels in PCOS women were 10.1 ± 5.4, 26.4 ± 7.0 and 33.8 ± 16.9 ng/ml in normal weight, overweight and obese patients, respectively. After a logistic binary regression analysis, differences in 25 OH-D between groups were lost when BMI and WC were considered (p=0.556; RR=0.978; IC95% [0.909-1.063]). 25 OH-D levels were negatively associated with WC (r=-0.286, p=0.006), LAP (r=-0.333, p=0.002) and leptin (r=-0.462, p=0.017). Conclusions: although 25 OH-D levels were lower in PCOS women than in controls and negatively associated with LAP, an insulin resistant marker, the fact than differences between groups was lost after correction by BMI and WC, in addition to the correlation found between 25 OH-D and leptin levels, indicates that obesity degree and abdominal fat distribution should be responsible of decreased vitamin D levels in PCOS.

scholarly journals Assessment of Serum Vitamin D Levels in Women with Polycystic Ovary Syndrome

2018 ◽  
Vol 60 (2) ◽  
pp. 93-97
Author(s):  
Rana A. Hamdi ◽  
Zina H. Abdul-Qahar ◽  
Ekhlas J. Kadhum ◽  
Fatin A. Alsaeed
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Free Testosterone ◽  
Serum Glucose ◽  
Fasting Serum ◽  
Ovary Syndrome ◽  
Fasting Serum Glucose ◽  
Vitamin D Levels ◽  
25 Hydroxy Vitamin D

Background: Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women ofreproductive age with primary features of infertility, menstrual irregularity, and clinical or biochemicalevidence of hyperandrogenism (hirsutism, acne and high androgen level). Vitamin D has a role in thedevelopment of metabolic and endocrine abnormalities in PCOS mediated by insulin resistance.Objective: Measure serum 25-hydroxy vitamin D levels in women with polycystic ovary syndrome andcompare their levels with age and body mass index matched healthy controls. Also, assess thecorrelation between insulin resistance and 25-hydroxy vitamin D among women with PCOS.Subjects and Methods: Eighty eight women were involved in this study with age range (18-34 years).Subjects were divided into two groups: Group 1- forty five women with PCOS and Group 2- forty threewomen without PCOS (as controls).Serum 25-hydroxy vitamin D, insulin, free testosterone, Luteinizing hormone (LH), Follicle stimulatinghormone (FSH) were measured by enzyme linked immunosorbent assay (ELISA), while serum calciumand fasting serum glucose were measured by spectrophotometer.Results: Significant increase in mean value of fasting serum glucose, insulin, homeostatic modelassessment of insulin resistance (HOMA-IR), LH, LH/FSH ratio, and free testosterone with significantdecrease in mean value of serum FSH, 25-hydroxy vitamin D, and calcium for patients with PCOScomparing to age and body mass index match controls. Additionally, significant negative correlationswere found between serum 25-hydroxy vitamin D levels with fasting serum glucose (r= -0.484, p=0.01),fasting serum insulin (r= -0.422, p=0.04), and HOMA-IR (r= -0.542, p=0.0001) in women with PCOS.Conclusion: Vitamin D has a role in metabolic and hormonal disturbance seen in PCOS through impactof vitamin D on insulin releasing and function.

scholarly journals The relationship between Polycystic ovary syndrome and vitamin D levels

2015 ◽  
Vol 12 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Setenay Arzu Yılmaz ◽  
Sündüz Özlem Altınkaya ◽  
Ayşegül Kebabçılar ◽  
Özlem Seçilmiş Kerimoğlu ◽  
Aybike Tazegül Pekin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Vitamin D Levels ◽  
The Relationship
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