Influence of short-term supplementation of various quantities of organically bound selenium upon serum and urine selenium concentration

2003 ◽  
Vol 20 (04) ◽  
pp. 94-98 ◽  
Author(s):  
J. Kvicala ◽  
V. Zamrazil ◽  
J. Nemecek ◽  
V. Jiranek
2019 ◽  
Vol 19 (S1) ◽  
pp. 68-76
Author(s):  
A Nikulina

Aim. The article deals with studying the effect of a complex selenium-containing compound and physio disease-preventing means on the enhancement of biochemical indicators in freshmen living in a selenium-deficient area. Materials and methods. We conducted 12 longitudinal studies with the students of the first and second year studying at Chuvash Universities (n = 180). Selenium concentration in blood serum was established with the help of fluorometry performed according to Golubkina’s interpretation (Fluorat-02-2M). The activity of lipid peroxidation (c.u.) and antioxidant system (c.u.) was studied using induced chemiluminescence (Biochemiluminometer БХЛ-06). Results. The use of Selenes+ together with a disease-preventing photochrome session is accompanied by antioxidant, metabolic, and hemopoietic effects manifested in the increase of antioxidant activity and selenium concentration by 31.1 and 62.5 %, respectively, and the decrease of lipid peroxidation by 4.1–19.7 % compared to control values. The use of Selenes+ together with exercises contributes to less pronounced stress in the cardiovascular system both during the study and exam periods. Conclusion. Therefore, selenium correction of body adaptation with respect to a biogeochemical specifics of a region normalizes the balance between prooxidant and antioxidant elements of the antioxidant protection system and provides an accelerated shift from short-term to long-term adaptation.


1994 ◽  
Vol 45 (4) ◽  
pp. 863 ◽  
Author(s):  
BR Whelan ◽  
DW Peter ◽  
NJ Barrow

Two forms of prilled selenium fertilizer from Mintech N.Z., Na2 SeO4 (Selcote�) and BaSe04 incorporating a slow-release technology, were applied to pasture once at 10 and 20 g Se ha-1 in 1987 at Bakers Hill, Western Australia. The pasture was grazed at 10 sheep ha-1 for 3 years. In the first year, half the sheep were also treated with a selenium intra-ruminal pellet. The Selcote fertilizer produced a rapid rise in pasture selenium concentration, resulting in a similar response in the concentrations of selenium in the whole blood and plasma which reached their maximum values within 7 weeks of commencing grazing. The selenium concentration then declined until, after 15 months, there was insufficient selenium in the pastures to increase the selenium status of sheep. In contrast, the slow-release formulation provided adequate selenium in each of the 3 years with sheep reaching their maximum plasma selenium of 80 8g Se L-1 in the second and third year. At relatively low values for whole blood selenium (< 75 pg Se L-1), supplying an additional selenium source had an additive effect on selenium concentration in the blood, but at higher concentrations (> 350 8g Se L-1) additional sources of selenium only marginally increased the whole blood concentration of selenium. Plasma was a more sensitive indicator of the selenium content of pasture in the short term than whole blood. The results indicate that either Selcote or the BaSe04 fertilizer provides an effective alternative to current strategies for supplying Se to grazing animals.


2020 ◽  
Vol 134 ◽  
pp. 105218 ◽  
Author(s):  
Felix P. Phiri ◽  
E. Louise Ander ◽  
R. Murray Lark ◽  
Elizabeth H. Bailey ◽  
Benson Chilima ◽  
...  

Author(s):  
Brittany M Wilson ◽  
Ryan D Ross ◽  
Joshua J Jacobs ◽  
Dale Rick Sumner

Abstract Background Matched serum and urine samples from patients who had total hip replacement were used to assess serum-validated immunoassay reagents for use in urine. Methods Samples were evaluated by an automated electrochemiluminescent immunoassay (cobas e411; Roche Diagnostics) for C-terminal telopeptide of type I collagen isoform β (β-Crosslaps), osteocalcin N-terminal midfragment (N-MID OC), N-terminal propeptide of type I collagen (PINP), and interleukin 6 (IL-6). Spike and recovery experiments were utilized to assess urinary matrix effects. Correlations between serum and both raw and creatinine-corrected urinary measures were assessed. Short-term precision was assessed. Results Spike and recovery experiments indicated minimal matrix effects of urine for the β-Crosslaps assay. Potential matrix effects were observed for the other analytes because N-MID OC and IL-6 tended to be slightly overrecovered, whereas PINP was underrecovered. There were strong correlations between serum β-Crosslaps and raw (Spearman ρ [rs] = 0.725, P &lt; 0.0001) and creatinine-corrected (rs = 0.793, P &lt; 0.0001) urinary measures and moderate correlations between serum N-MID OC and raw (rs = 0.582, P &lt; 0.0001) and creatinine-corrected (rs = 0.482, P &lt; 0.0001) urinary measures. PINP was not detected in urine, and no significant serum–urine correlations were found for IL-6. Short-term precision for urinary levels of β-Crosslaps, N-MID OC, and IL-6 were 1.6%, 6.3% and 14.4%, respectively. Conclusions Urinary measurements of β-Crosslaps and N-MID OC assays were correlated with serum measurements and had good short-term precision. Urinary PINP was not detectable. IL-6 can be measured in urine using this technology, but the levels did not correlate with serum levels, and the short-term precision was variable.


2007 ◽  
Vol 121 (2) ◽  
pp. 180-191 ◽  
Author(s):  
Alena Pechova ◽  
Lubica Misurova ◽  
Leos Pavlata ◽  
Rudolf Dvorak

1999 ◽  
Vol 43 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Miguel Navarro-Alarcón ◽  
Herminia López-Garcia de la Serrana ◽  
Vidal Pérez-Valero ◽  
Carmen López-Martínez

1978 ◽  
Vol 24 (6) ◽  
pp. 650-653 ◽  
Author(s):  
R. Lindsay ◽  
L. E. Ramsay ◽  
J. Hettiarrachchi ◽  
D. L. Davies ◽  
G. H. Beastall

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