Crooke cell adenoma: Uncommon and aggressive variant of corticotroph adenoma

2021 ◽  
Author(s):  
Ridhi Sood ◽  
Liza Das ◽  
Kirti Gupta ◽  
Ashwani Kumar ◽  
Manjul Tripathi ◽  
...  
Keyword(s):  
Cell Adenoma ◽  
Corticotroph Adenoma ◽  
Aggressive Variant

scholarly journals Silent Crooke’s cell corticotroph adenoma of the pituitary gland presenting as delayed puberty

2017 ◽  
Vol 2017 ◽  
Author(s):  
Dinesh Giri ◽  
Federico Roncaroli ◽  
Ajay Sinha ◽  
Mohammed Didi ◽  
Senthil Senniappan
Keyword(s):  
Delayed Puberty ◽  
Clinical Impression ◽  
Childhood And Adolescence ◽  
List Type ◽  
Cell Adenoma ◽  
Optic Chiasma ◽  
Corticotroph Adenoma ◽  
Constitutional Delay ◽  
Pituitary Lesion ◽  
Corticotroph Adenomas

Summary Corticotroph adenomas are extremely rare in children and adolescents. We present a 15-year-old boy who was investigated for delayed puberty (A1P2G1, bilateral testicular volumes of 3 mL each). There was no clinical or laboratory evidence suggestive of chronic illness, and the initial clinical impression was constitutional delay in puberty. Subsequently, MRI scan of the brain revealed the presence of a mixed cystic and solid pituitary lesion slightly displacing the optic chiasma. The lesion was removed by transphenoidal surgery and the biopsy confirmed the lesion to be pituitary adenoma. Furthermore, the adenoma cells also had Crooke’s hyaline changes and were intensely positive for ACTH. However there was no clinical/biochemical evidence of ACTH excess. There was a spontaneous pubertal progression twelve months after the surgery (A2P4G4, with bilateral testicular volume of 8 mL). Crooke’s cell adenoma is an extremely rare and aggressive variant of corticotroph adenoma that can uncommonly present as a silent corticotroph adenoma in adults. We report for the first time Crooke’s cell adenoma in an adolescent boy presenting with delayed puberty. Learning points: Constitutional delay of growth and puberty (CDGP) is a diagnosis of exclusion; hence a systematic and careful review should be undertaken while assessing boys with delayed puberty. Crooke’s cell adenomas are a group of corticotroph adenomas that can rarely present in childhood and adolescence with delayed puberty. Crooke’s cell adenomas can be clinically silent but are potentially aggressive tumours that require careful monitoring.

Ultrastructural Classification of Pituary Adenomas

1990 ◽  
Vol 48 (3) ◽  
pp. 258-258
Author(s):  
S. Arumugam ◽  
Sarasa Bharati Arumugam
Keyword(s):  
Cytoplasmic Organelle ◽  
Null Cell ◽  
Cell Adenoma ◽  
Mixed Cell ◽  
Light Microscope Level ◽  
Null Cell Adenoma ◽  
Growth Hormone Cell ◽  
Ultrastructural Characteristics ◽  
Organelle Morphology

Adenoaas of the pituitary are no longer classified based on their tinctorial affinity to dyes. With the advent of the newer methods of sophisticated technology, it is now possible to classify. These depending upon the type of hormone secreted based either on histochemical techniques or on ultrastructural characteristics. The latter provides an insight into the cytoplasmic organelle morphology which offers a delightful feast to the eye as well.This paper presents the ultrastructural characters of the pituitary adenoma as seen in Madras. 171 adenomas (124 males and 47 females) were seen during 1972-1989, classified at the light microscope level as 159 chromophobe, 2 basophilic, 4 eosinophilic and 6 mixed adenomas.Ultrastructural examination showed that the sparsely granular prolactin cell adenoma is the commonest adenoma to be encountered closely followed by the growth hormone cell adenoma, null cell adenoma, the mixed cell adenoma and others.

Recurrent Liver Cell Adenoma

1959 ◽  
Vol 37 (6) ◽  
pp. 760-765 ◽  
Author(s):  
S.W. Berkheiser
Keyword(s):  
Liver Cell ◽  
Cell Adenoma ◽  
Liver Cell Adenoma

Pigmented Liver Cell Adenoma with Nodule-in-Nodule Appearance: Case Report

2004 ◽  
Vol 51 (3) ◽  
pp. 317
Author(s):  
Hyun Jun Choi ◽  
Jun Hyun Yun ◽  
Ji Hyeo Choi ◽  
Ju Hyun Im ◽  
Se Jong Kim ◽  
...  
Keyword(s):  
Case Report ◽  
Liver Cell ◽  
Cell Adenoma ◽  
Liver Cell Adenoma

Silent corticotroph adenoma: Experience with six cases

2020 ◽  
Author(s):  
Soler Guillermo Serra ◽  
Barceló Carlos Antich ◽  
Cubas Javier Bodoque ◽  
Fernández Honorato García ◽  
Bonet Antonio Mas ◽  
...  
Keyword(s):  
Corticotroph Adenoma ◽  
Silent Corticotroph Adenoma

Sebaceous cell adenoma. rare intra-oral occurrence of a tumour which is a frequent marker of torre’s syndrome

Pathology ◽  
1987 ◽  
Vol 19 (2) ◽  
pp. 204-208 ◽  
Author(s):  
John W. Ferguson ◽  
Colin P. Geary ◽  
Alton D. MacAlister
Keyword(s):  
Cell Adenoma

scholarly journals Management of Basal Cell Adenoma of Accessory Parotid Gland Through Transoral Approach: Report of a Rare Case With Review

2021 ◽  
Vol 6 ◽  
pp. 247275122110308
Author(s):  
Charudatta Naik ◽  
Sanjay Joshi ◽  
Bhupendra Mhatre ◽  
Sneha Punamiya
Keyword(s):  
Parotid Gland ◽  
Basal Cell ◽  
Benign Tumor ◽  
Transoral Approach ◽  
Surgical Approaches ◽  
Basal Cell Adenoma ◽  
Diagnostic Dilemma ◽  
Cell Adenoma ◽  
Rare Benign Tumor ◽  
Accessory Parotid Gland

Diagnosis of mid-cheek mass has always been a diagnostic dilemma for clinicians. The incidence of the accessory parotid gland (APG) has been well documented in the literature. However, a diverse spectrum of pathologies can arise from this accessory parotid tissue. Basal cell adenoma is a rare benign tumor that predominantly affects the parotid gland. Its occurrence in the accessory parotid gland has been documented in 9 cases till date. Surgical approaches for the management of such APG lesions have been in debate. This report documents a case of Basal Cell Adenoma arising in accessory parotid tissue in a 55-year-old woman who was treated by transoral excision. This paper also reviews previously documented cases of all APG lesions and attempts to elucidate the rationale for selecting an appropriate surgical approach.

Sign in / Sign up

Export Citation Format

Share Document