Prolactin-cell adenoma with signet-ring cells: a case report

2011 ◽  
Vol 30 (07) ◽  
pp. 192-196 ◽  
Author(s):  
E. Binello ◽  
C. Cunliffe ◽  
K.D. Post ◽  
G.M. Kleinman
Keyword(s):  
Case Report ◽  
Cell Adenoma ◽  
Signet Ring Cells ◽  
Prolactin Cell ◽  
Signet Ring

Cytology Detects Endobronchial Metastasis from Appendiceal Signet-Ring Cell Carcinoma in the Absence of Radiographic Lung Masses: A Case Report

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S44-S44
Author(s):  
B W Taylor ◽  
K Hummel ◽  
Y Xu
Keyword(s):  
Case Report ◽  
Respiratory Distress ◽  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Endobronchial Metastasis ◽  
Signet Ring ◽  
Ring Cell ◽  
The Right

Abstract Introduction/Objective Endobronchial metastasis (EBM) is uncommon, with a reported prevalence of 2% in cases of non-lung primary malignancies. The most frequently observed carcinomas in EBM are from breast, colon, and renal origins. We present a rare case of endobronchial metastasis from a primary tumor of the appendix without lung masses by computed tomography (CT). Methods/Case Report An 83-year-old woman with signet-ring cell carcinoma of the appendix underwent right hemicolectomy and chemotherapy. Two years later, she returned with intractable nausea and vomiting, and respiratory distress. CT of the chest demonstrated diffuse bilateral pulmonary opacities without lung masses. CT of the abdomen showed peritoneal carcinomatosis. Cytology of ascitic fluid displayed metastasis of the patient’s known appendiceal tumor. Bronchoscopy found significant friable debris appearing to be tumor tissue and occluding multiple bronchioles in the right lung. A bronchoalveolar lavage (BAL) specimen from the right lung was sent for liquid-based cytology, which revealed a few atypical cells with eccentric nuclei and intracytoplasmic vacuoles, abundant macrophages, degenerated mixed inflammatory cells, and scattered bronchial epithelial cells. Cell block demonstrated signet-ring cells mimicking macrophages and infiltrating into small fragments of bronchiolar wall. The signet-ring cells were morphologically similar to those found in the ascitic fluid and the patient’s primary tumor, and were highlighted by mucicarmine stain and immunohistochemical stains for CDX-2 and CK20, but not CK7. Results (if a Case Study enter NA) N/A Conclusion Collectively, the findings supported the diagnosis of endobronchial metastasis of signet-ring cell carcinoma from the lower gastrointestinal tract, i.e. the patient’s known appendiceal primary. Our case demonstrates a rare endobronchial metastasis of a primary neoplasm of the appendix, an important diagnostic consideration when evaluating respiratory distress in patients with such cancer histories. We have described the significant role of BAL cytology to uncover endobronchial metastases without lung masses by CT, and illustrated the finding of signet-ring cells mimicking macrophages in a BAL cytology specimen.

scholarly journals Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report

2007 ◽  
Vol 125 (5) ◽  
pp. 297-299 ◽  
Author(s):  
Marcelo Lorenzi Marques ◽  
Gabriel Salum D'Alessandro ◽  
Daher Cezar Chade ◽  
Valéria Pereira Lanzoni ◽  
Samuel Saiovici ◽  
...  
Keyword(s):  
Case Report ◽  
Mucinous Adenocarcinoma ◽  
Rare Case ◽  
Bladder Tumor ◽  
Colorectal Adenocarcinoma ◽  
Signet Ring Cell ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Ring Cell ◽  
Primary Bladder

CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological patterns are even rarer and it is often difficult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of digestive tract tumor and for confirmation that it was a primary bladder tumor, an immunohistochemistry study was performed.

scholarly journals Polyserositis revealing a signet ring cells gastric adenocarcinoma in a 27 years old male patient: A case report.

2021 ◽  
Author(s):  
Zahid Talibi Alaoui ◽  
Salah Eddine Youbi ◽  
Fatima Ihbibane ◽  
Hind Rachidi ◽  
Fatima Ezzahra Hazmiri ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Emergency Department ◽  
Case Report ◽  
Clinical Improvement ◽  
Gastric Adenocarcinoma ◽  
Male Patient ◽  
Signet Ring Cells ◽  
Signet Ring

Abstract Gastric cancer remains one of the most common and deadly cancers worldwide, especially among old males. It is rare in the younger population (< 30 years old). We describe the case of a 27 years old male patient, presenting to the emergency department, with exsudative polyserositis, initially misdiagnosed and treated as a multifocal tuberculosis with no clinical improvement, later revealing a metastatic signet ring cells gastric adenocarcinoma.

Prostate mucinous adenocarcinoma with signet ring cells: a case report and literature review

2006 ◽  
Vol 3 (5) ◽  
pp. 379-380
Author(s):  
Yi Wang ◽  
Guang Sun ◽  
Jiangang Pan ◽  
Jiwu Chang ◽  
Shumin Zhang ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Mucinous Adenocarcinoma ◽  
Signet Ring Cells ◽  
Signet Ring
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