Hemophagocytic lymphohistiocytosis in a pancreas-kidney transplant recipient: response to dexamethasone and cyclosporine

2008 ◽  
Vol 70 (07) ◽  
pp. 82-86 ◽  
Author(s):  
J.M. González-Posada ◽  
D. Hernández ◽  
A. Martin ◽  
J.M. Raya ◽  
S. Pitti ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Kidney Transplant Recipient

scholarly journals Secondary Hemophagocytic Lymphohistiocytosis Complicated by a Cavitary Lung Lesion in a Kidney Transplant Recipient

2021 ◽  
pp. 195-203
Author(s):  
Katarzyna Muras-Szwedziak ◽  
Maciej Tylski ◽  
Anna Masajtis-Zagajewska ◽  
Michał Nowicki
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Laboratory Tests ◽  
Kidney Transplant Recipient ◽  
Bone Marrow Aspiration ◽  
Rare Condition ◽  
High Dose ◽  
Kidney Transplant Patient ◽  
Kidney Transplant Recipients

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon life-threatening condition caused by an uncontrolled immunological response. It can develop secondary to malignancies, infections, systemic diseases, and immunosuppression. Multiple risk factors may present in kidney transplant recipients; however, the cases of HLH in this population have been described sparsely. We report a case of a 39-year-old female kidney transplant recipient who presented to the hospital nearly 3.5 years after the transplantation with general malaise, recent history of weight loss, fevers, and persistent anemia. Laboratory tests showed pancytopenia, hyperferritinemia, hypertriglyceridemia, and increased activity of lactate dehydrogenase. A bone marrow aspiration revealed hemophagocytosis, which led to the diagnosis of HLH. Therapy consisting of high-dose steroids and plasma exchanges was administered, resulting in a significant improvement of blood count parameters and the patient’s general condition. While searching for the triggering disease, a single cavitary lesion in the right lung was revealed in a chest radiograph. Computed tomography scan, bronchoscopy, and additional laboratory testing did not reveal a definitive cause of the lesion. We suspect that the lesion may be a consequence of HLH. The patient was disqualified from thoracic surgery due to multiple comorbidities. Even though HLH is a rare condition, it should be taken into consideration in a kidney transplant patient presenting with unspecific symptoms accompanied by a bicytopenia. It has an unpredictable course that often results in serious complications. Thus close follow-up of the patient and a wide array of imaging and laboratory tests remain crucial.

Ehrlichia ‐induced hemophagocytic lymphohistiocytosis in a pediatric kidney transplant recipient

2021 ◽  
Author(s):  
Nisha S. Singh ◽  
Alexa L. Pagano ◽  
Allyson J. Hays ◽  
Alexander Kats ◽  
Steven M. Dahl ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Kidney Transplant Recipient

scholarly journals Hemophagocytic lymphohistiocytosis in an adult kidney transplant recipient successfully treated by plasmapheresis

Medicine ◽  
2017 ◽  
Vol 96 (50) ◽  
pp. e9283 ◽  
Author(s):  
Christian Nusshag ◽  
Christian Morath ◽  
Martin Zeier ◽  
Markus A. Weigand ◽  
Uta Merle ◽  
...  
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Kidney Transplant Recipient ◽  
Adult Kidney ◽  
Adult Kidney Transplant Recipient

scholarly journals Multiple papules on the face in a kidney transplant recipient

2020 ◽  
Vol 21 (1) ◽  
pp. 428-430
Author(s):  
Jin Sasaki ◽  
Satoru Shinkuma ◽  
Riichiro Abe
Keyword(s):  
Transplant Recipient ◽  
Kidney Transplant ◽  
Kidney Transplant Recipient ◽  
The Face
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