A case of monoclonal immunoglobulin light- and heavy-chain deposition disease exhibiting atypical deposition with fibrillary structures, successfully treated with chemotherapy

2005 ◽  
Vol 64 (09) ◽  
pp. 221-227 ◽  
Author(s):  
A. Nakatsuka ◽  
Y. Maeshima ◽  
A. Sarai ◽  
H. Yanai ◽  
H. Sugiyama ◽  
...  
Keyword(s):  
Heavy Chain ◽  
Monoclonal Immunoglobulin ◽  
Deposition Disease ◽  
Heavy Chain Deposition Disease

scholarly journals Comprehensive molecular characterization of a heavy chain deposition disease case

Haematologica ◽  
2018 ◽  
Vol 103 (11) ◽  
pp. e557-e560 ◽  
Author(s):  
Sébastien Bender ◽  
Maria Victoria Ayala ◽  
Vincent Javaugue ◽  
Amélie Bonaud ◽  
Michel Cogné ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Heavy Chain ◽  
Deposition Disease ◽  
Disease Case ◽  
Heavy Chain Deposition Disease

Other consequences from monoclonal immunoglobulins/fragments

2018 ◽  
Author(s):  
Fernando C. Fervenza ◽  
An S. De Vincent Rajkumar ◽  
An S. De Vriese ◽  
Sanjeev Sethi
Keyword(s):  
Heavy Chain ◽  
Renal Damage ◽  
Great Majority ◽  
Monoclonal Immunoglobulin ◽  
Physiochemical Properties ◽  
Renal Lesions ◽  
Heavy Chains ◽  
Cast Nephropathy ◽  
Monoclonal Immunoglobulins ◽  
Heavy Chain Deposition Disease

Renal damage secondary to deposition of monoclonal immunoglobulin can occur due to accumulation of either light chains, heavy chains, or both. These include myeloma kidney (cast nephropathy), light-chain and heavy-chain amyloidosis, and light- and heavy-chain deposition disease. Renal damage secondary to deposition of both chains is far less common. In the great majority of these cases the M-component is immunoglobulin G, but the spectrum of renal lesions associated with monoclonal gammopathy is extensive and depends on the physiochemical properties of the immunoglobulin produced.This chapter discusses two important, but less recognized disorders associated with monoclonal immunoglobulins: membranoproliferative glomerulonephritis and acquired Fanconi syndrome.

scholarly journals Monoclonal gammopathy of renal significance with heavy‐chain deposition disease in renal allograft: challenges in the diagnosis and management

2019 ◽  
Vol 32 (7) ◽  
pp. 769-770
Author(s):  
Lavleen Singh ◽  
Arun Kumar Subbiah ◽  
Geetika Singh ◽  
Soumita Bagchi ◽  
Amit Kumar Dinda ◽  
...  
Keyword(s):  
Heavy Chain ◽  
Monoclonal Gammopathy ◽  
Renal Allograft ◽  
Diagnosis And Management ◽  
Deposition Disease ◽  
Heavy Chain Deposition Disease

scholarly journals AJKD Atlas of Renal Pathology: Heavy Chain Deposition Disease

2016 ◽  
Vol 67 (3) ◽  
pp. e11-e12 ◽  
Author(s):  
Agnes B. Fogo ◽  
Mark A. Lusco ◽  
Behzad Najafian ◽  
Charles E. Alpers
Keyword(s):  
Heavy Chain ◽  
Renal Pathology ◽  
Deposition Disease ◽  
Heavy Chain Deposition Disease

scholarly journals Gamma 1-heavy chain deposition disease accompanied by IgG kappa in serum, urine, and bone marrow

2013 ◽  
Vol 3 (1) ◽  
pp. 44-48 ◽  
Author(s):  
Keiichi Kaneko ◽  
Koichi Seta ◽  
Jun Soma ◽  
Takashi Kuwahara ◽  
Mitsuteru Koizumi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Heavy Chain ◽  
Deposition Disease ◽  
Heavy Chain Deposition Disease

scholarly journals Recurrent light and heavy chain deposition disease after renal transplantation

2005 ◽  
Vol 20 (7) ◽  
pp. 1487-1491 ◽  
Author(s):  
Bassam Alchi ◽  
Shinichi Nishi ◽  
Seitaro Iguchi ◽  
Masaaki Shimotori ◽  
Minoru Sakatsume ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Heavy Chain ◽  
Deposition Disease ◽  
Heavy Chain Deposition Disease
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