Safety of vancomycin in patients with moderate and severe renal dysfunction

2021 ◽  
Author(s):  
Mariko Awaya ◽  
Hironori Tanaka ◽  
Ayako Suzuki ◽  
Risa Yamauchi ◽  
Yumiko Kusunoki ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Severe Renal Dysfunction

scholarly journals Predictors and Evolution of Renal Function during 9 Years Following Heart Transplantation

2000 ◽  
Vol 11 (5) ◽  
pp. 951-957
Author(s):  
BJÖRN LINDELÖW ◽  
CLAES-HÅKAN BERGH ◽  
HANS HERLITZ ◽  
FINN WAAGSTEIN
Keyword(s):  
Renal Function ◽  
Heart Transplantation ◽  
Cyclosporin A ◽  
Renal Dysfunction ◽  
University Hospital ◽  
Channel Blockers ◽  
Converting Enzyme Inhibitors ◽  
Preoperative Serum ◽  
Recipient Age ◽  
Severe Renal Dysfunction

Abstract. Over a 9-yr period, heart transplantation was performed in 200 patients at Sahlgrenska University Hospital. Of these 200 patients, 151 were followed for 1 to 9 yr with regard to renal function, hemodynamics, cyclosporin A concentrations, and complications. Patients with a preoperative serum creatinine >130 μmol/L received inotropic drugs to test for reversibility of renal dysfunction. The end point was graft failure. The average preoperative GFR of 66 ± 17 ml/min per 1.73 m2 declined to 52 ± 19, 44 ± 16, and 37 ± 17 at 1, 5, and 9 yr after heart transplantation, respectively. Altogether, the average GFR declined by 44%. There was no significant correlation between the preoperative GFR and postoperative renal function or survival. Recipient age was a predictor of renal function during the entire follow-up. Severe renal dysfunction (GFR <20 ml/min per 1.73 m2) developed in 20% of the patients, which was predicted by the recipient age at transplantation together with the GFR 1 yr after transplantation. A nomogram that shows the risk of developing severe renal dysfunction after heart transplantation is presented. Cyclosporin A concentrations and treatment with statins, calcium channel blockers, or angiotensin-converting enzyme inhibitors did not correlate with the evolution of renal function. Patients with a preoperative depressed renal function who improved on inotropic treatment seemed to have a poorer outcome compared with the other study patients.

scholarly journals Sofosbuvir-based regimens for the treatment of chronic hepatitis C in severe renal dysfunction

2017 ◽  
Vol 1 (3) ◽  
pp. 248-255 ◽  
Author(s):  
Paula Cox-North ◽  
Kelsey L. Hawkins ◽  
Sean T. Rossiter ◽  
Marie N. Hawley ◽  
Renuka Bhattacharya ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Renal Dysfunction ◽  
Chronic Hepatitis C ◽  
Severe Renal Dysfunction

scholarly journals 260. LONG TERM OUTCOMES OF PATIENTS WITH ANCA-ASSOCIATED VASCULITIS PRESENTING WITH SEVERE RENAL DYSFUNCTION

Rheumatology ◽  
2019 ◽  
Vol 58 (Supplement_2) ◽  
Author(s):  
Stephen Mcadoo ◽  
Anisha Tanna ◽  
Amy Kang ◽  
Sultana Azam ◽  
Kavita Gulati ◽  
...  
Keyword(s):  
Renal Dysfunction ◽  
Long Term Outcomes ◽  
Anca Associated Vasculitis ◽  
Severe Renal Dysfunction

scholarly journals TCT-240 Severe Renal Dysfunction In Patients Admitted With Cardiogenic Shock Complicating AMI - Early And 2-Year Outcomes From The PL-ACS Registry

2013 ◽  
Vol 62 (18) ◽  
pp. B79
Author(s):  
Michal Hawranek ◽  
Marek Gierlotka ◽  
Mariusz Gasior ◽  
Mateusz Tajstra ◽  
Krzysztof Wilczek ◽  
...  
Keyword(s):  
Cardiogenic Shock ◽  
Renal Dysfunction ◽  
Severe Renal Dysfunction

scholarly journals Rare complication of milk-alkali ingestion: severe pancreatitis and acute kidney injury in a chronic hypocalcaemic patient with DiGeorge’s syndrome

2019 ◽  
Vol 12 (3) ◽  
pp. e226761 ◽  
Author(s):  
Rajarshi Bhadra ◽  
Fareeha Ahmed Khan ◽  
Mona Soliman ◽  
Meyappan Somasundaram ◽  
Daniel V Iltchev ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Renal Dysfunction ◽  
Epigastric Pain ◽  
Calcium Supplementation ◽  
Rare Complication ◽  
Biliary Duct ◽  
Thiazide Diuretics ◽  
Prolonged Stay ◽  
Calcium Supplements ◽  
Severe Renal Dysfunction

Injudicious use of over-the-counter calcium supplements has resulted in increased incidences of hypercalcaemia and related complications. We present a case of acute pancreatitis in a chronic hypocalcaemic patient of DiGeorge’s syndrome. The patient came into the ED with sepsis syndrome, right upper quadrant and epigastric pain and no obvious source of infection. Lab results and imaging were indicative of acute pancreatitis. There was severe renal dysfunction. The patient needed haemodialysis and had a prolonged stay in intensive care. The medical history was negative for biliary duct pathology or alcohol use. The patient had vomiting and diarrhoea in the nursing home for about a week, but she continued to receive her regular medications that included the calcium supplements and thiazide diuretics. It is likely that a complex interplay between calcium supplementation, dehydration and thiazide diuretics resulted in the development of acute pancreatitis and severe renal dysfunction in a chronic hypocalcaemic patient.

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