A case of membranous nephropathy with Kimura’s disease

2021 ◽  
Author(s):  
Feng Yi ◽  
Jun Jiang ◽  
Jiamei Li ◽  
Lei Lan
Keyword(s):  
Membranous Nephropathy ◽  
Kimura’S Disease

scholarly journals Rituximab Treatment in a Patient with Kimura Disease and Membranous Nephropathy: Case Report

2021 ◽  
pp. 116-123
Author(s):  
Roald Vissing-Uhre ◽  
Alastair Hansen ◽  
Susanne Frevert ◽  
Ditte Hansen
Keyword(s):  
Case Report ◽  
Membranous Nephropathy ◽  
Neck Region ◽  
Renal Diseases ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Kimura Disease ◽  
Chronic Inflammatory Disorder ◽  
Eosinophil Granulocytes ◽  
Anti Cd20

Kimura disease (KD) is a chronic, inflammatory disorder with slowly developing subcutaneous tumor-like swellings, often occurring in the head and neck region. KD is diagnosed based on histology, elevated levels of immunoglobulin type E, and increased peripheral eosinophil granulocytes. KD may coexist with glomerular renal diseases, and this case report is based on a patient with KD-associated membranous nephropathy. Patients with membranous nephropathy without KD have demonstrated responsiveness to treatment with monoclonal anti-CD20 antibodies. This case report is the first to investigate the effect of rituximab treatment in a patient with KD-associated membranous nephropathy. A 30-year-old Italian man living in Denmark was diagnosed with Kimura’s disease based on subcutaneous nodules with eosinophil angiolymphoid hyperplasia. The patient was admitted to the hospital due to nephrotic syndrome. Serology showed eosinophil granulocytosis and negative PLA2-receptor antibody. Renal biopsy showed membranous nephropathy, and the patient was treated with systemic methylprednisolone followed by cyclosporin and then cyclophosphamide with only partial remission. Ultimately, treatment with intravenous rituximab was initiated, which resulted in overall remission and no nephrotic relapses at 30 months of follow-up. Thus, intravenous rituximab effectively decreased proteinuria and prevented nephrotic relapses in a patient with treatment-refractory membranous nephropathy due to KD.

Kimura’s Disease and Membranous Nephropathy

Nephron ◽  
1991 ◽  
Vol 58 (4) ◽  
pp. 472-474 ◽  
Author(s):  
AB. Akosa ◽  
A. Sherif ◽  
C.G.H. Maidment
Keyword(s):  
Membranous Nephropathy ◽  
Kimura’S Disease

scholarly journals Membranous Nephropathy and Kimura's Disease Manifesting a Hip Mass. A Case Report with Literature Review

2010 ◽  
Vol 49 (14) ◽  
pp. 1405-1409 ◽  
Author(s):  
Yoko Obata ◽  
Akira Furusu ◽  
Tomoya Nishino ◽  
Hiroshi Ichinose ◽  
Aki Ohnita ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Membranous Nephropathy ◽  
Kimura’S Disease

A Case of Pseudolymphoma Mimicking Kimura's Disease

2004 ◽  
Vol 66 (4) ◽  
pp. 364-370
Author(s):  
Yumiko KUBOTA ◽  
Juichiro NAKAYAMA ◽  
Hiromaro KIRYU ◽  
Hiroshi IWASAKI
Keyword(s):  
Kimura’S Disease
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