Mean platelet volume/platelet count ratio and mortality in patients on peritoneal dialysis

2018 ◽  
Vol 90 (3) ◽  
pp. 205-211
Author(s):  
Yan Zhu ◽  
Fenfen Peng ◽  
Yihua Chen ◽  
Wenjing Chen ◽  
Weidong Zhou ◽  
...  
Keyword(s):  
Platelet Count ◽  
Peritoneal Dialysis ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio

MO714MEAN PLATELET VOLUME / PLATELET COUNT RATIO IN PERITONEAL DIALYSIS: ASSOCIATION TO PERITONEAL TRANSPORT STATUS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Matthias Zeiler ◽  
Antonio Federico ◽  
Tania Monteburini ◽  
Stefano Santarelli
Keyword(s):  
Platelet Count ◽  
Peritoneal Dialysis ◽  
Mean Platelet Volume ◽  
Endothelial Activation ◽  
Wilcoxon Test ◽  
Platelet Volume ◽  
Reactive Protein ◽  
Count Ratio ◽  
Peritoneal Transport ◽  
Peritoneal Function

Abstract Background and Aims Mean platelet volume volume (MPV) is gaining scientific interest with regard to cardiovascular risk stratification. The MPV/platelet count ratio seems to be more specific than mean platelet volume alone as a surrogate parameter for platelet activation. The MPV/platelet ratio might be of interest in peritoneal dialysis (PD) as the distribution and integrity of endothelial – platelet interaction in the abdominal space determines its function. The aim of the study was to evaluate the associations between MPV/platelet ratio and peritoneal transport status. Method In 123 PD patients (median age 65 years) MPV and platelet count were measured together with anthropometric patient data and peritoneal function at catheter placement and after 6 months during the first peritoneal equilibration test (PET). MPV and platelet count were determined with a fully-automated hematological analyzer. Correlation analysis was performed. Results The MPV/platelet ratio decreased significantly from 3.99% at placement to 3.50% at the first PET (median values, Wilcoxon test p<0.001). Neither anthropometric data, nor creatinine clearance, nor BUN clearance, nor Kt/V (renal, peritoneal, total), nor erythrocyte sedimentation rate, nor C reactive protein were associated to MPV/platelet ratio. Only D/P urea and D/P creatinine were significantly correlated to MPV/platelet ratio (D/P urea r=0.223, p=0.01; D/P creatinine r=0.199, p=0.03). Slow transporters presented a significantly lower MPV/platelet ratio than average transporters (median values, 3.49% versus 3.83%, Mann-Whitney test p=0.03). Conclusion Peritoneal dialysis is reducing significantly the MPV/platelet ratio. Differences in MPV/platelet ratio are reflected in the peritoneal transport status at 6 months after dialysis start. The reduction of the MPV/platelet ratio might respect a reduced platelet and endothelial activation even in the abdominal space.

Mean platelet volume/platelet count ratio in hepatocellular carcinoma

Platelets ◽  
2012 ◽  
Vol 24 (5) ◽  
pp. 375-377 ◽  
Author(s):  
Sun Young Cho ◽  
John Jeongseok Yang ◽  
Eunkyoung You ◽  
Byung-Ho Kim ◽  
Jaejun Shim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Platelet Count ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio

Mean platelet volume and mean platelet volume/platelet count ratio commensurate to severity in ischemic stroke

2018 ◽  
Vol 6 (4) ◽  
pp. 6 ◽  
Author(s):  
Ashish Goel ◽  
Sukhmani Saini ◽  
Arsalan Moinuddin ◽  
Rajesh Misra ◽  
Manisha Gupta ◽  
...  
Keyword(s):  
Platelet Count ◽  
Ischemic Stroke ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio

Mean platelet volume/platelet count ratio in anemia

Platelets ◽  
2012 ◽  
Vol 24 (3) ◽  
pp. 244-245 ◽  
Author(s):  
Sun Young Cho ◽  
John Jeongseok Yang ◽  
Jin-Tae Suh ◽  
Woo-In Lee ◽  
Hee Joo Lee ◽  
...  
Keyword(s):  
Platelet Count ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Count Ratio
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