The impact of residual renal function on quality of life in patients with peritoneal dialysis

2018 ◽  
Vol 90 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Wei Zhou ◽  
Weifeng Hu ◽  
Guofeng Han ◽  
Huiling Wang ◽  
Jinyuan Zhang ◽  
...  
2020 ◽  
Vol 40 (4) ◽  
pp. 422-424
Author(s):  
Elsa Soares ◽  
Patricia Valério ◽  
Catarina Abrantes ◽  
Teresa Furtado ◽  
José Assunção ◽  
...  

The residual renal function (RRF) in a peritoneal dialysis (PD) patient is clinically important because it contributes to dialytic adequacy, quality of life and mortality. We present the case of a patient in PD with a marked decrease in RRF. Even after the increase of dialysis, the patient maintained asthenia and anorexia, was prostrate and showed no improvement analytically. The study revealed hypothyroidism, iatrogenic due to the use of amiodarone. After suspension of the drug and replacement with levothyroxine, there was a normalization of thyroid function and recovery of RRF to baseline values. A thyroid dysfunction is associated with several changes in renal function, in most cases reversible after obtaining euthyroid state. The association between thyroid dysfunction and loss of RRF continues to be under-recognized. We should consider monitoring thyroid function annually as routine in this group of patients.


2000 ◽  
Vol 20 (4) ◽  
pp. 412-417 ◽  
Author(s):  
Amedeo F. De Vecchi ◽  
Antonio Scalamogna ◽  
Silvia Finazzi ◽  
Patrizia Colucci ◽  
Claudio Ponticelli

Background Incremental dialysis has been suggested for patients with some residual renal function. However, very little published clinical data exist on the feasibility of this schedule. Objectives To assess feasibility of incremental dialysis, with regard to its effect, complications, and impact on quality of life. Design Pilot prospective study, not controlled. Setting Nephrology division, public clinical research hospital. Patients Twenty-five patients (19 men, mean age 61 ± 13 years, body weight 63 ± 11 kg) began peritoneal dialysis (the first treatment of uremia) with a single nightly exchange lasting 10 hours or 2 daily exchanges over 12 hours according to creatinine clearance and Kt/V. Patients gave informed consent and reported their work activity, degree of rehabilitation, and their quality of life by answering a questionnaire prepared for this purpose. Outcome Measures Survival rate, complications related to peritoneal dialysis, and residual renal and peritoneal clearances. Results During the study period no patient died. Complications related to dialysis were peritonitis (0.41 episodes/year) and exit-site infection (0.32 episodes/year). All patients continued to work with full rehabilitation and considered 1 or 2 exchanges per day less troublesome than 3 or 4. Conclusions Incremental dialysis is well accepted by patients and staff. This technique does not involve a high risk of complications and is economical. Therefore incremental dialysis is feasible.


2007 ◽  
Vol 27 (2_suppl) ◽  
pp. 158-163
Author(s):  
Philip KamTao Li ◽  
Yuk Lun Cheng

Dialysis is not the ideal renal replacement therapy because it does not fully restore all kidney functions. Increasing evidence suggests that preservation of residual renal function is associated with a survival benefit, a decrease in morbidity, better nutrition, a lower level of inflammatory markers, an improved quality of life, and cost savings by obviating the need for more peritoneal dialysis exchanges and possibly by reducing the requirement for antihypertensive agents, phosphate binders, and erythropoietin. In the present article, we review the impact of residual renal function on patient outcomes and the renoprotective strategies available in patients on peritoneal dialysis.


2020 ◽  
Vol 3 (2) ◽  
pp. 93-103
Author(s):  
Abdelaali Bahadi ◽  
Sanaa Benbria ◽  
Hicham Rafik ◽  
Driss El Kabbaj

Abstract : Introduction: Peritoneal dialysis (PD) is as effective as hemodialysis and often provides a better quality of life for patients. Despite this, the replacement therapy remains little established in our country with a prevalence of less than 1% of patients with end-stage renal disease. The objective of this work is to report the development and complications of PD in our center. Patients and methods: This is a retrospective study including all patients on PD between October 2008 and March 2019. We noted their demographic and clinical data at their initiation in peritoneal dialysis and we followed their evolution to discuss infectious and mechanical complications as well as the causes of PD exit. Results: During the study period, 456 patients were admitted for end-stage renal disease. Among these patients, only 28 (6.1%) were put on PD including two diabetics. Their average age was 37.7 years with a sex ratio of 0.8. The average body surface area was 1.59 m² with an average residual renal function of 6.05 ml / min. PD was chosen as the first intention in 20 patients while 8 patients were on hemodialysis. The evolution was marked by a median survival of the technique of 18.5 months characterized by 8 episodes of peritonitis in 4 patients corresponding to a rate of 1 episode over 56 months. Regarding mechanical complications, we noted 9 omentum aspirations, 1 leak in one case and 1 umbilical hernia requiring surgical recovery in a patient. Out of 28 patients, 17 discharges were identified; 10 patients (67%) were transferred to hemodialysis, 4 died and only 3 patients (18%) were transplanted. The final transfer to hemodialysis was related to mechanical complications in 5 cases, loss of ultrafiltration in one case, repeated hydro-sodium overload in one case, peritonitis in one case and social reasons in two cases. Conclusion: PD is an effective technique which preserves residual renal function and quality of life but its prevalence remains low in the order of 6% of patients treated for end-stage renal disease. The complications are dominated in our context by the mechanical complications main cause of final transfer in hemodialysis.


2018 ◽  
Vol 1 (1) ◽  
pp. 5-8
Author(s):  
William White ◽  
Edwina Brown

AbstractPeritoneal dialysis (PD) can provide an improved quality of life to older patients requiring renal replacement therapy (RRT) compared to in-centre haemodialysis (HD). Frailty in the elderly poses challenges to PD, which may be met by assisted PD, and integration with geriatric and palliative services. The focus of PD care in the elderly should be on meeting patients’ goals, controlling symptoms, maintaining fluid balance and maintaining residual renal function


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii617-iii617
Author(s):  
Kallel Hend ◽  
Krid Madiha ◽  
Jbeli Hela ◽  
Khedher Rania ◽  
Ben Mami Ikram ◽  
...  

2019 ◽  
Vol 39 (2) ◽  
pp. 112-118 ◽  
Author(s):  
Osasuyi Iyasere ◽  
Edwina Brown ◽  
Fabiana Gordon ◽  
Helen Collinson ◽  
Richard Fielding ◽  
...  

Background In-center hemodialysis (HD) has been the standard treatment for older dialysis patients, but reports suggest an associated decline in physical and cognitive function. Cross-sectional data suggest that assisted peritoneal dialysis (aPD), an alternative treatment, is associated with quality of life (QoL) outcomes that are comparable to in-center HD. We compared longitudinal changes in QoL between modalities. Methods We enrolled 106 aPD patients, matched with 100 HD patients from 20 renal centers in England and Northern Ireland. Patients were assessed quarterly for 2 years using the Hospital Anxiety and Depression Scale (HADS), SF-12 physical and mental scores, symptom score, Illness Intrusiveness Rating Scale (IIRS), Barthel's score, and the Renal Treatment Satisfaction Questionnaire (RTSQ). Mixed model analysis was used to assess the impact of dialysis modality on these outcomes during follow-up. P values were adjusted for multiple significance testing. Results Multivariate analysis showed no difference in any of the outcome measures between aPD and HD. Longitudinal trends in outcomes were also not significantly different. Higher age at baseline was associated with lower IIRS and RTSQ scores during follow-up. One-hundred and twenty-five (60.6%) patients dropped out of the study: 59 (28.6%) died, 61 (29.6%) withdrew during follow-up, and 5 (2.5%) were transplanted. Conclusions Quality of life outcomes in frail older aPD patients were equivalent to those receiving in-center HD. Assisted PD is thus a valid alternative to HD for older people with end-stage kidney disease (ESKD) wishing to dialyze at home.


2016 ◽  
Vol 21 (3) ◽  
pp. 409-421 ◽  
Author(s):  
Christina G. Poulsen ◽  
Krista D. Kjaergaard ◽  
Christian D. Peters ◽  
Bente Jespersen ◽  
Jens D. Jensen

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