scholarly journals Variability in hemoglobin levels in hemodialysis patients in the current era: a retrospective cohort study

2017 ◽  
Vol 88 (11) ◽  
pp. 254-265 ◽  
Author(s):  
David T. Gilbertson ◽  
Yan Hu ◽  
Yi Peng ◽  
Bradley J. Maroni ◽  
James B. Wetmore
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Fan-Yu Chen ◽  
Chun-Fan Chen ◽  
Ann Charis Tan ◽  
Chia-Hao Chan ◽  
Fu-An Chen ◽  
...  

AbstractPatients with systemic lupus erythematosus (SLE) have a higher risk of vascular complications. This retrospective cohort study aimed to analyze the differences in the risk of arteriovenous fistula or graft (AVF/AVG) dysfunction in hemodialysis patients with and without SLE from Taiwan’s National Health Insurance Database over a 10-year period. AVF/AVG dysfunction is defined as the occurrence of the first episode of intervention after vascular access creation. A total of 1366 HD patients with SLE had higher incidence rates of AVF/AVG dysfunction than 4098 non-SLE HD patients in the following 4 periods: (1) after 1 year (incidence rates = 15.21% and 13.01%, respectively; subdistribution hazard ratio (SHR) = 1.16; P = 0.007), (2) 1st-to-10th-year period (15.36% and 13.25%; SHR = 1.16; P = 0.007), (3) 5th-to-10th-year period (11.91% and 8.1%; SHR = 1.42; P = 0.003), and (4) overall period (23.53% and 21.66%; SHR = 1.09; P = 0.027). In conclusion, there were significantly higher incidence rates of AVF/AVG dysfunction in SLE patients during the long-term follow-up period. Vascular access function should be monitored regularly by clinical examinations, especially after 1 year and during 5 to 10 years, to improve AVF/AVG patency and dialysis adequacy in SLE patients undergoing maintenance hemodialysis.


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