Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: a case report

2014 ◽  
Vol 81 (02) ◽  
pp. 138-141 ◽  
Author(s):  
Bixia Gao ◽  
Mingxi Li ◽  
Wenli Xia ◽  
Yubin Wen ◽  
Zhen Qu
Keyword(s):  
Case Report ◽  
Basement Membrane ◽  
Iga Nephropathy ◽  
Glomerular Basement Membrane ◽  
Rapidly Progressive Glomerulonephritis

scholarly journals Development of anti-glomerular basement membrane glomerulonephritis during the course of IgA nephropathy: a case report

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Tadasu Kojima ◽  
Go Hirose ◽  
Shuuhei Komatsu ◽  
Taito Oshima ◽  
Kentaro Sugisaki ◽  
...  
Keyword(s):  
Case Report ◽  
Basement Membrane ◽  
Iga Nephropathy ◽  
Glomerular Basement Membrane

scholarly journals Novel therapy for anti-glomerular basement membrane disease with IgA nephropathy: A case report

2016 ◽  
Vol 11 (5) ◽  
pp. 1889-1892 ◽  
Author(s):  
DECHAO XU ◽  
JIANXIANG WU ◽  
JUN WU ◽  
CHENGGANG XU ◽  
YUQIANG ZHANG ◽  
...  
Keyword(s):  
Case Report ◽  
Basement Membrane ◽  
Iga Nephropathy ◽  
Glomerular Basement Membrane ◽  
Novel Therapy

scholarly journals SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Alexander Winkler ◽  
Emanuel Zitt ◽  
Hannelore Sprenger-Mähr ◽  
Afschin Soleiman ◽  
Manfred Cejna ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Plasma Cells ◽  
Rapidly Progressive Glomerulonephritis ◽  
Kidney Injury ◽  
Pulmonary Involvement ◽  
Pulmonary Haemorrhage ◽  
Basement Membranes ◽  
High Avidity ◽  
History Of

Abstract Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage. Recently, an association between COVID-19 and anti-glomerular basement membrane (anti-GBM) disease has been proposed. We report on a patient with recurrence of anti-GBM disease after SARS-CoV-2 infection. Case presentation The 31-year-old woman had a past medical history of anti-GBM disease, first diagnosed 11 years ago, and a first relapse 5 years ago. She was admitted with severe dyspnoea, haemoptysis, pulmonary infiltrates and acute on chronic kidney injury. A SARS-CoV-2 PCR was positive with a high cycle threshold. Anti-GBM autoantibodies were undetectable. A kidney biopsy revealed necrotising crescentic glomerulonephritis with linear deposits of IgG, IgM and C3 along the glomerular basement membrane, confirming a recurrence of anti-GBM disease. She was treated with steroids, plasma exchange and two doses of rituximab. Pulmonary disease resolved, but the patient remained dialysis-dependent. We propose that pulmonary involvement of COVID-19 caused exposure of alveolar basement membranes leading to the production of high avidity autoantibodies by long-lived plasma cells, resulting in severe pulmonary renal syndrome. Conclusion Our case supports the assumption of a possible association between COVID-19 and anti-GBM disease.

scholarly journals Thin basement membrane disease – literature review

2015 ◽  
Vol 84 (3) ◽  
pp. 201-204
Author(s):  
Jakub Żurawski
Keyword(s):  
Electron Microscope ◽  
Basement Membrane ◽  
Literature Review ◽  
Iga Nephropathy ◽  
Glomerular Basement Membrane ◽  
Alport Syndrome ◽  
Clinical Course ◽  
Renal Diseases ◽  
Renal Lithiasis ◽  
Thin Basement Membrane Disease

Initially, the thin glomerular basement membrane disease was called “a gentle and curable hemorrhagic nephritis”. The thin basement membrane disease has been finally characterized at the beginning of 1970s. This is when the connection between previously clinically described gentle microhematuria and significant thinning of glomerular basement membrane discovered during examination under the electron-microscope has been established. Ultimately, the disease has been described as a condition characterized with a diverse clinical course, usually mild, but sometimes progressive. It is a family conditioned disease, but it also appears sporadically and concerns at least 1% of the population. It has also been stated that it is one of the most frequent renal diseases, enumerated directly after changes caused by infections, hypertension and renal lithiasis. This particular disease is diagnosed more often than IgA nephropathy and Alport syndrome, which are also associated with haematuria or microhematuria.

scholarly journals Anti-glomerular basement membrane glomerulonephritis in an HIV positive patient: case report

2006 ◽  
Vol 10 (1) ◽  
pp. 55-58 ◽  
Author(s):  
Eduardo José Bellotto Monteiro ◽  
Daiane Caron ◽  
Carlos Alberto Balda ◽  
Marcello Franco ◽  
Aparecido Bernardo Pereira ◽  
...  
Keyword(s):  
Case Report ◽  
Basement Membrane ◽  
Glomerular Basement Membrane ◽  
Positive Patient ◽  
Hiv Positive ◽  
Patient Case
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