Arbeitsplatzbezogener Inhalationstest (AIT) – Specific Inhalation Challenge (SIC)

Allergologie ◽  
2021 ◽  
Vol 44 (10) ◽  
pp. 773-794
Author(s):  
A.M. Preisser ◽  
D. Koschel ◽  
R. Merget ◽  
D. Nowak ◽  
M. Raulf ◽  
...  
Keyword(s):  
Specific Inhalation Challenge ◽  
Inhalation Challenge

scholarly journals Pulmonary Function Testing in Work-Related Asthma: An Overview from Spirometry to Specific Inhalation Challenge

2021 ◽  
Vol 18 (5) ◽  
pp. 2325
Author(s):  
Mathias Poussel ◽  
Isabelle Thaon ◽  
Emmanuelle Penven ◽  
Angelica I. Tiotiu
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Objective Evaluation ◽  
Pulmonary Function Testing ◽  
Initial Assessment ◽  
Work Related ◽  
Specific Inhalation Challenge ◽  
Occupational Setting ◽  
Inhalation Challenge ◽  
Function Testing

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.

Specific Inhalation Challenge in Persulfate Asthma

2015 ◽  
pp. 85-91 ◽  
Author(s):  
O. Hagemeyer ◽  
E. Marek ◽  
V. van Kampen ◽  
I. Sander ◽  
M. Raulf ◽  
...  
Keyword(s):  
Specific Inhalation Challenge ◽  
Inhalation Challenge

scholarly journals 1512 Asthma control and work disability in subjects previously evaluated for work-related asthma with specific inhalation challenge

2018 ◽  
Author(s):  
Ilenia Folletti ◽  
Umberto Giovannelli ◽  
Giulia Paolocci ◽  
Marco dell’Omo ◽  
Angela Gambelunghe ◽  
...  
Keyword(s):  
Asthma Control ◽  
Work Disability ◽  
Work Related ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge

Can persulfates cause hypersensitivity pneumonitis? A report of specific inhalation challenge test in 42 hairdressers

2020 ◽  
Author(s):  
Jens-Tore Granslo ◽  
Jorunn Kirkeleit ◽  
Stein Håkon Låstad Lygre ◽  
William Horsnell ◽  
Thomas Blix Grydeland ◽  
...  
Keyword(s):  
Hypersensitivity Pneumonitis ◽  
Challenge Test ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge

Specific inhalation challenge with flour induced release of brain-derived neurotrophic factor in nasal fluid

2013 ◽  
Vol 4 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Roberto Castano ◽  
Melanie Welman ◽  
Carole Trudeau ◽  
Lucero Castellanos ◽  
Karim Maghni ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Specific Inhalation Challenge ◽  
Inhalation Challenge ◽  
Nasal Fluid
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