scholarly journals SIMULTANEOUS PRESENTATION OF A PATIENT WITH ACUTE CORONARY SYNDROME, ACUTE LIMB ISCHEMIA AND DEEP VENOUS THROMBOSIS COMPLICATED BY PULMONARY EMBOLISM IN EMERGENCY ROOM: A CASE REPORT

2021 ◽  
Keyword(s):  
Pulmonary Embolism ◽  
Acute Coronary Syndrome ◽  
Case Report ◽  
Venous Thrombosis ◽  
Emergency Room ◽  
Deep Venous Thrombosis ◽  
Limb Ischemia ◽  
Simultaneous Presentation ◽  
Acute Limb Ischemia ◽  
Coronary Syndrome

scholarly journals Concomitant Acute Limb Ischemia and Pulmonary Embolism in the Course of SARS-CoV-2 Infection: Case Report

2021 ◽  
Author(s):  
Mahassine El harras ◽  
AMAL ELOUARRADI ◽  
SALMA ABDELADIM ◽  
FATIMAZAHRA MERZOUK ◽  
MERYEM KASSIMI ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Case Report ◽  
Venous Thrombosis ◽  
Initial Treatment ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Significant Morbidity ◽  
Mild Form ◽  
Thrombotic Complications ◽  
Prophylactic Anticoagulation

Abstract Background: The new 2019 coronavirus disease (COVID-19) is associated with significant morbidity and mortality. Thrombotic complications are increasingly recognized as an important part of this disease. Thromboprophylaxis with anti-platelet drugs and anticoagulants are recommended in the initial treatment of the disease.Case presentation: We report the case of a patient hospitalized for a mild form of COVID19 pneumonia, who was admitted, one month later, acute limb ischemia and pulmonary embolism despite antithrombotic prophylaxis. Conclusion: Most reported cases are either arterial or venous thrombosis. The concomitant combination of arterial and venous thrombosis is rarely reported. The prophylactic anticoagulation strategy in the SARS- Cov 2 infection is steel not well established.

scholarly journals Case Report: Vena Cava Filter Implantation to Prevent Lethal Pulmonary Embolism in Patients with Deep Venous Thrombosis after Transfer of Acetabulum Operation.

2000 ◽  
Vol 49 (2) ◽  
pp. 335-344
Author(s):  
Kenji Sakai ◽  
Yasuo Noguchi ◽  
Seiya Jingushi ◽  
Toshihide Shuto ◽  
Yasuharu Nakashima ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Case Report ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Vena Cava ◽  
Vena Cava Filter

scholarly journals O23 Pulmonary emboli in a teenager with GPA: management dilemmas

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Sam Deepak ◽  
Satyapal Rangaraj ◽  
Kishore Warrier
Keyword(s):  
Pulmonary Embolism ◽  
Case Report ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Pulmonary Vein ◽  
Inflammatory Markers ◽  
Intravenous Cyclophosphamide ◽  
Vascular Events ◽  
Lung Lesions ◽  
Induction Regimen

Abstract Case report - Introduction 15 year old girl with the diagnosis of granulomatosis polyangiitis (GPA) managed with induction regimen of intravenous cyclophosphamide and whilst on maintenance mycophenolate mofetil (MMF) developed multiple cavitating lung lesions with the large cavity abutting pulmonary vein and bilateral segmental pulmonary embolism (PE) posing complex management dilemmas. Case report - Case description 15-year-old girl presented with being unwell for 3 months with malaise, lethargy, joint pains, significant weight loss (10 kg), mouth ulcer and significant hearing loss. Investigations showed anaemia, raised inflammatory markers, and impaired kidney function (estimated glomerular filtration rate eGFR 40). Her ANCA was positive, hearing test showed significant mixed hearing loss and CXR was normal. The renal biopsy confirmed pauci-immune ANCA associated glomerulonephritis with 70% crescents. She was initially managed with intravenous pulse of steroids followed by oral weaning regime, double filtration plasmapheresis and commenced on induction regimen of intravenous cyclophosphamide. She received 6 doses of cyclophosphamide 500 mg/m2 and following good recovery with normalising kidney function; was commenced on maintenance MMF. At this point she developed new onset earache, sore throat, and hoarseness of voice with raised inflammatory markers and worsening symptoms despite antibiotics. This was presumed to a flare of vasculitis and hence was given further pulse of steroids and increased the dose of MMF. The ENT assessment did not reveal any subglottic stenosis. After few weeks, symptoms recurred with cough/hoarseness of voice and associated tiredness. Bloods showed raised inflammatory markers; CXR revealed cavitating lung lesions and a CT chest was arranged. CT chest showed apical sub pleural lung nodule and a large thick-walled cavity measuring 6.6x 4.4 cm abutting the pulmonary vein on the right side and bilateral segmental pulmonary emboli. The child was systemically stable with no respiratory distress and oxygen saturations were 100% in air. Case report - Discussion The management of GPA was further complicated by the pulmonary embolism and cavitating lung lesions abutting pulmonary vein. The management included escalation of immunosuppression with pulse of steroids, further dose of cyclophosphamide and commence Rituximab .The key challenges with the immediate management were risk of bleeding associated with the anticoagulation, treating the pulmonary embolism, risk of diffuse alveolar haemorrhage and managing the patient in a safe setting equipped with all the expertise required. The child was screened for cardiolipin antibodies on multiple occasions and these were negative. An ECHO was done to look for evidence of clot at the end of central line tip, but this was normal. Deep venous thrombosis of legs was ruled out by Doppler scanning. There was no clear source of emboli identified. Although there is emerging evidence for increased incidence of vascular events in GPA adult patients, the data on vascular events in children with GPA is scarce. Merkel and co-workers reported a high occurrence of pulmonary embolism (PE) and deep venous thrombosis (DVT) among GPA patients included in a randomized therapeutic trial (WeCLOT study) 1 .FAURSCHOU et al. reported that GPA was associated with a much lower relative risk of stroke than of pulmonary embolism and deep venous thrombosis; the risk of venous thromboembolic events among GPA patients was increased during early as well as late follow up periods. Currently there are no significant data on the use of antiplatelet and/or anticoagulant therapy in AAV. Following extensive multidisciplinary discussion with respiratory, haematology, cardiology, cardiothoracic surgical and paediatric intensive care teams, and the child was anticoagulated with close monitoring in paediatric high dependency unit and immunosuppression escalated alongside. Case report - Key learning points  This case highlights the risk of thromboembolic events in children with GPAProposed mechanisms in the literature for thrombosis in vasculitis at molecular level would probably explain the episode in the absence of source identifiedMultidisciplinary team approach is crucial for management of complex patientsThere were few challenges due to geographical location of the patient and the regional variation of subspecialty cover provided for their local District General HospitalFor discussion- Role of Rituximab early in GPA?

scholarly journals Deep Venous Thrombosis and Pulmonary Embolism in a Patient with Multiple Sclerosis: Case Report

2017 ◽  
Vol 26 (2) ◽  
pp. 79-84
Author(s):  
Arzu YAZAL ERDEM ◽  
Dilek KAÇAR ◽  
Neşe YARALI ◽  
Selcen BAĞCI ◽  
Bahattin TUNÇ
Keyword(s):  
Multiple Sclerosis ◽  
Pulmonary Embolism ◽  
Case Report ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Multiple Sclerosis Case

scholarly journals Concomitant Acute Limb Ischemia and Pulmonary Embolism in the Course of SARS-CoV-2 Infection: Case Report

2021 ◽  
Vol 6 (11) ◽  
pp. 831-834
Author(s):  
Mahassine El Harras ◽  
Amal Elouarradi ◽  
Salma Abdeladim ◽  
Fatimazahra Merzouk ◽  
Meryem Kassimi ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Venous Thrombosis ◽  
Limb Ischemia ◽  
Acute Limb Ischemia ◽  
Significant Morbidity ◽  
Mild Form ◽  
Case Presentation ◽  
Disease Case ◽  
Thrombotic Complications ◽  
Prophylactic Anticoagulation

Background: The new 2019 coronavirus disease (COVID-19) is associated with significant morbidity and mortality. Thrombotic complications are increasingly recognized as an important part of this disease. Thromboprophylaxis with anti-platelet drugs and anticoagulants are recommended in the initial treatment of the disease. Case presentation: We report the case of a patient hospitalized for a mild form of COVID19 pneumonia, who was admitted, one month later, acute limb ischemia and pulmonary embolism despite antithrombotic prophylaxis. Conclusion: Most reported cases are either arterial or venous thrombosis. The concomitant combination of arterial and venous thrombosis is rarely reported. The prophylactic anticoagulation strategy in the SARS- Cov 2 infection is still not well established.

scholarly journals Association of pulmonary embolism and acute coronary syndrome during COVID-19 infection: Case report and a brief review

2021 ◽  
pp. 103152
Author(s):  
Abdelaziz boudihi ◽  
Charmake Derar ◽  
Mosaab Mazouzi ◽  
Nabila ismaili ◽  
Noha el ouafi
Keyword(s):  
Pulmonary Embolism ◽  
Acute Coronary Syndrome ◽  
Case Report ◽  
Coronary Syndrome

scholarly journals Can’t Dissolve Me Now: A COVID-19 Provoked Venous Thromboembolism Breaks Through Apixaban: Case Report

2021 ◽  
Vol 2 (5) ◽  
pp. 202-205
Author(s):  
Alexander Arena ◽  
Ahmad Hussein ◽  
Ellen Kurkowski ◽  
Ellen Kurkowski ◽  
Miriam Kulkarni
Keyword(s):  
Emergency Department ◽  
Pulmonary Embolism ◽  
Case Report ◽  
Venous Thromboembolism ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Optimal Dosage ◽  
History Of

Introduction: Coronavirus disease 2019 (COVID-19) is a multisystem process with a growing evidence of its endotheliopathy effects, with subsequent hypercoagulability states. Case Report: WWe present an emergency department case of a COVID-19-provoked deep venous thrombosis and pulmonary embolism without a history of venous thromboembolism (VTE), with extension of the VTE despite adherence to apixaban. Conclusion: This case demonstrates the importance of further research and protocols for optimal dosage and treatment to prevent worsening VTE in COVID-19 patients.

GLYCEMIC STATUS AND SHORT TERM OUTCOME IN PATIENTS WITH DIABETES MELLITUS ADMITTED WITH ACUTE MACROVASCULAR COMPLICATION IN A TERTIARY CARE HOSPITAL IN INDIA

2021 ◽  
pp. 31-33
Author(s):  
Soumyajit Mukherjee ◽  
Prabir Kumar Kundu ◽  
Indira Maisnam ◽  
Apurba Kumar Mukherjee
Keyword(s):  
Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Cerebrovascular Accident ◽  
Limb Ischemia ◽  
Diabetic Patients ◽  
Acute Limb Ischemia ◽  
Care Hospital ◽  
Medical College ◽  
Coronary Syndrome ◽  
Hospitalized Patient

Introduction: Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. Over the past two decades the prevalence of diabetes has risen from an estimated 30 million cases in 1985 to 415 million in 2017. Aims & objectives: To study HbA1c and other biochemical & clinical parameters of acute ischemic cerebrovascular accident, acute coronary syndrome and acute limb ischemia in diabetic patients. Specific objectives: · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute ischemic cerebrovascular accident. · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute coronary syndrome · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute limb ischemia · To study correlation between HbA1C and 72 hours mortality of patients with acute macrovascular events among diabetics. Materials & methods: Department of general medicine, R.G.Kar Medical College and Hospital.Cases were selected from medicine inpatients department of R.G.Kar Medical College and Hospital. 1st July, 2018-30th June 2019. This is an observational prospective study Conclusion: In our study we found that higher HbA1C is associated with statistically signicant increase in 72 hour mortality in patients with acute ischemic stroke and trend of increased mortality (though not statistically signicant) in patients (p=0.0002 & 0.056 respectively)

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