scholarly journals Neospora caninum and Wildlife

2013 ◽  
Vol 2013 ◽  
pp. 1-23 ◽  
Author(s):  
Sonia Almería
Keyword(s):  
Life Cycle ◽  
Current Knowledge ◽  
Neospora Caninum ◽  
Control Measures ◽  
Sylvatic Cycle ◽  
Zoo Animals ◽  
Wild Dogs ◽  
Cattle Farms ◽  
Important Disease

Bovine neosporosis caused by Neospora caninum is among the main causes of abortion in cattle nowadays. At present there is no effective treatment or vaccine. Serological evidence in domestic, wild, and zoo animals indicates that many species have been exposed to this parasite. However, many aspects of the life cycle of N. caninum are unknown and the role of wildlife in the life cycle of N. caninum is still not completely elucidated. In North America, there are data consistent with a sylvatic cycle involving white tailed-deer and canids and in Australia a plausible sylvatic cycle could be occurring between wild dogs and their macropod preys. In Europe, a similar sylvatic cycle has not been established but is very likely. The present review is a comprehensive and up to date summary of the current knowledge on the sylvatic cycle of N. caninum, species affected and their geographical distribution. These findings could have important implications in both sylvatic and domestic cycles since infected wildlife may influence the prevalence of infection in cattle farms in the same areas. Wildlife will need to be taken into account in the control measures to reduce the economical losses associated with this important disease in cattle farms.

scholarly journals Biosurveillance of Selected Pathogens with Zoonotic Potential in a Zoo

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 428
Author(s):  
Pavel Kvapil ◽  
Joško Račnik ◽  
Marjan Kastelic ◽  
Jiřina Marková ◽  
Jean-Benjamin Murat ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Neospora Caninum ◽  
Field Mouse ◽  
Wild Rodents ◽  
Cygnus Olor ◽  
Multiplex Pcr Assay ◽  
Significant Difference ◽  
Zoo Animals ◽  
Mute Swans

Monitoring of infectious diseases is one of the most important pillars of preventive medicine in zoos. Screening for parasitic and bacterial infections is important to keep animals and equipment safe from pathogens that may pose a risk to animal and human health. Zoos usually contain many different animal species living in proximity with people and wild animals. As an epidemiological probe, 188 animals (122 mammals, 65 birds, and one reptile) from a zoo in Slovenia were examined for selected pathogens. Antibodies to Toxoplasma gondii and Neospora caninum were detected by ELISA in 38% (46/122) and 3% (4/122) of mammals, and in 0% (0/64) and 2% (1/57) of birds, respectively; the reptile (0/1) was negative. A statistically significant difference in T. gondii prevalence was found in Carnivora compared to Cetartiodactyla and primate antibodies to Encephalitozoon cuniculi were detected by IFAT in 44% (52/118) of mammals and 20% (11/56) of birds, respectively; the reptile (0/1) was negative. Herbivores had a higher chance of being infected with E. cuniculi compared to omnivores. Antibodies to Chlamydia abortus and Coxiella burnetii were not detected in any of the 74 tested zoo animals. The sera of 39 wild rodents found in the zoo were also examined; they were negative for all three parasites. The parasite T. gondii was detected by PCR in the tissue of two mute swans (Cygnus olor), three eastern house mice (Mus musculus), one yellow-necked field mouse (Apodemus flavicollis), and one striped field mouse (A. agrarius). Positive samples were genotyped by a single multiplex PCR assay using 15 microsatellite markers; one sample from a mute swan was characterized as type II. This micro-epidemiological study offers a better understanding of pathogens in zoo animals and an understanding of the role of zoos in biosurveillance.

scholarly journals Evaluation of Neospora caninum-Associated Abortion in a Seroepidemiological Study of Cattles Using IFAT Method

2020 ◽  
Vol 1 (1) ◽  
pp. 7-10
Author(s):  
Seyed Razi Bahavarnia ◽  
Pedram Ahli ◽  
Arash Rasouli
Keyword(s):  
Neospora Caninum ◽  
Farming System ◽  
Chi Square ◽  
Related Risk ◽  
Coccidian Parasites ◽  
Chi Square Test ◽  
Relationship Of ◽  
Cattle Farms ◽  
The Relationship

Background: Neospora caninum is a cyst forming coccidian parasites and one of the important factors in abortion of cows and neurologic disease in dogs around the world. This study was conducted to investigate the seroprevalence of N. caninum in dairy cows of Tabriz city using immunofluorescence method and related risk factors. Methods: In this study conducted in 2018, 100 samples from industrial cattle farms and 100 samples from traditional cattle farms of Tabriz were randomly collected. By fixing tachyzoites cultured in a culture medium, the kit was prepared in this study and the slides were examined by fluorescence microscopy (Zeiss). The results obtained in relation to the study variables (type of farming system, age, contact with dogs, and abortion history) were analyzed using SPSS software and chi-square test. Results: Neospora caninum antibodies were detected in 33 samples (16.5%). The relationship of positive serums with abortion and contact with dogs was significant statistically (P<0.05). Conclusions: Due to the significant relationship of infection rate in cows with abortion history and contact with dogs, further studies are needed to determine the exact role of Neospora in abortion of cows.

scholarly journals Epidemiology and Control of Neosporosis and Neospora caninum

2007 ◽  
Vol 20 (2) ◽  
pp. 323-367 ◽  
Author(s):  
J. P. Dubey ◽  
G. Schares ◽  
L. M. Ortega-Mora
Keyword(s):  
Life Cycle ◽  
New Genus ◽  
Neospora Caninum ◽  
Protozoan Parasite ◽  
Zoonotic Potential ◽  
Human Tissues ◽  
New Genus And Species ◽  
Serious Disease ◽  
And Control

SUMMARY Neospora caninum is a protozoan parasite of animals. Until 1988, it was misidentified as Toxoplasma gondii. Since its first recognition in dogs in 1984 and the description of the new genus and species Neospora caninum in 1988, neosporosis has emerged as a serious disease of cattle and dogs worldwide. Abortions and neonatal mortality are a major problem in livestock operations, and neosporosis is a major cause of abortion in cattle. Although antibodies to N. caninum have been reported, the parasite has not been detected in human tissues. Thus, the zoonotic potential is uncertain. This review is focused mainly on the epidemiology and control of neosporosis in cattle, but worldwide seroprevalences of N. caninum in animals and humans are tabulated. The role of wildlife in the life cycle of N. caninum and strategies for the control of neosporosis in cattle are discussed.

scholarly journals Clostridium perfringens: a review of the disease in pigs, horses and broiler chickens

2015 ◽  
Vol 45 (6) ◽  
pp. 1027-1034 ◽  
Author(s):  
Rodrigo Otávio Silveira Silva ◽  
Carlos Augusto Oliveira Junior ◽  
Roberto Maurício Carvalho Guedes ◽  
Francisco Carlos Faria Lobato
Keyword(s):  
Clostridium Perfringens ◽  
Broiler Chickens ◽  
Current Knowledge ◽  
Predisposing Factors ◽  
Enteric Pathogen ◽  
Control Measures ◽  
Gram Positive

Clostridium perfringens is a gram-positive, anaerobic, fermentative, spore-forming bacillus that may be found in the environment but is more commonly found as part of the microbiota of humans and animals. The bacterium is considered a common enteric pathogen; however, the pathogenesis and predisposing factors of the disease can differ among species. Therefore, specific studies are necessary for understanding the role of this pathogen, how to diagnose it and which control measures are applicable. The aim of this paper is to review the current knowledge regarding C. perfringens infections in pigs, horses and broiler chickens

scholarly journals Detection of Neospora Caninum DNA in Wild Birds from Italy

Pathogens ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 202 ◽  
Author(s):  
Simona Nardoni ◽  
Alessandro Poli ◽  
Ilaria Varvaro ◽  
Guido Rocchigiani ◽  
Renato Ceccherelli ◽  
...  
Keyword(s):  
Life Cycle ◽  
Neospora Caninum ◽  
Present Report ◽  
Epidemiological Data ◽  
Avian Species ◽  
Water Birds ◽  
Serological Data ◽  
State Of Art

The role of avian species in the Neospora caninum life cycle has not been completely elucidated, and epidemiological data from Europe are scant. The aim of the present report was to evaluate the presence of N. caninum DNA in the tissues of 302 birds belonging to different avian species, along with IFAT titers. Forty-two out of the 302 birds (13.9%) showed low serological titers (1/50 and 1/100) against N. caninum. These data, positive for 31 animals (10.3%), were corroborated by PCR. Twenty-two hearts and eighteen brains scored positive, while nine subjects resulted had parasite DNA both in their hearts and brains. Serological data showed significantly higher results in waterfowl in respect to non-waterfowl avian species. This finding indicates a higher exposure of water birds to the parasite. These avian species, in fact, which feed directly from soil and/or water, are prone to ingest oocysts excreted by final canid hosts. The present study adds information to the state of art of N. caninum epidemiology in Italy, even if more investigations using bio-assays are needed to allow for a serological/parasitological follow-up to evaluate the real impact of the avian species in maintaining the parasite in main reservoirs.

scholarly journals Autophagy in HCV Infection: Keeping Fat and Inflammation at Bay

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Tiziana Vescovo ◽  
Giulia Refolo ◽  
Alessandra Romagnoli ◽  
Fabiola Ciccosanti ◽  
Marco Corazzari ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Life Cycle ◽  
Liver Disease ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Viral Persistence ◽  
Hcv Infection ◽  
Lipid Homeostasis ◽  
Specific Host

Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease. Viral persistence and pathogenesis rely mainly on the ability of HCV to deregulate specific host processes, including lipid metabolism and innate immunity. Recently, autophagy has emerged as a cellular pathway, playing a role in several aspects of HCV infection. This review summarizes current knowledge on the molecular mechanisms that link the HCV life cycle with autophagy machinery. In particular, we discuss the role of HCV/autophagy interaction in dysregulating inflammation and lipid homeostasis and its potential for translational applications in the treatment of HCV-infected patients.

scholarly journals The COVID-19 epidemic, its mortality, and the role of non-pharmaceutical interventions

2020 ◽  
Vol 9 (3) ◽  
pp. 204-208 ◽  
Author(s):  
Niel Hens ◽  
Pascal Vranck ◽  
Geert Molenberghs
Keyword(s):  
Current Knowledge ◽  
Control Measures ◽  
Economic Downturn ◽  
Key Factors ◽  
Primary Case ◽  
Infectious Disease Outbreak ◽  
Curve Estimation ◽  
Epidemic Curve ◽  
Near Future

COVID-19 has developed into a pandemic, hitting hard on our communities. As the pandemic continues to bring health and economic hardship, keeping mortality as low as possible will be the highest priority for individuals; hence governments must put in place measures to ameliorate the inevitable economic downturn. The course of an epidemic may be defined by a series of key factors. In the early stages of a new infectious disease outbreak, it is crucial to understand the transmission dynamics of the infection. The basic reproduction number ( R0), which defines the mean number of secondary cases generated by one primary case when the population is largely susceptible to infection (‘totally naïve’), determines the overall number of people who are likely to be infected, or, more precisely, the area under the epidemic curve. Estimation of changes in transmission over time can provide insights into the epidemiological situation and identify whether outbreak control measures are having a measurable effect. For R0 > 1, the number infected tends to increase, and for R0 < 1, transmission dies out. Non-pharmaceutical strategies to handle the epidemic are sketched and based on current knowledge, the current situation is sketched and scenarios for the near future discussed.

Mesophyll conductance: the leaf corridors for photosynthesis

2020 ◽  
Vol 48 (2) ◽  
pp. 429-439 ◽  
Author(s):  
Jorge Gago ◽  
Danilo M. Daloso ◽  
Marc Carriquí ◽  
Miquel Nadal ◽  
Melanie Morales ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Main Role ◽  
Mesophyll Conductance ◽  
Future Studies ◽  
Cell Structures ◽  
Leaf Tissues ◽  
Change Framework ◽  
Chloroplast Stroma

Besides stomata, the photosynthetic CO2 pathway also involves the transport of CO2 from the sub-stomatal air spaces inside to the carboxylation sites in the chloroplast stroma, where Rubisco is located. This pathway is far to be a simple and direct way, formed by series of consecutive barriers that the CO2 should cross to be finally assimilated in photosynthesis, known as the mesophyll conductance (gm). Therefore, the gm reflects the pathway through different air, water and biophysical barriers within the leaf tissues and cell structures. Currently, it is known that gm can impose the same level of limitation (or even higher depending of the conditions) to photosynthesis than the wider known stomata or biochemistry. In this mini-review, we are focused on each of the gm determinants to summarize the current knowledge on the mechanisms driving gm from anatomical to metabolic and biochemical perspectives. Special attention deserve the latest studies demonstrating the importance of the molecular mechanisms driving anatomical traits as cell wall and the chloroplast surface exposed to the mesophyll airspaces (Sc/S) that significantly constrain gm. However, even considering these recent discoveries, still is poorly understood the mechanisms about signaling pathways linking the environment a/biotic stressors with gm responses. Thus, considering the main role of gm as a major driver of the CO2 availability at the carboxylation sites, future studies into these aspects will help us to understand photosynthesis responses in a global change framework.

Prospective Memory Development Across the Lifespan

2020 ◽  
Vol 25 (3) ◽  
pp. 162-173 ◽  
Author(s):  
Sascha Zuber ◽  
Matthias Kliegel
Keyword(s):  
Prospective Memory ◽  
Healthy Aging ◽  
Present Model ◽  
Current Knowledge ◽  
Well Being ◽  
The Elderly ◽  
Cognitive Factors ◽  
Everyday Functioning ◽  
Integrative Framework

Abstract. Prospective Memory (PM; i.e., the ability to remember to perform planned tasks) represents a key proxy of healthy aging, as it relates to older adults’ everyday functioning, autonomy, and personal well-being. The current review illustrates how PM performance develops across the lifespan and how multiple cognitive and non-cognitive factors influence this trajectory. Further, a new, integrative framework is presented, detailing how those processes interplay in retrieving and executing delayed intentions. Specifically, while most previous models have focused on memory processes, the present model focuses on the role of executive functioning in PM and its development across the lifespan. Finally, a practical outlook is presented, suggesting how the current knowledge can be applied in geriatrics and geropsychology to promote healthy aging by maintaining prospective abilities in the elderly.

ASPECTS IN BUILDING A COMPANY WEB-SITE AND ITS ROLE FOR THE DEVELOPMENT OF BUSINESS

2018 ◽  
pp. 117-124
Author(s):  
Petar Halachev ◽  
Victoria Radeva ◽  
Albena Nikiforova ◽  
Miglena Veneva
Keyword(s):  
Life Cycle ◽  
Web Site ◽  
The Internet ◽  
A Company ◽  
The Web ◽  
Design Construction ◽  
Made In ◽  
Site Types

This report is dedicated to the role of the web site as an important tool for presenting business on the Internet. Classification of site types has been made in terms of their application in the business and the types of structures in their construction. The Models of the Life Cycle for designing business websites are analyzed and are outlined their strengths and weaknesses. The stages in the design, construction, commissioning, and maintenance of a business website are distinguished and the activities and requirements of each stage are specified.

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