scholarly journals An Overview of the Malaria Control Programme in Zambia

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Emmanuel Chanda ◽  
Mulakwa Kamuliwo ◽  
Richard W. Steketee ◽  
Michael B. Macdonald ◽  
Olusegun Babaniyi ◽  
...  
Keyword(s):  
Malaria Control ◽  
National Development ◽  
National Malaria Control Programme ◽  
Universal Coverage ◽  
Control Programme ◽  
Malaria Control Programme ◽  
Evidence Based ◽  
Malaria Surveillance ◽  
High Coverage ◽  
The Government

The Zambian national malaria control programme has made great progress in the fight against Malaria. The country has solid, consistent, and coordinated policies, strategies, and guidelines for malaria control, with government prioritizing malaria in both the National Health Strategic Plan and the National Development Plan. This has translated into high coverage of proven and effective key preventive, curative, and supportive interventions with concomitant marked reduction in both malaria cases and deaths. The achievements attained can be attributed to increased advocacy, communication and behaviour changes, efficient partnership coordination including strong community engagement, increased financial resources, and evidence-based deployment of key technical interventions in accordance with the national malaria control programme policy and strategic direction. The three-ones strategy has been key for increased and successful public-private sector partner coordination, strengthening, and mobilization. However, maintaining the momentum and the gains is critical as the programme strives to achieve universal coverage of evidence-based and proven interventions. The malaria control programme’s focus is to maintain the accomplishments, by mobilizing more resources and partners, increasing the government funding towards malaria control, scaling up and directing interventions based on epidemiological evidence, and strengthen active malaria surveillance and response to reduce transmission and to begin considering elimination.

scholarly journals Multiple insecticide resistance target sites in adult field strains of An. gambiae (s.l.) from southeastern Senegal

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
El hadji Diouf ◽  
El hadji Amadou Niang ◽  
Badara Samb ◽  
Cheikh Tidiane Diagne ◽  
Mbaye Diouf ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Indoor Residual Spraying ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Molecular Techniques ◽  
Target Site ◽  
Malaria Control Programme ◽  
Insecticide Susceptibility ◽  
High Coverage ◽  
Pyrethroid Insecticides

Abstract Background High coverage of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of vector control strategy in Senegal where insecticide resistance by the target vectors species is a great of concern. This study explores insecticide susceptibility profile and target-site mutations mechanisms within the Anophelesgambiae complex in southeastern Senegal. Methods Larvae of Anopheles spp. were collected in two sites from southeastern Senegal Kedougou and Wassadou/Badi in October and November 2014, and reared until adult emergence. Wild F0 adult mosquitoes were morphologically identified to species. Susceptibility of 3–5-day-old An. gambiae (s.l.) samples to 11 insecticides belonging to the four insecticide classes was assessed using the WHO insecticide susceptibility bioassays. Tested samples were identified using molecular techniques and insecticide resistance target-site mutations (kdr, ace-1 and rdl) were determined. Results A total of 3742 An.gambiae (s.l.) were exposed to insecticides (2439 from Kedougou and 1303 from Wassadou-Badi). Tests with pyrethroid insecticides and DDT showed high level of resistance in both Kedougou and Wassadou/Badi. Resistance to pirimiphos-methyl and malathion was not detected while resistance to bendoicarb and fenitrothion was confirmed in Kedougou. Of the 745 specimens of An.gambiae (s.l.) genotyped, An.gambiae (s.s.) (71.6%) was the predominant species, followed by An.arabiensis (21.7%), An.coluzzii (6.3%) and hybrids (An. gambiae (s.s.)/An.coluzzii; 0.4%). All target site mutations investigated (Vgsc-1014F, Vgsc-1014S, Ace-1 and Rdl) were found at different frequencies in the species of the Anophelesgambiae complex. Vgsc-1014F mutation was more frequent in An.gambiae (s.s.) and An.coluzzii than An.arabiensis. Vgsc-1014S was present in An.gambiae (s.l.) populations in Wassadou but not in Kedougou. Ace-1 and rdl mutations were more frequent in An.gambiae (s.s.) in comparison to An.arabiensis and An.coluzzii. Conclusions Resistance to all the four insecticide classes tested was detected in southeastern Senegal as well as all target site mutations investigated were found. Data will be used by the national Malaria Control Programme.

scholarly journals Long-term Transmission Patterns and Public Health Policies Leading to Malaria Elimination in Panamá

2020 ◽  
Author(s):  
Lisbeth Hurtado ◽  
Alberto Cumbreras ◽  
Chystrie Rigg ◽  
Milixa Perea ◽  
Ana María Santamaría ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Retrospective Analysis ◽  
Malaria Control ◽  
Time Series Data ◽  
Southern Oscillation ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Series Data ◽  
Malaria Control Programme

Abstract Background: The present study provides a countrywide perspective of the malaria situation in Panama over a long-term framework, with the purpose of identifying historical malaria resurgence events and their potential causes.Methods: A descriptive-ecological study was conducted by analyzing demographic and epidemiological annual malaria time series data in Panamá (1884 – 2019) using several data sources. Malaria intensity indicators were calculated during the study period. We also analyze the effects of El Niño Southern Oscillation on malaria transmission using a retrospective analysis of malaria cases between 1957 and 2019.Results: Several factors were identified responsible for malaria resurgence in Panama, mostly related with Malaria Control Programme weakening. During the past 20 years (2000 – 2019) malaria has progressively increased its prevalence within indigenous settlements, with a predominance of male cases and a high proportion (15% of total cases) in children less than 5 years old. During this period a significant and increasing proportion of the P. falciparum total cases were imported. Our retrospective analysis (1957 - 2019) evidenced that ENSO has a significant impact on malaria transmission dynamics in Panama.Conclusions: Data analysis confirmed that although authorities have been successful in focalizing malaria transmission in the country, there are still neglected issues to be solved and important intercultural barriers that need to be addressed in order to achieve elimination of the disease by 2022. This information will be useful for targeting strategies by the National Malaria Control Programme.

scholarly journals Long-term transmission patterns and public health policies leading to malaria elimination in Panamá

2020 ◽  
Author(s):  
Lisbeth Hurtado ◽  
Alberto Cumbrera ◽  
Chystrie Rigg ◽  
Milixa Perea ◽  
Ana María Santamaría ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Retrospective Analysis ◽  
Malaria Control ◽  
Time Series Data ◽  
Southern Oscillation ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Series Data ◽  
Malaria Control Programme

Abstract Background: The present study provides a countrywide perspective of the malaria situation in Panama over a long-term framework, with the purpose of identifying historical malaria resurgence events and their potential causes. Methods: A descriptive-ecological study was conducted by analyzing demographic and epidemiological annual malaria time series data in Panamá (1884 – 2019) using several data sources. Malaria intensity indicators were calculated during the study period. We also analyze the effects of El Niño Southern Oscillation on malaria transmission using a retrospective analysis of malaria cases between 1957 and 2019. Results: Several factors were identified responsible for malaria resurgence in Panama, mostly related with Malaria Control Programme weakening. During the past 20 years (2000 – 2019) malaria has progressively increased its prevalence within indigenous settlements, with a predominance of male cases and a high proportion (15% of total cases) in children less than 5 years old. During this period a significant and increasing proportion of the P. falciparum total cases were imported. Our retrospective analysis (1957 - 2019) evidenced that ENSO has a significant impact on malaria transmission dynamics in Panama. Conclusions: Data analysis confirmed that although authorities have been successful in focalizing malaria transmission in the country, there are still neglected issues to be solved and important intercultural barriers that need to be addressed in order to achieve elimination of the disease by 2022. This information will be useful for targeting strategies by the National Malaria Control Programme.

scholarly journals Long-Term Transmission Patterns and Public Health Policies Leading to Malaria Elimination in Panamá

2020 ◽  
Author(s):  
Lisbeth Hurtado ◽  
Alberto Cumbrera ◽  
Chystrie Rigg ◽  
Milixa Perea ◽  
Ana María Santamaría ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Retrospective Analysis ◽  
Malaria Control ◽  
Time Series Data ◽  
Southern Oscillation ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Series Data ◽  
Malaria Control Programme

Abstract Background: The present study provides a countrywide perspective of the malaria situation in Panama over a long-term framework, with the purpose of identifying historical malaria resurgence events and their potential causes. Methods: A descriptive-ecological study was conducted by analyzing demographic and epidemiological annual malaria time series data in Panamá (1884 – 2019) using several data sources. Malaria intensity indicators were calculated during the study period. We also analyze the effects of El Niño Southern Oscillation on malaria transmission using a retrospective analysis of malaria cases between 1957 and 2019. Results: Several factors were identified responsible for malaria resurgence in Panama, mostly related with Malaria Control Programme weakening. During the past 20 years (2000 – 2019) malaria has progressively increased its prevalence within indigenous settlements, with a predominance of male cases and a high proportion (15% of total cases) in children less than 5 years old. During this period a significant and increasing proportion of the P. falciparum total cases were imported. Our retrospective analysis (1957 - 2019) evidenced that ENSO has a significant impact on malaria transmission dynamics in Panama. Conclusions: Data analysis confirmed that although authorities have been successful in focalizing malaria transmission in the country, there are still neglected issues to be solved and important intercultural barriers that need to be addressed in order to achieve elimination of the disease by 2022. This information will be useful for targeting strategies by the National Malaria Control Programme.

scholarly journals Seeking research questions from implementers: considerations for leveraging ground actors research needs in the fight against malaria in West Africa

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Tete S. Amouh ◽  
Saidou Malam Ekoye ◽  
Césaire D. Ahanhanzo ◽  
Tinga Robert Guiguemdé ◽  
Issiaka Sombié
Keyword(s):  
Malaria Control ◽  
Neglected Tropical Diseases ◽  
National Malaria Control Programme ◽  
Monitoring And Evaluation ◽  
Control Programme ◽  
Malaria Control Programme ◽  
Programme Implementation ◽  
African Countries ◽  
Malaria Programme ◽  
Research Questions

Abstract Background To strengthen the fight against malaria, it is imperative to identify weaknesses and possible solutions in order to improve programmes implementation. This study reports experiences gained from collaboration between decision-makers and researchers from a World Bank project (Malaria and Neglected Tropical Diseases in the Sahel, SM/NTD). The objectives of this paper were to identify bottlenecks in malaria programme implementation as well as related research questions they bring up. Methods Questionnaire addressed to National Malaria Control Programme managers and prioritization workshops were used as a medium to identify research questions. The bottlenecks in malaria programme implementation were identified in seven thematic areas namely governance, human resources, drugs, service provision, use of prevention methods, monitoring and evaluation (M and E), and public support or buy-in. The first five priority questions were: (1) compliance with drug doses on the second and third days during the seasonal chemoprevention (SMC) campaigns, (2) the contribution of community-based distributors to the management of severe cases of malaria in children under 5 years, (3) the SMC efficacy, (4) artemisinin-based combination therapy (ACT) tolerance and efficacy according to existing guidelines, and (5) the quality of malaria control at all levels of the health system. Results and conclusion This work showed the effectiveness of collaboration between implementers, programmes managers, and researchers in identifying research questions. The responses to these identified research questions of this study may contribute to improving the implementation of malaria control programmes across African countries.

scholarly journals Multiple insecticide resistance target sites in adult field strains of An. gambiae (s.l.) from southeastern Senegal

2020 ◽  
Author(s):  
El hadji Diouf ◽  
El hadji Amadou Niang ◽  
Badara Samb ◽  
Cheikh Tidiane Diagne ◽  
Mbaye Diouf ◽  
...  
Keyword(s):  
Insecticide Resistance ◽  
Indoor Residual Spraying ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Molecular Techniques ◽  
Target Site ◽  
Malaria Control Programme ◽  
Insecticide Susceptibility ◽  
High Coverage ◽  
Pyrethroid Insecticides

Abstract Background: High coverage of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of vector control strategy in Senegal where insecticide resistance by the target vectors species is a great of concern. This study explore insecticide susceptibility profile and target-site mutations mechanisms within the Anopheles gambiae complex in southeastern Senegal. Methods: Anopheles larvae were collected from Kedougou and Wassadou/Badi, two sites from southeastern Senegal, in October and November 2014, and reared until adult emergence. Wild Fo Adults mosquitoes were morphologically identified to species. Susceptibility of 3-5-day old An. gambiae (s. l.) samples to eleven (11) insecticides belonging to the four insecticide classes was assessed using WHO insecticide susceptibility bioassays. Tested samples were identified using molecular techniques as well as detection of insecticide resistance target-site mutations (kdr, ace-1 and rdl).Results: A total of 3,742 An. gambiae (s.l.) were exposed to insecticides (2,439 from Kedougou and 1,303 from Wassadou-Badi). Tests with pyrethroid insecticides and DDT showed high level of resistance in both Kedougou and Wassadou/Badi. Pirimiphos-methyl and Malathion resistance were not detected while Bendoicarb and Fenitrothion resistance were confirmed in Kedougou. Of the 745 specimens of An. gambiae (s.l.) genotyped, An. gambiae (s.s.) (71.6%) was the predominant species, followed by An. arabiensis (21.7%), An. coluzzii (6.3%) and hybrids (An. gambiae (s.s.) /An. coluzzii; 0.4%). All target site mutations investigated (Vgsc-1014F; Vgsc-1014S, Ace-1 and Rdl) were found at different frequencies in the species of the Anopheles gambiae (s.l.). Vgsc-1014F mutation is more frequent in An. gambiae and An. coluzzii than An. arabiensis. Vgsc-1014S was present in An. gambiae (s.l.) populations in Wassadou but not in Kedougou. Ace-1 and rdl mutations were more frequent in An. gambiae (s.s.) in comparison to An. arabiensis and An. coluzzii. Conclusions: Resistance to all the four insecticide classes tested was detected in southeastern Senegal as well as all target site mutations investigated were found. Data will be used by the national Malaria Control Programme.

scholarly journals Evaluation of the effect of supervised anti-malarial treatment on recurrences of Plasmodium vivax malaria

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Kelry Mazurega Oliveira Dinelly ◽  
Sheila Vitor-Silva ◽  
Jose Diego Brito-Sousa ◽  
Vanderson Souza Sampaio ◽  
Milena Gabriela Oliveira Silva ◽  
...  
Keyword(s):  
Malaria Control ◽  
Vivax Malaria ◽  
Health Workers ◽  
Real Life ◽  
National Malaria Control Programme ◽  
Standard Of Care ◽  
Control Programme ◽  
Malaria Control Programme ◽  
The Real ◽  
Plasmodium Vivax Malaria

Abstract Background Relapses in vivax malaria have posed great challenges for malaria control, and they also account for a great proportion of reported cases. Knowing the real effectiveness of a 7-day primaquine (PQ) scheme is crucial in order to evaluate not only the cost-effectiveness of implementing new anti-hypnozoite drugs, but also how health education strategies can guarantee better compliance and be reinforced. This study aimed to evaluate the effect of daily treatment with chloroquine and PQ supervised by health workers versus prescription without supervision. Methods The outcome was the passive detection of new positive thick blood smears up to 180 days, based on the official data records from the National Malaria Control Programme. The recurrences seen in the real life were, therefore, used as a surrogate for true relapses. Results Patients under supervised treatment had a lower risk of recurrence up to day 180 when compared to the unsupervised treatment (17.9% vs. 36.1%; p = 0.027). Conclusions The lack of supervision in the non-supervised group (which followed standard of care in the real life) enabled proper comparison, as consent itself would have lead to greater compliance in this group. Future studies should scale such an analysis to different settings in the Brazilian Amazon.

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