scholarly journals Enumeration of Salivary Streptococci and Lactobacilli in Children with Differing Caries Experiences in a Rural Indian Population

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Sreeja Ravindran ◽  
Minal Chaudhary ◽  
Madhuri Gawande
Keyword(s):  
Dental Caries ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Mutans Streptococci ◽  
Plate Count ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Group Iii ◽  
Group I ◽  
Plate Count Method

Objectives. Compare the total salivary Streptococci and Lactobacilli counts in cleft and noncleft children with differing caries experiences, correlate the bacterial counts with dmft/DMFT status and identify the different biotypes of Mutans Streptococci (MS). Patients. Group I included thirty subjects with dental caries (DC) and cleft lip and palate (CL/P); Group II had thirty subjects with DC but without CL/P. Group III comprised a control of thirty subjects with neither DC nor CL/P. Methodology. Enumeration of total salivary Streptococci and Lactobacilli was done by the plate count method and correlation of counts with dmft/ DMFT status examined. Differences in biochemical reactions were used to identify the biotypes. Results. Streptococci colonies in CL/P children with caries (64.30 ± 24.52) was significantly higher than in children with no CL/P or caries (45.57 ± 16.73). No significant differences in the Lactobacilli count were observed. dmft/DMFT status and Streptococci counts showed a strong positive correlation whereas Lactobacilli counts showed a moderate correlation. S. mutans was the predominant biotype. Conclusions. Higher total salivary Streptococci and Lactobacilli counts exist in cleft subjects with caries than in the non-cleft subjects. Positive correlation between dmft/DMFT scores and salivary Streptococci reinforces its role in DC. S. mutans and S. sobrinus are the biotypes more frequently associated with dental caries in children.

Microbial Profile and Dental Caries in Cleft Lip and Palate Babies Between 0 and 3 Years Old

2018 ◽  
Vol 56 (3) ◽  
pp. 349-356 ◽  
Author(s):  
Müesser Ahu Durhan ◽  
Nursen Topcuoglu ◽  
Guven Kulekci ◽  
Ege Ozgentas ◽  
Ilknur Tanboga
Keyword(s):  
Dental Caries ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Basic Research ◽  
Pediatric Dentistry ◽  
Mutans Streptococci ◽  
Primary Tooth ◽  
Control Group ◽  
Initial Caries ◽  
Cleft Lip Palate

Objective: The aim of this study was to examine the microbiological changes in newborn babies with cleft lip palate from birth up to age 3 and to correlate them with their caries levels and mothers’ microbiological data and to compare with normal infants. Basic Research Design: Prospective. Settings: Marmara University, Faculty of Dentistry, Pediatric Dentistry Clinic, and Şişli Hamidiye Etfal Education and Research Hospital New Born Clinic. Patients/Participants: Cleft lip palate (n = 21) and healthy (n = 13) newborns and their mothers. Material and Methods: Intraoral samples were taken from babies in each group at least 3 times over the 3 years. Saliva samples of the mothers were collected just after the birth of the babies and examined microbiologically. Dental caries was noted as either present or absent. Results: The most frequent microorganisms were candida, found at birth (n = 9, 42%) in cleft palate with or without cleft lip (CP±L) group. The number of babies infected with Lactobacilli were found to be significantly higher in the CP±L group than in the control group at birth ( P = .029) and after eruption of the first primary tooth ( P = .030). Mutans Streptococci were found in 10% of babies with CP±L at birth. Initial caries was identified in 20% of the babies with an oral cleft compared with 0% of the controls after eruption of the first primary incisors. Conclusion: The results show that the CP±L babies must be considered as a group with an increased caries risk.

scholarly journals Study of serum Ceruloplasmin, Malondialdehyde (MDA) and hs-CRP as biomarkers of severity in Psoriasis

2021 ◽  
Vol 8 (3) ◽  
pp. 70-73
Author(s):  
Prashant K. ◽  
MI Khan
Keyword(s):  
General Medicine ◽  
Sampling Technique ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Serum Ceruloplasmin ◽  
Group Iii ◽  
Medical College ◽  
Group I ◽  
Group Ii ◽  
Hs Crp

Background : Psoriasis is one of the common diseases diagnosed in dermatology clinics. It is characterized by erythematous and sharply demarcated papules covered by silvery micaceous scales. Although, etiology is an unclear genetic predisposition seen in 50% of cases. This study aimed to determine the role of malondialdehyde (MDA), ceruloplasmin, and C-Reactive Protein (hs-CRP) as markers of severity of the disease. Methods: N= 75 patients were selected and divided into three categories of different severity based on PASI scores. Those with PASI score of < 10 were mild cases included in group I and with PASI Scores of 11-15 were moderate cases included in group II and PASI scores >15 were in group III. N=25 age and sex-matched taken from healthy people were included in group IV controls. Results: correlation coefficient (r) values were calculated between PASI and biomarkers. Of the biomarkers, a strong positive correlation was shown by serum ceruloplasmin levels in group I and group II (r = + 0.9). Ironically the values in group III of ceruloplasmin were positive the correlation was not strong. The Malondialdehyde values in group III also showed a strong positive correlation with r values of + 0.93. In the hsCRP group, a strong positive correlation was found in group III however, a weak positive correlation was found in group I and group II. Materials and Methods: A Hospital-based Prospective study was conducted in the Department of Medicine, Santhiram medical college & general hospital for a 2 year period.Universal Sampling Technique was used for the selection of study subjects.The study population included patients admitted with fever, flank pain, and positive urine or blood cultures in the department of general medicine in Santhiram medical college and general hospital.The final sample size was 50 subjects. Conclusion: Serum ceruloplasmin was positively correlated with PASI scores and serum MDA levels were highly correlated in severe cases of psoriasis. The hs-CRP was also found to be elevated in the psoriasis cases as compared to controls however, a significant positive correlation was found in severe cases. Therefore, psoriasis severity can be mo

scholarly journals Effects of sagittal maxillary growth hypoplasia severity on mandibular asymmetry in unilateral cleft lip and palate subjects

2011 ◽  
Vol 81 (5) ◽  
pp. 872-877 ◽  
Author(s):  
Ashok Kumar Jena ◽  
Satinder Pal Singh ◽  
Ashok Kumar Utreja
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Asymmetry Index ◽  
Group Iii ◽  
Gonial Angle ◽  
Mandibular Asymmetry ◽  
Perpendicular Distance ◽  
Group I ◽  
Maxillary Growth ◽  
Group Ii

Abstract Objective: To test the hypothesis that sagittal maxillary growth hypoplasia has no effect on mandibular asymmetry among subjects with complete unilateral cleft lip and palate (UCLP). Design: A total of 86 subjects (normal noncleft, 42; UCLP, 44) in the age range of 15 to 25 years were chosen. Normal noncleft subjects were included in Group I. Based on the severity of sagittal maxillary growth hypoplasia, subjects with UCLP were divided into two groups. Subjects with UCLP in whom the SNM angle was ≥71 degrees and the M-point to Nasion perpendicular distance was ≤−10 mm were included in Group II. Group III consisted of subjects with UCLP in whom the SNM angle was &lt;71 degrees and the M-point to Nasion perpendicular distance was &gt;−10 mm. The mandibular asymmetry index (condylar, ramal, and condylar+ramal), gonial angle, and depth of the antigonial notch of three groups of subjects were examined on orthopantomograms (OPGs). Results: Among Group II subjects in whom sagittal maxillary growth was near normal, ramal and condylar+ramal heights were significantly less on the cleft side than on the normal side (P &lt; .01). Condylar, ramal, and condylar+ramal asymmetry indices were significantly greater among Group II subjects. Mandibular asymmetry indices among Group III subjects were comparable with those in Group I subjects. Conclusion: The hypothesis was rejected. The mandible was significantly asymmetrical among subjects with UCLP in whom sagittal maxillary growth was near normal, whereas the mandible was nearly symmetrical among subjects with UCLP in whom sagittal maxillary growth hypoplasia was very severe.

Does Infant Orthopedics and Neonate Lip Surgery Influence the Occlusal Relationship in Patients With Unilateral Cleft Lip and Palate (UCLP)?

2021 ◽  
pp. 105566562098435
Author(s):  
Thalita V. Galassi ◽  
Telma V. Souza-Brosco ◽  
Lucy D. Lopes ◽  
Araci Malagodi de Almeida ◽  
Gisele da Silva Dalben ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Dental Arch ◽  
Surgical Timing ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Spearman Test ◽  
Infant Orthopedics

Objective: To compare occlusal relationship in patients undergoing neonate versus conventional lip surgery (LS) with and without infant orthopedics (IO) by assessment of dental arch relationship in individuals with complete unilateral cleft lip and palate. Material and Methods: Three groups treated by different protocols; Group I: neonate LS (1-15 days) + IO and palatoplasty (13-31 months); Group II: LS (3-12 months) + IO and palatoplasty (15-35 months); and Group III: LS (3-6 months) without IO and palatoplasty (12-18 months). The 112 intraoral photographs of individuals of all groups, obtained between 6 and 12 years of age, were assessed by the occlusal index for intraoral photograph rating. The groups were compared by the χ2 test. The correlation between surgical timing and the scores was tested by the Spearman test ( P < .05). Results: Group I presented the highest percentage of score 5, group II exhibited highest percentage of score 1, and group III presented the lowest percentage of score 5 according to the χ2 test ( P = .029). The Spearman correlation test revealed statistically significant difference between timing of LS and the occlusal index. The earlier the surgical timing, the higher the occlusal index ( P = .019). Conclusions: Infant orthopedics has demonstrated the possibility of postponing primary plastic surgeries. Patients submitted to late lip and palate repair had the best prognosis, while patients undergoing lip repair from 1 to 15 days of life, even operating the palate later, had the worst prognosis. Neonate LS negatively influenced the occlusal relationships.

Comparison of Dental Caries Prevalence in Patients with Cleft Lip and/or Palate and Their Sibling Controls

2009 ◽  
Vol 46 (5) ◽  
pp. 529-531 ◽  
Author(s):  
Mahmoud Al-Dajani
Keyword(s):  
Dental Caries ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Maxillofacial Surgery ◽  
Permanent Teeth ◽  
Control Group ◽  
Oral And Maxillofacial Surgery ◽  
Caries Prevalence ◽  
Dmft Index ◽  
And Control

Objective: To evaluate the prevalence of dental caries in patients with cleft lip and/or palate and their cleft-free sibling controls. Methods: The two subject groups (patient and control) comprised 106 participants. The former group consisted of 53 patients with cleft lip and/or palate, aged 12 to 29 years, who visited the Oral and Maxillofacial Surgery Hospital at Damascus University of Syria. The control group consisted of the patients’ siblings who had no clefts, and they were sex matched to the patient group. Dental caries were examined clinically and were reported using the decayed, missing, and filled permanent teeth (DMFT) index. The DMFT scores were compared between the two groups. Results: The author found an overall association of dental caries with the presence of cleft lip and/or palate (odds ratio  =  2.52; 95% confidence interval  =  1.389–4.574; p < .05). The DMFT index scores were proportionally higher in patients with cleft lip and/or palate compared with the control group (p < .001). Conclusion: Subjects with cleft lip and palate are susceptible to dental caries independently of socioeconomic status.

scholarly journals Microbiome signature and diversity regulates the level of energy production under anaerobic condition

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Shaminur Rahman ◽  
M. Nazmul Hoque ◽  
Joynob Akter Puspo ◽  
M. Rafiul Islam ◽  
Niloy Das ◽  
...  
Keyword(s):  
Indicator Species ◽  
Energy Production ◽  
Environmental Temperature ◽  
Group Iv ◽  
Methanosarcina Barkeri ◽  
Spearman Correlation ◽  
Positive Correlation ◽  
Group Iii ◽  
Group I ◽  
Group Ii

AbstractThe microbiome of the anaerobic digester (AD) regulates the level of energy production. To assess the microbiome diversity and composition in different stages of anaerobic digestion, we collected 16 samples from the AD of cow dung (CD) origin. The samples were categorized into four groups (Group-I, Group-II, Group-III and Group-IV) based on the level of energy production (CH4%), and sequenced through whole metagenome sequencing (WMS). Group-I (n = 2) belonged to initial time of energy production whereas Group-II (n = 5), Group-III (n = 5), and Group-IV (n = 4) had 21–34%, 47–58% and 71–74% of CH4, respectively. The physicochemical analysis revealed that level of energy production (CH4%) had significant positive correlation with digester pH (r = 0.92, p < 0.001), O2 level (%) (r = 0.54, p < 0.05), and environmental temperature (°C) (r = 0.57, p < 0.05). The WMS data mapped to 2800 distinct bacterial, archaeal and viral genomes through PathoScope (PS) and MG-RAST (MR) analyses. We detected 768, 1421, 1819 and 1774 bacterial strains in Group-I, Group-II, Group-III and Group-IV, respectively through PS analysis which were represented by Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria, Spirochaetes and Fibrobacteres phyla (> 93.0% of the total abundances). Simultaneously, 343 archaeal strains were detected, of which 95.90% strains shared across four metagenomes. We identified 43 dominant species including 31 bacterial and 12 archaeal species in AD microbiomes, of which only archaea showed positive correlation with digester pH, CH4 concentration, pressure and temperature (Spearman correlation; r > 0.6, p < 0.01). The indicator species analysis showed that the species Methanosarcina vacuolate, Dehalococcoides mccartyi, Methanosarcina sp. Kolksee and Methanosarcina barkeri were highly specific for energy production. The correlation network analysis showed that different strains of Euryarcheota and Firmicutes phyla exhibited significant correlation (p = 0.021, Kruskal–Wallis test; with a cutoff of 1.0) with the highest level (74.1%) of energy production (Group-IV). In addition, top CH4 producing microbiomes showed increased genomic functional activities related to one carbon and biotin metabolism, oxidative stress, proteolytic pathways, membrane-type-1-matrix-metalloproteinase (MT1-MMP) pericellular network, acetyl-CoA production, motility and chemotaxis. Importantly, the physicochemical properties of the AD including pH, CH4 concentration (%), pressure, temperature and environmental temperature were found to be positively correlated with these genomic functional potentials and distribution of ARGs and metal resistance pathways (Spearman correlation; r > 0.5, p < 0.01). This study reveals distinct changes in composition and diversity of the AD microbiomes including different indicator species, and their genomic features that are highly specific for energy production.

scholarly journals Levels of some trace metals and related enzymes in workers at storage-battery factories in Iraq

2000 ◽  
Vol 6 (1) ◽  
pp. 76-82 ◽  
Author(s):  
J. K. Mehdi ◽  
F. J. M. Al Imarah ◽  
A. A. Al Suhail
Keyword(s):  
Trace Metals ◽  
Private Sector ◽  
Significant Positive Correlation ◽  
Storage Battery ◽  
Positive Correlation ◽  
Group Iii ◽  
Group I ◽  
Lead And Zinc ◽  
Lead Levels ◽  
Aminolevulinate Dehydratase

Levels of some trace metals [copper, iron, lead and zinc], aminolevulinate dehydratase [ALAD], caeruloplasmin and haemoglobin were measured in the blood of 37 male workers from private-sector storage-battery factories. The men were divided into three groups depending on their jobs: 11 chargers [group I], 8 repair workers [group II]and 18 casting workers [group III]; 60 men were selected as controls. Mean levels were 14.63, 36.35, 58.00 and 71.70 mg/100 mL for lead, 192.54, 133.90, 96.75 and 45.37 U/mL for ALAD, and 14.02, 12.72, 12.20 and 11.40 g/100 mL for haemoglobin for control and groups I, II and III respectively. Significant negative correlations were found between lead and both ALAD and haemoglobin. The only significant positive correlation was between lead levels and duration of exposure

scholarly journals Bone-anchored maxillary protraction in patients with unilateral cleft lip and palate:

2020 ◽  
Vol 90 (4) ◽  
pp. 539-547 ◽  
Author(s):  
Eman H. Elabbassy ◽  
Noha E. Sabet ◽  
Islam T. Hassan ◽  
Dina H. Elghoul ◽  
Marwa A. Elkassaby
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Three Dimensions ◽  
Class Iii ◽  
Maxillary Expansion ◽  
Forward Movement ◽  
Maxillary Protraction ◽  
Computed Tomography Images ◽  
Group I ◽  
Effective Treatment Modality

ABSTRACT Objectives To assess the effectiveness of bone-anchored maxillary protraction (BAMP) in patients with unilateral cleft lip and palate (UCLP) and whether it was enhanced when preceded by maxillary expansion. Materials and Methods The sample consisted of 28 growing children (9–13 years old) with UCLP and Class III malocclusion. They were divided into two equal groups. In group I, patients were treated with BAMP not preceded by maxillary expansion. In group II, patients were treated with BAMP preceded by maxillary expansion. To assess treatment changes in three dimensions, Cone-beam computed tomography images were taken 1 week after surgical placement of the miniplates (T1) and after 9 months of treatment (T2). Results BAMP produced forward movement of the maxilla in both groups (3.17 mm) and (3.37 mm) respectively, without significant differences between the two groups except for clockwise rotation of the palatal plane in group I (1.60). Conclusions BAMP is an effective treatment modality for correcting midface deficiency in patients with UCLP whether or not maxillary expansion was carried out.

Conversational Skills of Children with Cleft Lip and Palate: A Replication and Extension

2006 ◽  
Vol 43 (2) ◽  
pp. 179-188 ◽  
Author(s):  
Melissa S. Frederickson ◽  
Kathy L. Chapman ◽  
Mary Hardin-Jones
Keyword(s):  
Speech Production ◽  
Cleft Lip ◽  
Significant Positive Correlation ◽  
Cleft Lip And Palate ◽  
Individual Child ◽  
Language Performance ◽  
Positive Correlation ◽  
Conversational Skills ◽  
Conversational Interactions ◽  
The Relationship

Objective To replicate and to extend a previous study examining the conversational skills of children with cleft lip and palate. Participants Thirty-four children (33 to 44 months) participated: 17 children with cleft lip and palate and 17 noncleft children. Methods The children were observed during an interaction with caregivers in their homes. Samples of caregiver-child interactions were coded as assertive or responsive, for type of conversational act, and for discourse level categories. Profiles of conversational activity were determined for each child based on the coding. Correlations were performed to examine the relationship between assertiveness and speech variables (articulation and resonance) for the children with cleft lip and palate. Results Group comparisons revealed that the children with cleft lip and palate produced fewer assertive utterances, were less likely to respond adequately to comments by caregivers, and produced more topic maintaining and fewer topic extending utterances than did their noncleft peers during conversational interactions. Examination of individual child data indicated that 35% of the children with cleft lip and palate exhibited conversational profiles characterized by either low assertiveness or low responsiveness. Finally, a significant positive correlation was noted between conversational assertiveness and speech production skills. Conclusion These findings suggested that the children with cleft lip and palate were less conversationally assertive than their noncleft peers. Further, there appeared to be a relationship between speech production skills and conversational skills, suggesting that poor speech may be impacting language performance for these children.

scholarly journals The influence of mouthrinses with antimicrobial solutions on the inhibition of dental plaque and on the levels of mutans streptococci in children

2002 ◽  
Vol 16 (2) ◽  
pp. 101-106 ◽  
Author(s):  
Nildiceli Leite Melo Zanela ◽  
Maria Francisca Thereza Borro Bijella ◽  
Odila Pereira da Silva Rosa
Keyword(s):  
Sodium Fluoride ◽  
Dental Plaque ◽  
Daily Basis ◽  
Group Iv ◽  
Chlorhexidine Gluconate ◽  
Plaque Formation ◽  
Mutans Streptococci ◽  
Group Iii ◽  
Group I ◽  
Group Ii

The effect of daily mouthrinses on dental plaque accumulation and on salivary mutans streptococci was investigated in 200 children. The utilized solutions were: a placebo solution composed of mentholated deionized water (group I); 0.12% chlorhexidine gluconate associated to 0.05% sodium fluoride (group II); 0.2% chlorhexidine digluconate (group III), and 0.5% stevioside mixed with 0.05% sodium fluoride, with pH 3.4 (group IV). In order to verify the effect on plaque formation, the accumulation of plaque was assessed by means of the Löe12 index, at the beginning and at the end of the experiment, whereas the quantification of cariogenic streptococci was accomplished on three saliva samples collected at 3 different moments: before the first mouthrinse, 24 hours after the first mouthrinse and 1 week after the last mouthrinse. The mouthrinsing routine was carried out on a daily basis during 4 weeks. Five milliliters of solution were rinsed during 1 minute. The results revealed 4.10, 26.75, 41.20, and 5.91% of reduction in plaque accumulation for groups I, II, III, and IV, respectively. Comparisons between the groups as to plaque reduction revealed that groups II and III were significantly different from groups I (control) and IV (p < 0.05), but did not differ from each other. The solution utilized by group III was the least accepted by children and, as the solution utilized by group II, caused mild dental pigmentation. There were no statistically significant differences as to the levels of mutans streptococci, probably due to the low initial levels observed in each one of the four groups.

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