scholarly journals Intrasellar Chondroid Chordoma: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Renata M. Hirosawa ◽  
Antonio B. A. Santos ◽  
Mariana M. França ◽  
Viciany Erique Fabris ◽  
Ana Valéria B. Castro ◽  
...  
Keyword(s):  
Case Report ◽  
Pituitary Adenomas ◽  
Bone Tumors ◽  
Bone Erosion ◽  
Sellar Region ◽  
Malignant Bone Tumors ◽  
Intracranial Neoplasms ◽  
Progressive Loss ◽  
Chondroid Chordoma ◽  
History Of

Chordomas are tumors derived from cells that are remnants of the notochord, particularly from its proximal and distal extremes, they are mainly midline and represent approximately 1% of all malignant bone tumors and 0.1 to 0.2% of intracranial neoplasms. Chordomas involving the sellar region are rare. Herein, we describe a 57-year-old male patient presenting with a history of retro-orbital headache, progressive loss of vision, and clinical features of hypopituitarism, for over 2 months. During evaluation, the CT scan revealed a large contrast-enhancing intrasellar tumor with a 3.6-cm largest diameter. The patient underwent transsphenoidal partial resection of the tumor, and histological examination was consistent with the diagnosis of chondroid chordoma. Although chordomas are rare, they may be considered to constitute a differential diagnostic of pituitary adenomas, especially if a calcified intrasellar tumor with bone erosion is diagnosed.

INTRAOSSEOUS XANTHOMA OF THE DISTAL RADIUS — A CASE REPORT

Hand Surgery ◽  
2014 ◽  
Vol 19 (02) ◽  
pp. 223-226 ◽  
Author(s):  
Kannan Karuppiah Kumar ◽  
Yorell Manon-Matos ◽  
Sunil Thirkannad
Keyword(s):  
Case Report ◽  
Distal Radius ◽  
Bone Tumors ◽  
Rare Condition ◽  
Malignant Bone Tumors ◽  
History Of

An intraosseous xanthoma is a very rare condition. It has an aggressive appearance on radiographs mimicking primary or metastatic malignant bone tumors. We report a case of intraosseous xanthoma of the distal radius in a 51-year-old male with no history of hyperlipidaemia. To the best of our knowledge, this condition has not been reported so far in the wrist and forearm region. The lesion was successfully excised and at last follow-up, there were no signs of recurrence and patient has been symptom-free.

scholarly journals Genetic Testing Distinguishes Multiple Chondroid Chordomas with Neuraxial Bone Metastases from Multicentric Tumors

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Hiroshi Kobayashi ◽  
Masahiro Shin ◽  
Naohiro Makise ◽  
Aya Shinozaki-Ushiku ◽  
Masachika Ikegami ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Growth Factor Receptor ◽  
Malignant Bone Tumors ◽  
Case Presentation ◽  
Systemic Dissemination ◽  
Initial Surgery ◽  
Chondroid Chordoma ◽  
Multiple Metastases ◽  
Epidermal Growth ◽  
Generation Sequencing

Background. Chordomas are rare malignant bone tumors preferentially forming in neuraxial bones. Chondroid chordoma is a subtype of chordoma. Chordomas reportedly present as synchronous multiple lesions upon initial diagnosis. However, it remains unknown whether these lesions are multicentric or metastatic multiple chordoma tumors. Case Presentation. Here, we present the case of a 57-year-old woman with multiple chordomas at the clivus, C6, and T12 upon initial presentation. Sequential surgeries and radiotherapy were performed for these lesions, and postoperative histological diagnosis revealed that all lesions were chondroid chordomas. Next-generation sequencing revealed that these lesions harbored a common somatic mutation in epidermal growth factor receptor (EGFR), c.3617A>C, which is not considered a pathogenic chordoma mutation, thus indicating that these lesions were not multicentric but rather multiple metastatic tumors. Subsequent multiple metastases to the lung and appendicular and axial bones were detected 15 months after the initial surgery. Recurrent lesions at the clivus progressed despite EGFR-targeted therapy, surgery, and radiotherapy. Conclusion. The present evidence indicates that multiple chordomas in this case were caused by multiple metastases rather than multicentric lesions. Multiple presentations of chordoma imply systemic dissemination of tumor cells, and novel efficient systemic therapy is required to treat this disease.

scholarly journals Salivary Gland-Like Tumor of the Sella

2007 ◽  
Vol 34 (4) ◽  
pp. 478-482 ◽  
Author(s):  
Wouter van Furth ◽  
Harley S. Smyth ◽  
Eva Horvath ◽  
Kalman Kovacs ◽  
Fateme Salehi ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pituitary Adenomas ◽  
Biological Behavior ◽  
Benign Tumors ◽  
Sellar Region ◽  
Non Invasive ◽  
Medical Issues ◽  
Sellar Tumor ◽  
Pituitary Carcinomas

Tumors arising in the sellar region are predominantly benign, non-invasive pituitary adenomas. Invasive pituitary adenomas (approximately 35 % of the pituitary adenomas) and pituitary carcinomas (0.1 – 0.5 %) arise from the same cells in the pituitary gland as the benign tumors, but have different pathology and biological behavior. A wide variety of nonadenomatous lesions involve the sellar region. These include tumors that arise specifically from sellar and suprasellar structures, as well as those that are also found elsewhere in the CNS (e.g. meningioma, glioma, metastasis, etc.). Typical nonadenomatous tumors that originate in the sellar region are craniopharyngioma and Rathke’s cleft cyst. The purpose of this paper is to describe another nonadenomatous tumor specific to the sellar region, a salivary gland-like tumor, and review the literature on this subject. This case report will also illustrate the management decisions regarding a patient with multiple medical issues and an aggressive sellar tumor.

scholarly journals Large desmoplastic fibroma: case report using microvascularized fibula graft for reconstruction

2014 ◽  
Vol 17 (1) ◽  
pp. 81
Author(s):  
Cleverson Patussi ◽  
Laurindo Moacir Sassi ◽  
Regiane Benez Bixofis ◽  
Paola Andrea Galbiatti Pedruzzi ◽  
Alfredo Benjamim Duarte Da Silva ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Bone Tumors ◽  
Rare Tumor ◽  
Desmoplastic Fibroma ◽  
Fibula Graft ◽  
Floor Of The Mouth ◽  
Mandibular Body ◽  
History Of ◽  
Expansive Lesion

<p><span lang="EN-US">The Desmoplastic Fibroma is a benign rare tumor of fibroblastic origin, representing only 0.03% of benign bone tumors. Displays aggressive behavior and high rates of recurrence, which makes the treatment more aggressive. We report a case of a 11 years-old female, complaining of increased volume in the jaw. The patient had an extensive swelling of the left mandibular body with invasion of the border of the tongue and floor of the mouth at the same side. She had a history of 4 recurrences at the same place. Images exams revealed expansive lesion in body and ramus of the jaw with involvement of soft tissue on the lingual side of the lesion. The treatment was excision of the lesion with extra oral access and reconstruction with microvascularized fibula graft. The patient lies in clinically and radiographic followed for 2 years without recurrence.</span></p>

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Scintigraphy with 99m Tc-Phosphonate and 67Gallium in Patients Suspected of Primary Bone Tumors

1982 ◽  
Vol 21 (04) ◽  
pp. 136-139 ◽  
Author(s):  
C.-J. Edeling
Keyword(s):  
Soft Tissue ◽  
Bone Scintigraphy ◽  
Primary Tumor ◽  
Bone Tumors ◽  
Whole Body ◽  
Skeletal Metastases ◽  
Malignant Bone Tumors ◽  
67Ga Scintigraphy ◽  
Primary Bone Tumors ◽  
Primary Bone

Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the primary tumor in 43 cases, skeletal metastases in 6 cases and soft-tissue metastases in 8 cases. In 25 patients with secondary malignant bone tumors, bone scintigraphy visualized a single lesion in 10 cases and several lesions in 15 cases, and 67Ga scintigraphy detected the primary tumor in 17 cases, skeletal metastases in 17 cases and soft-tissue metastases in 9 cases. In 21 patients with benign bone disease positive uptake of 99mTc-phosphonate was recognized in 19 cases and uptake of 67Ga in 17 cases. It is concluded that bone scintigraphy should be used in patients suspected of primary bone tumors. If malignancy is suspected, 67Ga scintigraphy should be performed in addition.

MR-Derived CT-Like Images and Simulated Radiographs versus Conventional Radiography in Patients with Benign and Malignant Bone Tumors

2018 ◽  
Author(s):  
Alexandra Gersing ◽  
Daniela Muenzel ◽  
Felix Kopp ◽  
Benedikt Schwaiger ◽  
Carolin Knebel ◽  
...  
Keyword(s):  
Bone Tumors ◽  
Conventional Radiography ◽  
Malignant Bone Tumors

An unusual presentation of epigastric pain due to thrombophlebitis of a recanalised umbilical vein – case report

2019 ◽  
Vol 98 (8) ◽  
pp. 326-327 ◽  
Keyword(s):  
Liver Cirrhosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Portal Hypertension ◽  
Liver Disease ◽  
Epigastric Pain ◽  
Umbilical Vein ◽  
History Of ◽  
Clinically Significant ◽  
Inflammatory Changes

Introduction: The umbilical vein can become recanalised due to portal hypertension in patients with liver cirrhosis but the condition is rarely clinically significant. Although bleeding from this enlarged vein is a known complication, the finding of thrombophlebitis has not been previously described. Case report: We report the case of a 62-year-old male with a history of liver cirrhosis due to alcoholic liver disease presenting to hospital with epigastric pain. A CT scan of the patient’s abdomen revealed a thrombus with surrounding inflammatory changes in a recanalised umbilical vein. The patient was managed conservatively and was discharged home the following day. Conclusion: Thrombophlebitis of a recanalised umbilical vein is a rare cause of abdominal pain in patients with liver cirrhosis.

Abnormal P wave Morphology in the Electrocardiogram of a Hurdle Runner with a History of Presyncope - A Case Report

2008 ◽  
Vol 12 (2) ◽  
pp. 46-48 ◽  
Author(s):  
Małgorzata Poręba ◽  
Robert Skalik ◽  
Rafał Poręba ◽  
Paweł Gać ◽  
Witold Pilecki ◽  
...  
Keyword(s):  
Case Report ◽  
P Wave ◽  
Wave Morphology ◽  
History Of
Sign in / Sign up

Export Citation Format

Share Document