Can a Short Intensive Course Affect Entrepreneurial Ability, Knowledge and Intent, or Further Entrepreneurial Study?

2015 ◽  
Vol 29 (5) ◽  
pp. 397-404 ◽  
Author(s):  
Jon Cornwall ◽  
Jodyanne Kirkwood ◽  
Gavin J. Clark ◽  
Stephen Silvey ◽  
Ruth D. Appleby ◽  
...  
Keyword(s):  
Small Group ◽  
Boot Camp ◽  
Business Development ◽  
Formal Study ◽  
Entrepreneurial Ability ◽  
Entrepreneurial Development ◽  
Before And After ◽  
Business Course ◽  
Almost All ◽  
Intensive Course

The SEED (Student Enterprise Experience in Dunedin) programme was developed as a four-week, intensive entrepreneurial ‘boot camp’ to provide a small group of participants with a highly experiential business course. Using pre-course and post-course surveys, the authors measured the entrepreneurial ability, knowledge and intentions of the sixteen SEED participants to determine whether the programme was successful as an educational format. The results showed that perceived entrepreneurial ability and knowledge significantly improved, while intent increased but not significantly. Almost all participants intended to start a business both before and after the course, while twice as many (six) indicated that they would undertake further formal study in entrepreneurship after the course compared to before. The data suggest that SEED is filling a niche in entrepreneurial development and support for budding entrepreneurs, with the course also facilitating local business development.

scholarly journals Effect of Integrated Neuromuscular Exercise in Physical Education Class on Health-Related Fitness in Female Children

Healthcare ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 312
Author(s):  
Marijana Sinđić ◽  
Draženka Mačak ◽  
Nikola Todorović ◽  
Bianka Purda ◽  
Maja Batez
Keyword(s):  
Physical Education ◽  
Muscular Fitness ◽  
Female Children ◽  
Before And After ◽  
Health Related ◽  
The Republic ◽  
Almost All ◽  
And Control ◽  
Cardiorespiratory Endurance ◽  
Health Related Fitness

Integrated neuromuscular training (INT) showed benefits for improving fundamental movement skills (FMS). However, the INT health-related fitness (HRF) effects are lacking. The current study aimed to determine the effects of INT implemented during physical education (PE) in a primary school in the Republic of Serbia on HRF in female children. The sample consisted of 72 healthy girls who were divided into the intervention (EG: n = 37; mean ± SD: age = 8.17 ± 0.31) and control (CG: n = 35; age = 8.11 ± 0.31) groups. The EG and CG performed the INT program and traditional PE activities two times per week within the first ~15 min of PE class, respectively. The Fitnessgram battery tests assessed the HRF (body composition, cardiorespiratory endurance, muscular fitness, and flexibility) before and after the program. After eight weeks, the EG significantly reduced all fat measures, while the CG decreased only triceps skinfold but to a smaller extent (F = 5.92, p < 0.02, ŋ2 = 0.09). Both groups significantly improved the performance of almost all muscular fitness tests (curl-ups, trunk lift, push-ups); however, the EG increased the push-ups more than the CG (F = 9.01, p < 0.01, ŋ2 = 0.14). The EG additionally improved the modified pull-ups (F = 14.09, p < 0.01, ŋ2 = 0.19) and flexed arm hang (F = 28.82, p < 0.01, ŋ2 = 0.33) tests. The flexibility and cardiorespiratory endurance of both groups did not significantly change after eight weeks. This approach of exercise showed positive acceptance and relatively good results after only eight weeks.

scholarly journals The Demerger Impact upon Sustainable Development of Economic Entities: Evidence from Romania

2021 ◽  
Vol 13 (15) ◽  
pp. 8316
Author(s):  
Camelia Mirela Baba ◽  
Constantin Duguleană ◽  
Marius Sorin Dincă ◽  
Liliana Duguleană ◽  
Gheorghița Dincă
Keyword(s):  
Sustainable Development ◽  
Business Strategies ◽  
The Sustainable Development ◽  
Ex Post ◽  
Before And After ◽  
Almost All ◽  
The Impact ◽  
Profitability Ratios ◽  
Positive Effect

The Covid-19 induced economic crisis has significantly affected almost all businesses from nearly every sector, causing severe financial problems, lack of cash assets, and decrease of revenues. In this context, the economic entities were forced to look for adjustment and rescue solutions of their activities. One possible solution for the recovery and reorganization of economic entities’ activities is demerger. This paper evaluates the impact of demerger upon the sustainable development of economic entities in terms of economic efficiency and financial performances. To achieve this goal, a statistical analysis of profitability ratios before and after the demerger, as well as a structural analysis of 268 demerger projects for the April 2012–April 2021 period, were performed. The results attest there are no significant differences between the ex-ante and ex-post financial performances. However, demerger seems to have a positive effect upon analyzed companies helping them to overcome economic hardships, rethink their business strategies, and continue their activity in the medium and long-term time horizon.

Discontinuation of Medication Overuse in Headache Patients: Recovery of Therapeutic Responsiveness

Cephalalgia ◽  
2006 ◽  
Vol 26 (10) ◽  
pp. 1192-1198 ◽  
Author(s):  
P Zeeberg ◽  
J Olesen ◽  
R Jensen
Keyword(s):  
Drug Withdrawal ◽  
Medication Overuse ◽  
Medication Overuse Headache ◽  
Headache Frequency ◽  
Female Ratio ◽  
Headache Centre ◽  
Before And After ◽  
Male Female Ratio ◽  
Few Data ◽  
Almost All

It is generally accepted that ongoing medication overuse nullifies the effect of prophylactic treatment, although few data support this contention. We set out to describe the treatment outcome in patients withdrawn from medication overuse and relate any improvement to a renewed effect of prophylaxis. For patients with probable medication-overuse headache (pMOH), treated and dismissed from the Danish Headache Centre in 2002 and 2003, we assed, from prospective headache diaries, the headache frequency before and after withdrawal of offending drugs and compared these frequencies with the headache frequency at dismissal. Among 1326 patients, 337 had pMOH. Eligible were 175, mean age 49 years, male/female ratio 1: 2.7. Overall, there was a 46% decrease in headache frequency from the first visit to dismissal ( P < 0.0001). Patients with no improvement 2 months after complete drug withdrawal ( N = 88) subsequently responded to pharmacological and/or non-pharmacological prophylaxis with a 26% decrease in headache frequency as measured from the end of withdrawal to dismissal ( P < 0.0001). At dismissal, 47% were on prophylaxis. Former non-responders to medical prophylaxis had a 49% decrease in headache frequency from first visit to dismissal ( P < 0.0001), whereas those who had never received prophylaxis had a 56% reduction ( P < 0.0001). This difference was not statistically significant ( P = 0.22). Almost all MOH patients benefit from drug withdrawal, either just from the withdrawal or by transformation from therapeutic non-responsiveness to responsiveness. According to the International Classification of Headache Disorders, 2nd edn, the MOH diagnosis requires improvement after drug withdrawal. Our data suggest that these diagnostic criteria are too strict.

scholarly journals Gender based EEG before and after acute bout of aerobic exercise

2014 ◽  
Vol 6 (2) ◽  
pp. 29-34
Author(s):  
Nirmala Limbu ◽  
Ramanjan Sinha ◽  
Meenakshi Sinha ◽  
Bishnu Hari Paudel
Keyword(s):  
Acute Exercise ◽  
Healthy Adult ◽  
Alpha Power ◽  
Medical Sciences ◽  
Acute Bout ◽  
Before And After ◽  
Eeg Changes ◽  
Gender Based ◽  
Exercise Induced ◽  
Almost All

Objective: We aimed to investigate how EEG frequency bands change in females in response to acute exercise compared to males.Methods: Consenting healthy adult females (n=15) & males (n=15) bicycled an ergometer at 50% HRmax for 20 min. EEG was recorded using 10-20 system from mid-frontal (F4 & F3), central (C4 & C3), parietal (P4 & P3), temporal (T4 & T3) & occipital (O2 & O1) regions. Exercise-induced EEG changes were compared between two sexes by Mann Whitney test. EEG power (μV2) is presented as median & interquartile range.Results: In females, as compared to males, resting right side delta, alpha, and beta activities were more in almost all recorded sites [delta: F4= 49.82 (44.23-63.56) vs. 35.5 (32.70-44.44), p < 0.001; etc], [alpha F4: 127.62 (112.89-149.03) vs. 49.36 (46.37-52.98), p < 0.001; etc], [beta F4= 18.96 (15.83-25.38)  vs. 14.77 (10.34-17.55), p < 0.05; C4= 21.16 (18.4-25.9) vs. 15.48 (9.66-19.40), p < 0.01; etc]. Similarly, females resting right theta activity was more in parietal [P4= 33.04 (25.1-42.41) vs. 22.3 (18.36-34.33), p < 0.05] & occipital [O2= 50.81 (30.64-66.8) vs. 26.85 (22.18-34.42), p < 0.001] regions than in males. They had similar picture on the left side also. The delta values of right alpha power was less in female in frontal [F4= -11.61 (-45.24 -3.64) vs. 9.48 (1.05-16.58), p < 0.01] and central [C4= -72 (-32.98-9.48) vs. 22.69 (13.03-33.05), p < 0.01] regions compared to males. Also, they had less delta values of left central alpha [C3= -8.32 (-32.65-6.1) vs. 16.5 (0.36-36.36), p < 0.01] and temporal beta [T3= -6.29 (-10.09- -1.49) vs. 1.24 (-0.84- 2.8), p < 0.001] power compared to males.Conclusion: At rest females may have high EEG powers in different bands. In response to acute exercise, they respond in reverse way as compared to males.DOI: http://dx.doi.org/10.3126/ajms.v6i2.11116Asian Journal of Medical Sciences Vol.6(2) 2015 30-35

scholarly journals SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Yukai Jing ◽  
Li Luo ◽  
Ying Chen ◽  
Lisa S. Westerberg ◽  
Peng Zhou ◽  
...  
Keyword(s):  
B Cells ◽  
B Cell ◽  
Immune Regulation ◽  
Cell Metabolism ◽  
Healthy Controls ◽  
Bcr Signaling ◽  
Before And After ◽  
B Cell Subsets ◽  
Almost All ◽  
Cd19 Expression

AbstractThe SARS-CoV-2 infection causes severe immune disruption. However, it is unclear if disrupted immune regulation still exists and pertains in recovered COVID-19 patients. In our study, we have characterized the immune phenotype of B cells from 15 recovered COVID-19 patients, and found that healthy controls and recovered patients had similar B-cell populations before and after BCR stimulation, but the frequencies of PBC in patients were significantly increased when compared to healthy controls before stimulation. However, the percentage of unswitched memory B cells was decreased in recovered patients but not changed in healthy controls upon BCR stimulation. Interestingly, we found that CD19 expression was significantly reduced in almost all the B-cell subsets in recovered patients. Moreover, the BCR signaling and early B-cell response were disrupted upon BCR stimulation. Mechanistically, we found that the reduced CD19 expression was caused by the dysregulation of cell metabolism. In conclusion, we found that SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism, which may provide a new intervention target to cure COVID-19.

scholarly journals The Use of Genotoxicity Endpoints as Biomarkers of Low Dose Radiation Exposure in Interventional Cardiology

2021 ◽  
Vol 9 ◽  
Author(s):  
Martha Habibi ◽  
Panagiotis K. Karyofyllis ◽  
Aggeliki Nikolakopoulou ◽  
Panagiotis Papagiannis ◽  
Pantelis Karaiskos ◽  
...  
Keyword(s):  
Risk Estimation ◽  
Biological Effects ◽  
Interventional Cardiology ◽  
Mean Values ◽  
Individual Level ◽  
Cardiac Procedures ◽  
Before And After ◽  
Radiation Induced ◽  
The Individual ◽  
Almost All

The effect of the reportedly low ionizing radiation doses, such as those very often delivered to patients in interventional cardiology, remains ambiguous. As interventional cardiac procedures may have a significant impact on total collective effective dose, there are radiation protection concerns for patients and physicians regarding potential late health effects. Given that very low doses (&lt;100 mSv) are expected to be delivered during these procedures, the purpose of this study was to assess the potency and suitability of current genotoxicity biomarkers to detect and quantitate biological effects essential for risk estimation in interventional cardiology. Specifically, the biomarkers γ-H2AX foci, dicentric chromosomes, and micronuclei, which underpin radiation-induced DNA damage, were studied in blood lymphocytes of 25 adult patients before and after interventional cardiac procedures. Even though the mean values of all patients as a group for all three endpoints tested show increased yields relative to baseline following medical exposure, our results demonstrate that only the γ-H2AX biomarker enables detection of statistically significant differences at the individual level (p &lt; 0.001) for almost all patients (91%). Furthermore, 24 h after exposure, residual γ-H2AX foci were still detectable in irradiated lymphocytes. Their decline was found to vary significantly among the individuals and the repair kinetics of γ-H2AX foci was found to range from 25 to 95.6% of their maximum values obtained.

scholarly journals Suitability of Macrophytes for Wastewater Treatment and Biogas Generation

2019 ◽  
Vol 9 (2S2) ◽  
pp. 16-18
Keyword(s):  
Wastewater Treatment ◽  
Water Hyacinth ◽  
Aquatic Macrophytes ◽  
Aquatic Macrophyte ◽  
Biogas Production ◽  
Oxygen Demand ◽  
Cow Dung ◽  
Water Lettuce ◽  
Before And After ◽  
Almost All

In this paper three sustainable approaches are made in waste management option. Firstly primary treated domestic sewage is treated by aquatic macrophytes using duckweed, water hyacinth and water lettuce. Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Total Suspended Solids (TSS), Total Dissolved Solids (TDS), Phosphate, Nitrates are tested before and after. Result indicates in terms of water quality, almost all three plants shows same removal efficiencies. BOD and TSS removal efficiency is attained more than 95%. COD and TDS removal is reached upto 50% for almost all plants. Secondly the used aquatic macrophytes for wastewater treatment is again used for generation of biogas (water lettuce unit, duckweed unit, water lettuce unit). In addition to three aquatic macrophytes, sludge is collected from aquatic macrophyte unit for generation of biogas. Comparison is made with conventional cow dung biogas unit. Result indicates water lettuce and duckweed produce biogas at earlier stage itself and water hyacinth takes some time for starting of biogas production. This may be due to the structure and texture causes some time for decomposition. Sludge gives maximum biogas generation among all experimental setup. Also in this study cow dung did not give biogas more may be due to poor blend ratio of cow dung with water is one of the reason.

scholarly journals Tumor immune microenvironment in non-small cell lung cancer with EGFR mutation before and after EGFR-TKIs treatment

2021 ◽  
Author(s):  
chao wang ◽  
lihui liu ◽  
sini li ◽  
hua bai ◽  
jie wang
Keyword(s):  
Lung Cancer ◽  
Kinase Inhibitors ◽  
Treatment Time ◽  
Acquired Resistance ◽  
Growth Factor Receptor ◽  
Immune Microenvironment ◽  
Tumor Immune Microenvironment ◽  
Before And After ◽  
Almost All ◽  
Egfr Tkis

Lung cancer is the most common cancer and a leading cause of death from cancer in men and women in the world. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are considered as the first-line treatment of EGFR mutated NSCLC. However, almost all patients eventually develop acquired resistance to EGFR-TKIs, with a median PFS of 9-14 months. With the development of immunotherapy, people realize that the interaction between tumor immune microenvironment (TIME) and tumor cells can also affect EGFR-TKIs treatment. TIME contains a variety of elements and previous researches of TIME in EGFR-TKIs therapy on NSCLC are decentralized. Here, we review the characteristics of TIME in NSCLC from EGFR-TKIs therapy and its role in TKIs resistance.

scholarly journals Strategi Kepala Sekolah Mengembangkan Budaya Islami Di SMP Islam Terpadu Se Kecamatan Tanayan Raya Pekanbaru

2020 ◽  
Vol 17 (1) ◽  
pp. 75-86
Author(s):  
Tika Emilda
Keyword(s):  
School Principals ◽  
Islamic Culture ◽  
Islamic Schools ◽  
Before And After ◽  
Almost All

This journal aims to find out the strategies that can be carried out by school principals to develop Islamic culture for schools characterized by Islam (Integrated Islam). The results of research conducted in all SMPs in Tanayan Raya Pekanbaru District, almost all school principals have implemented Islamic culture that is the hallmark of Integrated Islamic Schools (IT) including principals implementing policies to familiarize themselves with S3 (greetings, smiles, and greetings), getting used to shaking hands between teacher and teacher and with students, getting used to praying before and after learning, reading the Qur'an, getting used to praying the Dhuha Zhuhur and Asr in the congregation, Muhadarah. In addition to the above policy, the principle also applies the Exemplary method, familiarizes good things, enforces discipline, provides motivation, and cooperation with parents in upholding Islamic culture

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