History of Extracorporeal Membrane Oxygenation in Clinical Practice ～ Current Status and Issues ～

MEMBRANE ◽  
2019 ◽  
Vol 44 (6) ◽  
pp. 289-293
Author(s):  
Yuya Nobori ◽  
Masaki Anraku
Keyword(s):  
Clinical Practice ◽  
Extracorporeal Membrane Oxygenation ◽  
Current Status ◽  
Membrane Oxygenation ◽  
History Of

Current Status of Prolonged Extracorporeal Membrane Oxygenation for Acute Respiratory Failure

CHEST Journal ◽  
1973 ◽  
Vol 63 (5) ◽  
pp. 773-782 ◽  
Author(s):  
Edward A. Lefrak ◽  
Paul M. Stevens ◽  
George P. Noon ◽  
Michael E. DeBakey
Keyword(s):  
Respiratory Failure ◽  
Extracorporeal Membrane Oxygenation ◽  
Acute Respiratory Failure ◽  
Current Status ◽  
Membrane Oxygenation

scholarly journals Case Report. Extracorporeal Membrane Oxygenation in Nivolumab Associated Pneumonitis

2017 ◽  
Vol 3 (2) ◽  
pp. 84-88
Author(s):  
Thomas-Michael Schneider ◽  
Friederike Klenner ◽  
Franz Brettner
Keyword(s):  
Case Report ◽  
Extracorporeal Membrane Oxygenation ◽  
Therapeutic Option ◽  
High Dose ◽  
Great Success ◽  
Case Presentation ◽  
Computed Tomographic ◽  
Rehabilitation Hospital ◽  
Membrane Oxygenation ◽  
History Of

Abstract Background: Newly approved immunotherapeutic agents, like CTLA-4 inhibitors and antibodies against PD-1, are a promising therapeutic option in cancer therapy. Case presentation: A 74-year-old man, with a history of advanced stage melanoma and treatment with ipilimumab, pembrolizumab and nivolumab, was admitted to the hospital due to respiratory failure with hypoxemia and dyspnoea. He rapidly developed severe acute respiratory distress syndrome (ARDS), which required treatment in the intensive care unit which included mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Computed tomographic imaging (CT) showed signs of a pneumonitis, with an ARDS pattern related to the use of PD-1 antibodies. Treating the patient with high-dose immunosuppressive steroids led to an overall improvement. He was transferred to a rehabilitation hospital and subsequently to his home. Discussion and conclusion: This is a unique case report of a patient suffering a grade 4 adverse event under nivolumab who survived having been treated with ECMO. It highlights the possibility of associated adverse reactions as well as the use of ECMO in palliative care patients. ECMO can be of great success even in patients with malignancies, but careful decision making should be done on a case by case basis.

Favourable outcome after prolonged veno-venous extracorporeal membrane oxygenation (V-V ECMO) support for Pneumocystis jirovecii pneumonia in a renal transplant recipient

2021 ◽  
Vol 14 (4) ◽  
pp. e240004
Author(s):  
Daniel Kleinloog ◽  
Jacinta Maas ◽  
Jorge Lopez Matta ◽  
Carlos Elzo Kraemer
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Favourable Outcome ◽  
Pneumocystis Jirovecii ◽  
Lung Protective Ventilation ◽  
Pneumocystis Jirovecii Pneumonia ◽  
Partial Recovery ◽  
Ventilation Strategy ◽  
Membrane Oxygenation ◽  
Protective Ventilation Strategy ◽  
History Of

A 27-year-old man, with a history of renal transplantation, presented with acute kidney failure and Pneumocystis jirovecii pneumonia. The patient developed severe acute respiratory failure and required support by veno-venous extracorporeal membrane oxygenation for a total of 59 days. During this period, the patient had extremely low tidal volumes using a lung protective ventilation strategy and intermittent prone positioning was used to optimise oxygenation. There was full recovery of pulmonary and partial recovery of renal function.

The Development of Extracorporeal Membrane Oxygenation

2018 ◽  
Vol 84 (4) ◽  
pp. 587-592 ◽  
Author(s):  
Don K. Nakayama
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Heart Surgery ◽  
Life Support ◽  
Open Heart Surgery ◽  
Newborn Infants ◽  
Open Heart ◽  
Older Children ◽  
Membrane Oxygenation ◽  
Ann Arbor ◽  
History Of

Evolving from the development of heart-lung machines for open-heart surgery, extracorporeal membrane oxygenation has reemerged as a rescue modality for patients with acute respiratory failure that cannot be supported by conventional modes of ventilation. The history of extracorporeal membrane oxygenation begins with the discovery of heparin, fundamental to the success of extracorporeal circulation and membrane lungs. Engineers and scientists created suitable artificial membranes that allowed gas exchange while keeping gas and blood phases separate. Special pumps circulated blood through the devices and into patients without damage to delicate red cells and denaturing plasma. Initial attempts in adults ended in failure, but Robert Bartlett, first at Loma Linda, CA, then at Ann Arbor, MI, succeeded in applying the technology in newborn infants with persistent pulmonary hypertension. Preserved in the critical care of infants, the technology in time could be reapplied in the life support of older children and adults.

scholarly journals Use of Emergency Department Extracorporeal Membrane Oxygenation for Treatment of Acute Necrotizing Myocarditis

2019 ◽  
Vol 3 (1) ◽  
pp. 47-50
Author(s):  
Carly Loner ◽  
Peter Crane
Keyword(s):  
Emergency Department ◽  
Extracorporeal Membrane Oxygenation ◽  
Rare Complication ◽  
High Morbidity ◽  
Membrane Oxygenation ◽  
Acute Necrotizing ◽  
History Of ◽  
Eosinophilic Myocarditis ◽  
Systemic Symptoms

We report a case of acute necrotizing eosinophilic myocarditis (ANEM) secondary to drug rash with eosinophilia and systemic symptoms (DRESS) related to administration of minocycline. Myocarditis is a rare complication of DRESS and can manifest as either a self-limited hypersensitivity myocarditis or as the frequently fatal ANEM. Due to the high morbidity and mortality caused by this disease, emergency physicians should be aware of the potential of ANEM in patients with history of DRESS and new-onset cardiac dysfunction. This case reviews the clinical presentation and management of ANEM and the potential role of extracorporeal membrane oxygenation use in the emergency department.

Successful slide tracheoplasty and partial atrioventricular septal defect repair following extracorporeal membrane oxygenation support

2014 ◽  
Vol 25 (3) ◽  
pp. 573-575 ◽  
Author(s):  
Eoin M. Kelleher ◽  
Lars Nolke ◽  
Colin J. McMahon
Keyword(s):  
Myocardial Infarction ◽  
Extracorporeal Membrane Oxygenation ◽  
Septal Defect ◽  
Atrioventricular Septal Defect ◽  
Membrane Oxygenation ◽  
Slide Tracheoplasty ◽  
Defect Repair ◽  
History Of ◽  
Background History ◽  
Operative Recovery

AbstractA two-year-old boy with a background history of Down syndrome and partial atrioventricular septal defect presented with acute respiratory distress requiring intubation and mechanical ventilation. He continued to deteriorate, despite ventilation; direct laryngoscopy, bronchoscopy, and computed tomography demonstrated severe long segment tracheal stenosis. He was placed on extracorporeal membrane oxygenation to stabilise his condition. A slide tracheoplasty and complete repair of the partial atrioventricular septal defect was successfully undertaken. His post-operative recovery was complicated by myocardial infarction and stroke but he made a full recovery. This represents the first report of slide tracheoplasty and partial atrioventricular septal defect repair in a child following extracorporeal membrane oxygenation support.

Arcuate Incisions in Corneal Surgery

2013 ◽  
Vol 06 (01) ◽  
pp. 26
Author(s):  
Christopher L Blanton ◽  
Keyword(s):  
Clinical Practice ◽  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Current Status ◽  
Corneal Surgery ◽  
Future Developments ◽  
History Of ◽  
Correction Of Astigmatism ◽  
Indications For Use ◽  
Corneal Incisions

This article describes the current status of the femtosecond generated arcuate incision to correct corneal steepening. It covers the history of the surgical correction of astigmatism and describes the entrance of the femtosecond laser into modern corneal and cataract surgery. The process of photodisruption is explained as are the current indications for use of the femtosecond laser to make corneal incisions. A detailed narrative for programming the laser to perform arcuate incisions is included. Nomograms are referenced, and advantages over bladed incisions are described. A case is presented to show the use of these incisions in clinical practice. Finally, future developments are contemplated.

scholarly journals Oral Health of COVID-19 Patients Using Extracorporeal Membrane Oxygenation: A Clinical Study of 19 Cases

2021 ◽  
Vol 11 (1) ◽  
pp. 42
Author(s):  
Aya Yoshino ◽  
Yoshihiko Nakamura ◽  
Yuhei Irie ◽  
Taisuke Kitamura ◽  
Tohru Takata ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Oral Health ◽  
Extracorporeal Membrane Oxygenation ◽  
Univariate Analysis ◽  
Membrane Oxygenation ◽  
Health History ◽  
History Of ◽  
Health Deterioration

The oral health of coronavirus disease 2019 (COVID-19) patients in the intensive care unit (ICU) is an important issue in treatment of respiratory failure. We retrospectively investigated the oral health history of severe COVID-19 patients who received extracorporeal membrane oxygenation (ECMO) from April 2020 to December 2020 using the oral assessment guide from Fukuoka University (OAG-F). Nineteen consecutive patients (median age: 62 years) were divided into two groups according to survival (survivors, n = 12; non-survivors, n = 7). A univariate analysis revealed no significant differences between the groups in sex, age, body mass index (BMI), or the number of remaining teeth, whereas the ECMO assistance of non-survivors (median: 34 days) was prolonged in comparison to survivors (median: 8 days; p < 0.05). Among the factors of OAG-F, significant differences were observed between the groups in the conditions of the saliva, mucous membrane, and gingiva. The total scores in non-survivors (median: 19) were significantly higher in comparison to survivors (Median: 15.5), suggesting that the frequency of oral health deterioration was higher in non-survivors (p < 0.05). Taken together, these findings suggest that poor oral health is associated with mortality in COVID-19 patients receiving ECMO in the ICU.

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