The long-term effects of yoga and aerobic exercise on cognitive function and clinical symptoms in early psychosis : a follow-up randomized control trial

Author(s):  
Chung-ling, Pansy Chan
2011 ◽  
Vol 93 (3) ◽  
pp. 636-643 ◽  
Author(s):  
T. Pongcharoen ◽  
A. M. DiGirolamo ◽  
U. Ramakrishnan ◽  
P. Winichagoon ◽  
R. Flores ◽  
...  

2019 ◽  
Vol 19 (5) ◽  
pp. 513-515
Author(s):  
Sachiko Yamazaki ◽  
Chiaki Ura ◽  
Tsuyoshi Okamura ◽  
Masaya Shimmei ◽  
Taichi Ishiguro ◽  
...  

2021 ◽  
Author(s):  
Gustavo S. P. Pamplona ◽  
Jennifer Heldner ◽  
Robert Langner ◽  
Yury Koush ◽  
Lars Michels ◽  
...  

Neurofeedback allows for learning voluntary control over one's own brain activity, aiming to enhance cognition and clinical symptoms. A recent study improved sustained attention temporarily by training healthy participants to up-regulate the differential activity of the sustained attention network (SAN) minus the default mode network (DMN). However, long-term learning effects of functional magnetic resonance imaging (fMRI) neurofeedback training remain under-explored. Here, we evaluate the effects of network-based fMRI neurofeedback training for sustained attention by assessing behavioral and brain measures before, one day after, and two months after training. The behavioral measures include task as well as questionnaire scores, and the brain measures include activity and connectivity during self-regulation runs without feedback (i.e., transfer runs) and during resting-state runs. Neurally, we found that participants maintained their ability to control the differential activity during follow-up sessions. In resting-state runs and only in the follow-up, we observed higher connectivity within the DMN and higher degree of functional connectivity (FC) in regions that were successfully trained. We also show evidence for effects of training in the salience network mediating the switch between anticorrelated networks (the DMN and part of the SAN). Also, the training-induced increase in FC between the DMN and occipital gyrus was maintained during follow-up transfer runs. In contrast, the training-induced increased FC between DMN and occipital gyrus was not observed during follow-up resting-state runs. Behaviorally, we found that enhanced sustained attention right after training returned to baseline level during follow-up. The discrepancy between lasting regulation-related brain changes but transient behavioral and resting-state effects raises the question of how neural changes induced by neurofeedback training translate to potential behavioral improvements. Since neurofeedback directly targets brain measures to indirectly improve behavior long-term, a better understanding of the brain-behavior associations during and after neurofeedback training is needed to develop its full potential as a promising scientific and clinical tool.


Author(s):  
Henrik C. Bäcker ◽  
Chia H. Wu ◽  
Matthias R. G. Schulz ◽  
Thomas Sanjay Weber-Spickschen ◽  
Carsten Perka ◽  
...  

Abstract Introduction New app-based programs for postoperative rehabilitation have been developed, but no long-term study has been published to date. Thus, a prospective randomized control trial with 2-year follow-up was performed to evaluate the effectiveness of app-based rehabilitation (GenuSport) compared to a control group after total knee arthroplasty (TKA). Methods Between April and October 2016, 60 patients were enrolled in the study. Twenty-five patients were lost to follow-up, leaving 35 patients undergoing TKA for inclusion. In this group, twenty patients received app-based exercise program and 15 were randomized to the control group. The mean age was 64.37 ± 9.32 years with a mean follow-up of 23.51 ± 1.63 months. Patients in the app group underwent an app-based knee training starting on the day of surgery; whereas, patients in the control group underwent regular physiotherapy. Functional outcome scores using the Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Society Score (KSS) and VAS of pain were analyzed. Results In the short term, significant differences between the app group and control group in time of 10-m walk (19.66 ± 7.80 vs. 27.08 ± 15.46 s; p = 0.029), VAS pain at rest and activity (2.65 ± 0.82 vs. 3.57 ± 1.58, respectively 4.03 ± 1.26 vs. 5.05 ± 1.21; p < 0.05) were observed. In the long term, a variety of different tendencies was found, highest in KSS Function with 76.32 ± 16.49 (app group) vs. 67.67 ± 16.57 (control group) (p = 0.130). Additionally, patients in the app group required less painkillers (10.0% vs. 26.7%) and more likely to participate in sports (65.0% vs. 53.3%). Conclusions An app-based knee trainer is a promising tool in improving functional outcomes such as KSS function score and VAS after TKA. Level of evidence Level II, prospective randomized control trial.


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