Electro-osmotic flow and hydrodynamic dispersion in a channel with surface heterogeneities

2013 ◽  
Author(s):  
Qi Zhou
2013 ◽  
Vol 135 (10) ◽  
Author(s):  
Chiu-On Ng ◽  
Bo Chen

An analytical study is presented in this paper on hydrodynamic dispersion due to steady electro-osmotic flow (EOF) in a slit microchannel with longitudinal step changes of ζ potential. The channel wall is periodically patterned with alternating stripes of distinct ζ potentials. Existing studies in the literature have considered dispersion in EOF with axial nonuniformity of ζ potential only in the limiting case where the length scale for longitudinal variation is much longer than the cross-sectional dimension of the channel. Hence, the existing theories on EOF dispersion subject to nonuniform charge distributions are all based on the lubrication approximation, by which cross-sectional mixing is ignored. In the present study, the general case where the length of one periodic unit of wall pattern (which involves a step change of ζ potential) is comparable with the channel height, as well as the long-wave limiting case, are investigated. The problem for the hydrodynamic dispersion coefficient is solved numerically in the general case, and analytically in the long-wave lubrication limit. The dispersion coefficient and the plate height are found to have strong, or even nonmonotonic, dependence on the controlling parameters, including the period length of the wall pattern, the area fraction of the EOF-suppressing region, the Debye parameter, the Péclet number, and the ratio of the two ζ potentials.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ramin Zakeri

AbstractOne of the unresolved issues in physiology is how exactly myosin moves in a filament as the smallest responsible organ for contracting of a natural muscle. In this research, inspired by nature, a model is presented consisting of DPD (dissipative particle dynamics) particles driven by electro-osmotic flow (EOF) in micro channel that a thin movable impermeable polymer membrane has been attached across channel width, thus momentum of fluid can directly transfer to myosin stem. At the first, by validation of electro-osmotic flow in micro channel in different conditions with accuracy of less than 10 percentage error compared to analytical results, the DPD results have been developed to displacement of an impermeable polymer membrane in EOF. It has been shown that by the presence of electric field of 250 V/m and Zeta potential − 25 mV and the dimensionless ratio of the channel width to the thickness of the electric double layer or kH = 8, about 15% displacement in 8 s time will be obtained compared to channel width. The influential parameters on the displacement of the polymer membrane from DPD particles in EOF such as changes in electric field, ion concentration, zeta potential effect, polymer material and the amount of membrane elasticity have been investigated which in each cases, the radius of gyration and auto correlation velocity of different polymer membrane cases have been compared together. This simulation method in addition of probably helping understand natural myosin displacement mechanism, can be extended to design the contraction of an artificial muscle tissue close to nature.


Author(s):  
Mohammed Abdulhameed ◽  
Garba Tahiru Adamu ◽  
Gulibur Yakubu Dauda

In this paper, we construct transient electro-osmotic flow of Burgers’ fluid with Caputo fractional derivative in a micro-channel, where the Poisson–Boltzmann equation described the potential electric field applied along the length of the microchannel. The analytical solution for the component of the velocity profile was obtained, first by applying the Laplace transform combined with the classical method of partial differential equations and, second by applying Laplace transform combined with the finite Fourier sine transform. The exact solution for the component of the temperature was obtained by applying Laplace transform and finite Fourier sine transform. Further, due to the complexity of the derived models of the governing equations for both velocity and temperature, the inverse Laplace transform was obtained with the aid of numerical inversion formula based on Stehfest's algorithms with the help of MATHCAD software. The graphical representations showing the effects of the time, retardation time, electro-kinetic width, and fractional parameters on the velocity of the fluid flow and the effects of time and fractional parameters on the temperature distribution in the micro-channel were presented and analyzed. The results show that the applied electric field, electro-osmotic force, electro-kinetic width, and relaxation time play a vital role on the velocity distribution in the micro-channel. The fractional parameters can be used to regulate both the velocity and temperature in the micro-channel. The study could be used in the design of various biomedical lab-on-chip devices, which could be useful for biomedical diagnosis and analysis.


2018 ◽  
Vol 123 (5) ◽  
pp. 58006 ◽  
Author(s):  
J. Catalano ◽  
P. M. Biesheuvel

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