Quantification of physical activity as a function of offloading modality in patients with diabetic foot ulcers - A randomized cohort study

2012 ◽  
pp. BMP39
Author(s):  
Bijan Najafi ◽  
Manish Bharara ◽  
Gurtej Grewal ◽  
Robert Menzies ◽  
Talal K. Talal ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

Incidence and predictors of recurrent and other new diabetic foot ulcers: a retrospective cohort study

2019 ◽  
Vol 36 (11) ◽  
pp. 1417-1423 ◽  
Author(s):  
S. Engberg ◽  
K. Kirketerp‐Møller ◽  
H. Ullits Andersen ◽  
A. Rasmussen
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Diabetic Foot ◽  
Retrospective Cohort ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

scholarly journals Comment on “Ulcer‐free survival days and ulcer healing in patients with diabetic foot ulcers: A prospective cohort study”

2019 ◽  
Vol 17 (1) ◽  
pp. 228-229
Author(s):  
Amélie Simoneau ◽  
Laurence Blanco ◽  
Frédéric Domenge ◽  
Kamel Mohammedi ◽  
Ninon Foussard ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Ulcer Healing ◽  
Diabetic Foot ◽  
Prospective Cohort ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Free Survival

scholarly journals Ulcer‐free survival days and ulcer healing in patients with diabetic foot ulcers: A prospective cohort study

2019 ◽  
Vol 16 (6) ◽  
pp. 1365-1372 ◽  
Author(s):  
Afram Akturk ◽  
Jaap J. Netten ◽  
Rene Scheer ◽  
Marloes Vermeer ◽  
Jeff G. Baal
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Ulcer Healing ◽  
Diabetic Foot ◽  
Prospective Cohort ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Free Survival

scholarly journals Complexity of factors related to outcome of neuropathic and neuroischaemic/ischaemic diabetic foot ulcers: a cohort study

Diabetologia ◽  
2008 ◽  
Vol 52 (3) ◽  
pp. 398-407 ◽  
Author(s):  
M. A. Gershater ◽  
M. Löndahl ◽  
P. Nyberg ◽  
J. Larsson ◽  
J. Thörne ◽  
...  
Keyword(s):  
Cohort Study ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers

scholarly journals Early Advanced Therapy for Diabetic Foot Ulcers in High Amputation Risk Veterans: A Cohort Study

2020 ◽  
pp. 153473462092815
Author(s):  
Margaret Doucette ◽  
Kattie M. Payne ◽  
Walter Lough ◽  
Alison Beck ◽  
Kristi Wayment ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Diabetic Foot ◽  
Comprehensive Care ◽  
Foot Ulcers ◽  
Human Amniotic Membrane ◽  
Diabetic Foot Ulcers ◽  
Advanced Therapy ◽  
Advanced Therapies ◽  
The Impact

Veterans with diabetic foot ulcers (DFUs) represent the highest percentage of lower extremity amputations (LEAs) within the Veterans Affairs (VA) population. Many veterans have additional risk factors for amputation. Few studies focus on advanced therapies for this population. This study explores the impact of early application of dehydrated human amniotic membrane allograft (DAMA) with comprehensive care on preventing amputation. This prospective, single-center cohort study (ClinicalTrials.gov Identifier NCT02632929) was conducted through Boise VA Medical Center. Patients with DFUs were objectively stratified for LEA risk. Those with moderate to high amputation risk could participate. Participants received comprehensive care and weekly application of DAMA. Primary endpoint was avoidance of major LEA. Secondary endpoint was wound epithelialization. Monitoring continued 4 months. Between July 2015 and March 2017, 20 patients (mean age 67.2 years) with 24 DFU classified as moderate (12 wounds) to high risk (12 wounds) for amputation were enrolled. Wound volumes ranged from 0.072 cm3 to 56.4 cm3. Risk factors included neuropathy (20 patients), osteomyelitis (16 wounds), exposed tendon/ligament/bone (19 wounds), Charcot (5 patients), and peripheral arterial disease (13 wounds). All subjects avoided amputation within the study period, all 24 wounds achieved re-epithelialization within 4 to 33 weeks; mean healing time 13.2 weeks. Cost for the DAMA tissue ranged from $750 to $38 150. Estimated cost for LEA ranges from $30 000 to $50 000. No treatment-related adverse events during the study period were reported. The results suggest that early and frequent application of DAMA with comprehensive care may help prevent amputation. Additional research will help inform third-party payors and clinicians.

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