Effects of L-Carnitine on Long-Term Post Renal Ischemia and Reperfusion Injury in Rat

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Mehmet KANTER ◽  
Ömer YALÇIN ◽  
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Kadir KAYMAK
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Vol 94 (10S) ◽  
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T. Saat ◽  
T. van Ginhoven ◽  
M. Verweij ◽  
J. N.M. IJzermans ◽  
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2014 ◽  
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pp. 55-60 ◽  
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Bruno Leonardo de Freitas Soares ◽  
Maria Andréia Lopes de Freitas ◽  
Edna Frasson de Souza Montero ◽  
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Fausto Miranda Júnior

2006 ◽  
Vol 6 (13-14) ◽  
pp. 1966-1972 ◽  
Author(s):  
Giselle Martins Gonçalves ◽  
Marcos Antônio Cenedeze ◽  
Carla Quarim Feitoza ◽  
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Georgia Daniela Macusso ◽  
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Reinaldo C. Silva ◽  
Joilson O. Martins ◽  
Maristella A. Landgraf ◽  
Vanessa N. Paiva ◽  
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Vol 9 (1) ◽  
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Gertrude J. Nieuwenhuijs-Moeke ◽  
Søren E. Pischke ◽  
Stefan P. Berger ◽  
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Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation. Long term, it is associated with acute rejection and chronic graft dysfunction due to interstitial fibrosis and tubular atrophy. Recently, more insight has been gained in the underlying molecular pathways and signalling cascades involved, which opens the door to new therapeutic opportunities aiming to reduce IRI and improve graft survival. This review systemically discusses the specific molecular pathways involved in the pathophysiology of IRI and highlights new therapeutic strategies targeting these pathways.


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Vol 26 (1) ◽  
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Zijun Wang ◽  
Janet L. Colli ◽  
Christopher Keel ◽  
Kayleen Bailey ◽  
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...  

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