scholarly journals Submandibular gland enlargement

2021 ◽  
Author(s):  
Yahya Baba
Keyword(s):  
Submandibular Gland ◽  
Gland Enlargement

scholarly journals A case of primary biliary cirrhosis associated with lacrimal gland and submandibular gland enlargement, and chronic pancreatitis.

Kanzo ◽  
1987 ◽  
Vol 28 (5) ◽  
pp. 623-627
Author(s):  
Shinichiro YAMAMOTO ◽  
Itsuro SAITO ◽  
Ryosuke YAMAMOTO ◽  
Seiji IDEGUCHHI ◽  
Kenji OHMOTO ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Primary Biliary Cirrhosis ◽  
Submandibular Gland ◽  
Lacrimal Gland ◽  
Biliary Cirrhosis ◽  
Gland Enlargement

scholarly journals Bilateral submandibular gland agenesis with bilateral parotid hypertrophy: a rare presentation

2016 ◽  
Vol 2 (3) ◽  
pp. 161
Author(s):  
Rakhi Kumari ◽  
Priyanko Chakraborty ◽  
Sidharth Pradhan ◽  
Purnima Joshi ◽  
Rajiv Kumar Jain
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Submandibular Gland ◽  
Recurrent Laryngeal Nerve Injury ◽  
Laryngeal Nerve ◽  
Compensatory Mechanism ◽  
Rare Presentation ◽  
Case Presentation ◽  
Laryngeal Nerve Injury ◽  
Gland Enlargement

<p class="abstract"><span lang="EN-IN">Recurrent laryngeal nerve injury and hypoparathyroidism are two of the much discussed major complications Bilateral submandibular gland aplasia associated with bilateral hypertrophy of parotid gland is one of the rarest case presentation. The enlargement of parotid gland is mostly due to a compensatory mechanism of submandibular aplasia. This case report describes a 45 year female presented with diffuse swelling over bilateral preauricular and infraauricular area. CECT of face confirmed diffuse bilateral parotid gland enlargement associated with absence of submandibular gland.</span></p>

scholarly journals P27 Lymphoma-mimicker of IgG4-related dacryoadenitis and sialadenitis

2021 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
Taha Akhtar
Keyword(s):  
Case Report ◽  
Submandibular Gland ◽  
Low Grade ◽  
Fine Needle Aspirate ◽  
Lacrimal Glands ◽  
Related Disease ◽  
Igg4 Related Disease ◽  
Mikulicz Disease ◽  
History Of ◽  
Gland Enlargement

Abstract Case report - Introduction Major salivary gland (sialadenitis) and lacrimal gland (dacryoadenitis) involvement can be a common feature of IgG4-related disease. There can be involvement of lacrimal and parotid gland which was previously called as Mikulicz disease and/or submandibular gland enlargement which was previously called Küttner tumour. These were previously mistakenly considered to be subcategories of Sjogren’s syndrome, but are now classified as IgG4-related disease. Here we discuss a case report of a patient who presented with bilateral dacryoadenitis and unilateral submandibular gland enlargement which initially was thought to be IgG4-related disease but turned out to be low-grade lymphoma. Case report - Case description A 15-year-old boy presented with 6-month history of bilateral eyelid swelling. The swelling was more on the lateral side of the eyelids and was painless. It had come on suddenly over a couple of days. No history of weight loss, dry eyes, dry mouth, joint issues or skin rashes or any other symptoms. Physical examination revealed bilateral ptosis, no visual impairment and systemic examination revealed an enlarged right submandibular gland. He had initially been to a local hospital where he had investigations which included autoimmune screen including ANA, ENA, ANCA, dsDNA, serum ace and complement levels which were all negative. C1 esterase inhibitor was normal. Routine bloods including complete blood count, urea and electrolytes, thyroid stimulating hormone and erythrocyte sedimentation rate were within normal limits. Urine albumin to creatinine ratio was not raised. Hepatitis serology including Hepatitis B & C and HIV was negative. Ultrasound abdomen was unremarkable. CT scan of orbits showed bilateral enlarged lacrimal glands with patchy post contrast enhancement and the glands extending up to insertion of lateral rectus muscle. CT chest some enlarged axillary lymph nodes and nodes in lung query infective etiology. CT abdomen and pelvis was unremarkable. Ultrasound neck showed right submandibular node enlargement with colour doppler showing increased vascularity. Fine needle aspirate of the submandibular gland showed reactive lymphoid hyperplasia. He was given two short courses of steroids and each time the swelling rapidly responded to the steroids but recurred on cessation of the steroids. IgG subset analyses revealed elevated IgG4 levels of 1152mg/dl. The differential here was IgG4-related disease but as there was no clear tissue diagnosis a core biopsy of the right submandibular gland was done. This revealed tissue suspicious of low grade (extranodal marginal zone and mucosa-associated lymphoid tissue [MALT]) lymphoma and excision biopsy was performed for definitive diagnosis. Case report - Discussion IgG4-related disease is an immune mediated fibroinflammatory condition which can affect a variety of organs and can present as tumour-like enlargement and/or organ dysfunction. The pathological findings in IgG4-related disease are lymphoplasmocytic infiltrates of IgG4-positive cells along with increased levels of serum IgG4 levels. Salivary and lacrimal glands can be commonly affected and present as enlargement, which is usually painless and bilateral. The combination of lacrimal gland enlargement with both parotid and submandibular gland enlargement is called IgG4-related Mikulicz disease. Apart from salivary glands, another commonly affected organ is the pancreas which can present as a pancreatic mass and painless jaundice, sclerosing cholangitis, retroperitoneal fibrosis, aortitis and periaortitis. Less commonly it can affect thyroid, kidney and lungs. Early recognition, diagnoses and treatment is important due to the fibroinflammatory nature of the disease. Malignancy is always in the differential and should be excluded. Steroids are the mainstay of treatment. If patients experience flare, rituximab can be added. Diagnosis should be confirmed with biopsy but histopathological findings are never alone diagnostic of IgG4-related disease and should be interpreted with clinical, serological and radiological findings. Case report - Key learning points Although this patient had typical presentation of IgG4-related disease with painless enlargement of salivary and lacrimal glands and elevated IgG4 serum levels, biopsy was imperative to get to the diagnoses of low-grade lymphoma and fine needle aspirate was not adequate. As mentioned above, biopsy in IgG4-related disease will confirm the diagnosis provided there are other supporting features (radiological and serological). However, it is imperative for excluding other important diseases like lymphoproliferative disorders.

Submandibular Gland Enlargement Which Appeared Immediately after Insertion of Intubating LMA: Two case reports

2003 ◽  
Vol 44 (5) ◽  
pp. 717 ◽  
Author(s):  
Han Seok Park ◽  
Choon Hak Lim ◽  
Hye Won Lee ◽  
Hun Cho ◽  
Ji Yong Park ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Case Reports ◽  
Gland Enlargement

Cytochemical Evidence for Presynatic β-Adrenergic Regulation of Secretion in the Developing Rat Submandibular Gland

1977 ◽  
Vol 35 ◽  
pp. 430-431
Author(s):  
L.S. Cutler
Keyword(s):  
Cyclic Amp ◽  
Adenylate Cyclase ◽  
Submandibular Gland ◽  
Neonatal Rat ◽  
Cyclase Activity ◽  
Adenylate Cyclase Activity ◽  
Parotid Glands ◽  
Adrenergic Agonist ◽  
Rat Submandibular Gland

Many studies previously have shown that the B-adrenergic agonist isoproterenol and the a-adrenergic agonist norepinephrine will stimulate secretion by the adult rat submandibular (SMG) and parotid glands. Recent data from several laboratories indicates that adrenergic agonists bind to specific receptors on the secretory cell surface and stimulate membrane associated adenylate cyclase activity which generates cyclic AMP. The production of cyclic AMP apparently initiates a cascade of events which culminates in exocytosis. During recent studies in our laboratory it was observed that the adenylate cyclase activity in plasma membrane fractions derived from the prenatal and early neonatal rat submandibular gland was retractile to stimulation by isoproterenol but was stimulated by norepinephrine. In addition, in vitro secretion studies indicated that these prenatal and neonatal glands would not secrete peroxidase in response to isoproterenol but would secrete in response to norepinephrine. In contrast to these in vitro observations, it has been shown that the injection of isoproterenol into the living newborn rat results in secretion of peroxidase by the SMG (1).

Biogenesis of Catalase-Positive Rods in Excretory Duct Cells of Salivary Glands

1976 ◽  
Vol 34 ◽  
pp. 62-63
Author(s):  
Dwight K. Romanovicz ◽  
Jacob S. Hanker
Keyword(s):  
Light Microscopy ◽  
Salivary Glands ◽  
Submandibular Gland ◽  
Excretory Duct ◽  
Exocrine Glands ◽  
Duct Cells ◽  
Peroxidatic Activity ◽  
Microscopic Studies ◽  
Different Dimensions

The presence of catalase-positive rods (Fig. 1) of different dimensions, which frequently have a crystalline appearance by light microscopy, has been reported. They seem to be related to peroxisomes which were characterized morphologically and cytochemically in parotid and other exocrine glands of the rat by Hand in 1973. Our light microscopic studies of these spherical microbodies and rods of different sizes, stained by virtue of the peroxidatic activity of their catalase, indicate that they are almost entirely confined to the cells of the striated and execretory ducts of the submandibular gland in the mouse. The rods were usually noted only in the proximity of the ductal microbodies. The latter frequently showed a tendency to appear in linear close array, or even to be contiguous (Fig. 2). This suggested that the rods could be formed by the fusion of microbodies.

Sign in / Sign up

Export Citation Format

Share Document