scholarly journals EBV associated smooth muscle tumour

2021 ◽  
Author(s):  
Henry Knipe ◽  
Irvine Sihlahla
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Tumour

Unusual morphological features of uterine leiomyomas treated with progestogens

2011 ◽  
Vol 64 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Clinton Boyd ◽  
W Glenn McCluggage
Keyword(s):  
Smooth Muscle ◽  
Mitotic Activity ◽  
Intrauterine Device ◽  
Malignant Potential ◽  
Morphological Features ◽  
Uterine Leiomyomas ◽  
Pathological Features ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Benign Leiomyoma

BackgroundUterine leiomyomas are extremely common in surgical pathology practice and in the vast majority there are no issues in diagnosis. Progestogens are widely prescribed drugs for a variety of indications, including abnormal uterine bleeding, and are often given to women with leiomyomas but the pathological features of leiomyomas treated with progestogens are poorly described.MethodsWe report the pathological features in eight cases of uterine leiomyomas in women who had been treated with oral progestogens or a progestogen-containing intrauterine device; all cases were received in consultation because the features raised concern for leiomyosarcoma, smooth muscle tumour of uncertain malignant potential or a benign leiomyoma with unusual features. Additionally, we reviewed a series of cases of uterine leiomyomas (n=99) in women who exhibited progestogenic effects in the endometrium.ResultsThe morphological features in the consult cases, which were widespread and marked and which varied somewhat from case to case, included small and/or large areas of infarct-type necrosis (sometimes mimicking coagulative tumour cell necrosis) with surrounding increased cellularity, mitotic activity, nuclear pyknosis, cytoplasmic eosinophilia, epithelioid morphology, stromal oedema, haemorrhage, and myxoid change and infiltration by CD56 positive granulated lymphocytes. Sometimes the features resulted in an almost deciduoid appearance. Similar features were present to a minor degree in significant numbers of the additional series of cases.ConclusionsPathologists should be aware of these progestogen-associated features when reporting uterine leiomyomas whether or not the clinician has indicated that the woman is taking progestogens since otherwise a diagnosis of leiomyosarcoma or smooth muscle tumour of uncertain malignant potential may be rendered. Useful features in suggesting a benign leiomyoma, in addition to recognition of the morphological features described which, in combination, are characteristic of progestogens, are the lack of true nuclear atypia and the low mitotic activity away from the abnormal areas.

PERFORATED JEJUNAL DIVERTICULUM CONTAINING A SMOOTH MUSCLE TUMOUR

1982 ◽  
Vol 52 (1) ◽  
pp. 89-92 ◽  
Author(s):  
CHRISTOPHER S. WORTHLEY ◽  
GLYNN G. JAMIESON ◽  
LESLEY A. SMITH
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Tumour ◽  
Jejunal Diverticulum

Cutaneous Leiomyoma: A Clinical Study of 152 Patients

Dermatology ◽  
2021 ◽  
pp. 1-7
Author(s):  
Joaquim Marcoval ◽  
Clàudia Llobera-Ris ◽  
Carlos Moreno-Vílchez ◽  
Rosa María Penín
Keyword(s):  
Smooth Muscle ◽  
Medical Records ◽  
Cell Cancer ◽  
Fumarate Hydratase ◽  
Upper Extremities ◽  
Resection Margins ◽  
Smooth Muscle Tumour ◽  
Skin Tumours ◽  
Hereditary Leiomyomatosis

<b><i>Background:</i></b> Cutaneous leiomyoma (CL) is a benign smooth muscle tumour included in painful skin tumours. Multiple CLs are cutaneous markers of hereditary leiomyomatosis and renal cell cancer (HLRCC). <b><i>Objectives:</i></b> To retrospectively review our series of patients with CLs to analyse their clinical features and the association with HLRCC. <b><i>Methods:</i></b> Cases coded as CL in the database of the pathology department between 2004 and 2019 were included in the study. Medical records were retrospectively reviewed to obtain the following data: age, sex, location, number of lesions, diameter, evolution time at diagnosis, suspected clinical diagnosis, tenderness, status of resection margins, development of recurrence, follow-up time, and association with HLRCC. <b><i>Results:</i></b> 152 patients had CLs, 89 women and 63 men, mean age 56.26, SD 16.030 years. Subtypes were piloleiomyoma in 62 patients, angioleiomyoma in 80, and genital leiomyoma in 10. All of our 11 patients with multiple lesions corresponded to piloleiomyomas, and HLRCC was confirmed in 8 of them (73%). Patients with HLRCC were younger than patients with piloleiomyomas without HLRCC (34.88 vs. 56.17 years, <i>p</i> = 0.009). Vascular and genital leiomyomyomas were solitary and were not associated with HLRCC. <b><i>Conclusion:</i></b> In patients with multiple piloleiomyomas HLRCC must be ruled out as it is confirmed in a high proportion of cases. The probability of fumarate hydratase mutation is greater in multiple piloleiomyomas involving both the trunk and upper extremities in the same patient.

EBV Smooth Muscle Tumour

2019 ◽  
pp. 257-261
Author(s):  
Stephanie Ming Young ◽  
Shantha Amrith ◽  
Eric Ting ◽  
Bingcheng Wu ◽  
Min En Nga ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Tumour

Epstein–Barr virus-associated smooth muscle tumour mimicking bilateral vocal process granuloma

2007 ◽  
Vol 122 (1) ◽  
pp. 100-104 ◽  
Author(s):  
E C Gan ◽  
D P C Lau ◽  
K L Chuah
Keyword(s):  
Smooth Muscle ◽  
Epstein Barr Virus ◽  
English Literature ◽  
High Dose ◽  
Smooth Muscle Tumour ◽  
Barr Virus ◽  
Vocal Process ◽  
Epstein Barr ◽  
Laser Excision ◽  
End Stage

AbstractA case is presented of a 36-year-old Chinese woman with a renal transplant for end-stage renal failure due to Goodpasture's syndrome. She presented with a year's history of throat discomfort and acid regurgitation into her throat. Videolaryngoscopy revealed bilateral vocal process granuloma, presumed to be due to gastroesophageal reflux. A four-week course of high dose omeprazole was prescribed. On follow up a month later, the granulomas had enlarged, and laser excision was undertaken. Histological and immunohistochemical staining was consistent with Epstein–Barr virus-associated smooth muscle tumour. This is believed to be the first reported case in the English literature of such a tumour affecting the vocal process. The aim of this paper is to present the pathogenesis, clinical behaviour and treatment of Epstein–Barr virus-associated smooth muscle tumour, and to review the literature concerning the differential diagnosis of polypoid vocal process lesions.

scholarly journals Duodenal Leiomyosarcoma Mimicking a Pancreatic Pseudocyst

HPB Surgery ◽  
1994 ◽  
Vol 8 (1) ◽  
pp. 49-52 ◽  
Author(s):  
C. Sperti ◽  
C. Pasquali ◽  
F. Di Prima ◽  
R. Baffa ◽  
S. Pedrazzoli
Keyword(s):  
Smooth Muscle ◽  
Pancreatic Pseudocyst ◽  
Frozen Section ◽  
Exploratory Laparotomy ◽  
Cystic Mass ◽  
Tumour Markers ◽  
Cyst Fluid ◽  
Radiological Findings ◽  
Smooth Muscle Tumour

A case of duodenal leiomyosarcoma presenting as a cystic mass is reported. Amylase, tumour markers levels in the cyst fluid and radiological findings suggested an inflammatory pancreatic pseudocyst. Exploratory laparotomy and frozen section examination showed a smooth muscle tumour of the duodenum. Pancreatoduodenectomy with pylorus-preser vation was performed and the patient remained symptom-free at 8 months follow-up.

2. Epstein-barr virus associated smooth muscle tumour; rare soft tissue tumour

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S133
Author(s):  
Yalda Hakemi ◽  
Amir Hadji-Ashrafy ◽  
Vishnu Subramanian
Keyword(s):  
Smooth Muscle ◽  
Soft Tissue ◽  
Epstein Barr Virus ◽  
Soft Tissue Tumour ◽  
Smooth Muscle Tumour ◽  
Barr Virus ◽  
Tissue Tumour ◽  
Epstein Barr

An unusual cause of a multifocal bone lesion: Epstein–Barr Virus-Associated Smooth Muscle Tumour (EBV-SMT) involving bone

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S65
Author(s):  
Sameer Ansar ◽  
Richard Boyle ◽  
Wendy Brown ◽  
Rooshdiya Karim ◽  
Peter Luk ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Epstein Barr Virus ◽  
Bone Lesion ◽  
Smooth Muscle Tumour ◽  
Barr Virus ◽  
Epstein Barr
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