scholarly journals Parosteal osteosarcoma

2021 ◽  
Author(s):  
Mostafa El-Feky ◽  
Ian Bickle
Keyword(s):  
Parosteal Osteosarcoma

scholarly journals Parosteal Osteosarcoma with Pancreatic Metastasis and Multiple Relapses: A Case Report and Review of the Literature

2021 ◽  
pp. 983-988
Author(s):  
Daniel Cirotski ◽  
Jyoti Panicker
Keyword(s):  
Age Groups ◽  
Bone Cancer ◽  
Pancreatic Metastasis ◽  
Low Grade ◽  
Parosteal Osteosarcoma ◽  
Disease Course ◽  
Review Of The Literature ◽  
Histologic Subtype ◽  
Primary Bone ◽  
Multiple Relapses

Osteosarcoma is the most common primary bone cancer in all age groups. Metastasis mostly occurs with high-grade tumors disseminating to the lungs and other bones. Spread to the pancreas is rare and undocumented in the low-grade subtypes. Additionally, it is uncommon for the disease course of low-grade subtypes to involve multiple relapses. We present a 35-year-old woman with parosteal osteosarcoma who has experienced an atypical metastasis to the pancreas as well as multiple local and pulmonary relapses. The lesion was identified incidentally on routine imaging, and the patient underwent resection. We compare our case to the other reports of pancreatic metastasis in the literature. Despite being especially rare, clinicians ought to be aware of pancreatic metastasis of osteosarcoma. Furthermore, despite parosteal osteosarcoma’s less aggressive disease course, it can uncommonly lead to multiple relapses. We present a rare case exemplifying these phenomena in the prognostically favorable histologic subtype of parosteal osteosarcoma.

Giant Synovial Chondromatosis of the Knee Mimicking a Parosteal Osteosarcoma: A Case Report

2010 ◽  
Vol 16 (2) ◽  
pp. 95
Author(s):  
Chang Ho Kang ◽  
Jong Hoon Park ◽  
Dae Hee Lee ◽  
Chul Hwan Kim ◽  
Jeong Mi Park ◽  
...  
Keyword(s):  
Case Report ◽  
Synovial Chondromatosis ◽  
Parosteal Osteosarcoma

Treatment and outcome of parosteal osteosarcoma: Biological versus endoprosthetic reconstruction

2011 ◽  
Vol 103 (8) ◽  
pp. 782-789 ◽  
Author(s):  
Philipp T. Funovics ◽  
Frederik Bucher ◽  
Cyril D. Toma ◽  
Rainer I. Kotz ◽  
Martin Dominkus
Keyword(s):  
Parosteal Osteosarcoma ◽  
Endoprosthetic Reconstruction

scholarly journals A case of parosteal osteosarcoma of the mandibular gingiva.

1995 ◽  
Vol 41 (10) ◽  
pp. 866-868
Author(s):  
Hiroyuki MATSUDA ◽  
Hiroyoshi HIRATSUKA ◽  
Takashi SEKIGUCHI ◽  
Kiyoshi HONMA ◽  
Yasushi HARIYA ◽  
...  
Keyword(s):  
Parosteal Osteosarcoma

Protease Expression in Dedifferentiated Parosteal Osteosarcoma

1999 ◽  
Vol 123 (3) ◽  
pp. 213-221
Author(s):  
Carsten Haeckel ◽  
Alberto G. Ayala ◽  
Kathrin Radig ◽  
A. Kevin Raymond ◽  
Albert Roessner ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Cathepsin B ◽  
Proteolytic Enzymes ◽  
Expression Patterns ◽  
Metastatic Potential ◽  
Cell Surface Receptor ◽  
Parosteal Osteosarcoma ◽  
Surface Receptor ◽  
Bone Trabeculae ◽  
Immunohistochemical Techniques

Abstract Background.—Parosteal osteosarcoma with dedifferentiation provides a useful model to study tumor progression from an indolent locally aggressive neoplasm to highly lethal metastasizing malignancy. Up-regulation of the proteolytic enzymes participating in stromal degradation is known to promote invasive growth and metastasis of several human and experimental tumors. Methods.—The expression patterns of urokinasase plasminogen activator (u-PA), its cell-surface receptor (u-PAR), and cathepsin B were analyzed by immunohistochemical techniques in 11 cases of parosteal osteosarcoma and in 4 cases of dedifferentiated parosteal osteosarcoma. Results.—Both enzymes and the receptor were coexpressed in most tumor cells of parosteal and dedifferentiated parosteal osteosarcoma. Their expression was strikingly enhanced in the dedifferentiated high-grade component of the tumors. Tumor cells involved in bone production (ie, those adjacent to tumor produced bone trabeculae) exhibited equally strong expression of u-PA, u-PAR, and cathepsin B, regardless of their histologic grade. Expression of u{-}PA, u-PAR, and cathepsin B was undetectable in the “normalized” cells embedded in the well-developed tumor bone trabeculae. Conclusion.—These data indicate that u-PA and its interacting molecules, such as u-PAR and cathepsin B, may have some contributory effects on the metastatic potential of tumor cells in dedifferentiated parosteal osteosarcoma.

The meaning of radiolucencies in parosteal osteosarcoma.

1985 ◽  
Vol 67 (6) ◽  
pp. 901-910 ◽  
Author(s):  
F Bertoni ◽  
D Present ◽  
T Hudson ◽  
W F Enneking
Keyword(s):  
Parosteal Osteosarcoma

Medullary involvement in parosteal osteosarcoma. A case report.

1987 ◽  
Vol 69 (1) ◽  
pp. 131-136 ◽  
Author(s):  
P Picci ◽  
M Campanacci ◽  
G Bacci ◽  
R Capanna ◽  
A Ayala
Keyword(s):  
Case Report ◽  
Parosteal Osteosarcoma

Parosteal Osteosarcoma

2010 ◽  
pp. 359-360
Author(s):  
Javad Parvizi ◽  
Gregory K. Kim
Keyword(s):  
Parosteal Osteosarcoma

Clinical Outcome of Parosteal Osteosarcoma

2013 ◽  
Vol 19 (1) ◽  
pp. 20 ◽  
Author(s):  
Won Seok Song ◽  
Dae-Geun Jeon ◽  
Wan Hyeong Cho ◽  
Chang Bae Kong ◽  
Sang Hyun Cho ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Parosteal Osteosarcoma
Sign in / Sign up

Export Citation Format

Share Document