scholarly journals Calcium volume score

2020 ◽  
Author(s):  
Joachim Feger
Keyword(s):  
Volume Score

Abstract 021: Greater Calcium Density of Coronary Artery Plaque is Protective for Cardiovascular Events. The Multi-Ethnic Study of Atherosclerosis

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Michael H Criqui
Keyword(s):  
Coronary Artery ◽  
Standard Deviation ◽  
Proportional Hazards Model ◽  
Hazard Ratio ◽  
Calcium Deposition ◽  
Agatston Score ◽  
Standard Deviation Increase ◽  
Density Score ◽  
Independent Association ◽  
Volume Score

Background— Coronary artery calcium (CAC) measured by computed tomography (CT) has strong predictive value for incident cardiovascular disease (CVD) events. The standard CAC score is the Agatston, which is the product of the within slice CAC plaque area and a plaque specific density factor of 1, 2, 3, or 4, summed for all CT slices. Thus, the Agatston score is weighted upward for greater CAC density. However, data from both observational studies and randomized trials suggest increased CAC density per se may be protective for CVD. Methods— In a multi-ethnic population of 3398 men and women with Agatston scores > 0 at baseline, we derived a formula using the individual Agatston scores and the volume scores to create a per participant CAC density score. We then analyzed the independent associations of CAC volume and CAC density with incident hard CVD, defined as MI, resuscitated cardiac arrest, cardiac death, stroke, or stroke death, Results— During a median of 7.6 years of follow-up, there were 265 hard CVD events, 175 of which were coronary heart disease (CHD) events. In a proportional hazards model including the General Framingham Risk Score (GFRS) and both the CAC volume and CAC density score, the CAC volume score showed a strong independent association with incident CVD, with a hazard ratio per natural log standard deviation increase of 1.62, p<.0001. Conversely, the CAC density score showed an independent association that was strongly protective for CVD, with a hazard ratio per standard deviation increase of 0.72, p<.0003. Multivariate quartile analyses showed that at any given volume score, a density score in the 4 th quartile (range 3.2 to 4.0) decreased the risk of a CVD event by 51%, p=.002. The density score showed no significant interactions with either sex or ethnicity. The addition of the volume score to the model containing the GFRS increased the area under the ROC curve (AUC) from 0.664 to 0.6869, p=.015, and further addition of the density score increased the AUC to .6994, p=.023. Separate analyses limited to CHD events showed similar results. Conclusions— At any given volume of CAC, increased density in calcified coronary plaques is protective for incident CVD, consistent with the concept that calcium deposition may increase the stability of atherosclerotic plaques. CAC scoring systems should be modified to weight downward for density rather than upward, and thus improve CVD risk prediction.

scholarly journals Sonographic Assessment of Intravascular Fluid Estimate (SAFE) Score by Using Bedside Ultrasound in the Intensive Care Unit

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Keith Killu ◽  
Victor Coba ◽  
Dionne Blyden ◽  
Semeret Munie ◽  
Darlene Dereczyk ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Scoring System ◽  
Venous Pressure ◽  
Tertiary Care ◽  
Bedside Ultrasound ◽  
Volume Status ◽  
Surgical Intensive Care Unit ◽  
Surgical Intensive Care ◽  
Volume Score

Objective. The objective of the study was to use an ultrasound-based numerical scoring system for assessment of intravascular fluid estimate (SAFE) and test its validity. Methods. A prospective, observational study was carried out in the surgical intensive care unit (ICU) of an urban tertiary care teaching hospital. Patient’s intravascular volume status was assessed using the standard methods of heart rate, blood pressure, central venous pressure, cardiac output, lactate and saturation of venous oxygen, and others. This was compared with assessment using bedside ultrasound evaluation of the cardiac function, inferior vena cava, lungs, and the internal jugular vein. Applying a numerical scoring system was evaluated by Fisher’s exact testing and multinomial logistic model to predict the volume status based on ultrasound scores and the classification accuracy. Results. 61 patients in the ICU were evaluated. 21 (34.4% of total) patients diagnosed with hypovolemia, and their ultrasound volume score was −4 in 14 (66.7%) patients, −3 in 5 (23.8%) patients, and 0 in 2 (9.5%) patients (p<0.001). 18 (29.5% of total) patients diagnosed with euvolemia, and their ultrasound volume score was 0 in 11 (61.1%) patients, +1 in 4 (22.2%) patients, and −1 in 1 (5.6%) patient (p<0.001). 22 (36.1% of total) patients diagnosed with hypervolemia, and their ultrasound volume score was +4 in 4 (18.2%) patients, +3 in 15 (68.2%) patients, and  + 1 in 1 (4.6%) patient (p<0.001). We found a strong association between standard measures and the ultrasound score (p<0.001). Conclusion. Using the SAFE scoring system to identify the IVV status in critically ill patients significantly correlates with the standard measures. A SAFE score of −4 to −2 more likely represents hypovolemia, −1 to +1 more likely represents euvolemia, and +2 to +4 more likely to be hypervolemia.

scholarly journals The value of prostate-specific antigen-age volume score in predicting prostate cancer in Taiwan

2020 ◽  
Vol 31 (4) ◽  
pp. 163
Author(s):  
Jhen-Hao Jhan ◽  
Chun-Hsuan Lin ◽  
Che-Wei Chang ◽  
Wei-Ming Li ◽  
Shen-Chen Wen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Volume Score

scholarly journals C.F.E. Hornemans “Aladdin” – en mishandlet opera

2014 ◽  
Vol 49 ◽  
Author(s):  
Inger Sørensen
Keyword(s):  
Publishing House ◽  
Good Reason ◽  
Early Years ◽  
Sheet Music ◽  
Music Publishing ◽  
Rightful Place ◽  
Edvard Grieg ◽  
Dramatic Music ◽  
Volume Score

NB: Artiklen er på dansk, kun resuméet er på engelsk. The Danish composer C.F.E. Horneman (1840-1906) was himself of the opinion that his talent as a composer was particularly for dramatic music. And he had good reason. He began his undisputed masterwork, the opera “Aladdin”, when he was little more than 20 years old, having just returned home from studying in the music metropolis of Leipzig. He worked on the score for most of his life. There are several reasons for this. During the early years, the work proceeded well but, when Horneman’s father died in 1870, he had to put the score aside, take over their music publishing house and set about earning his living. Finally, after several failed endeavours as a concert organiser and conductor, Horneman found his place in Danish music life in 1879, as the head of his own music institute. But this took up so much of his time that he only rarely had the opportunity to compose, even though he considered this to be his main calling. It was only in 1883, when various personalities in the Danish music world, and Horneman’s friend, Edvard Grieg, arranged to have him granted a yearly state subsidy, that he was once again able to take up the “Aladdin” score. And yet it took another five years before he could submit the finished score to the Royal Theatre. Even though the sensors were satisfied with the music, Benjamin Feddersen’s libretto, based on the story from “A Thousand and One Nights”, caused problems. And so the production was shelved. Then, in the fall of 1888, the theatre decided to stage the opera at a gala performance on the occasion of Christian IX’s jubilee. This decision proved to be catastrophic for the opera. Only six weeks were allocated to rehearse this large and complicated work, resulting in various rash cuts. The opening night was a fiasco. The royal audience had no appreciation of this new Danish opera and the production left much to be desired. It was only 14 years later that Horneman achieved satisfaction, when a new, severely revised version was produced in 1902. It enjoyed full houses but, in spite of its success, the opera has never since been professionally performed in its entirety. The sheet music archived in the Royal Library clearly shows how much Horneman worked on the material from the onset. The four-volume score contains so many corrections and deletions that it could hardly be used as a production score. At the time of writing, the score from the 1888 production, which was in a terrible state of preservation, is being restored. The archived material is in such bad condition that a new, practical, scholarly version of “Aladdin” is needed if Horneman’s masterwork is to regain its rightful place in the Danish opera repertoire.

The Relation of Calcium Volume Score and Stenosis of Carotid Artery

2020 ◽  
Vol 29 (1) ◽  
pp. 104493 ◽  
Author(s):  
Maryam Moradi ◽  
Mohammad Mehdi Baradaran Mahdavi ◽  
Mehdi Karami Nogourani
Keyword(s):  
Carotid Artery ◽  
Volume Score

scholarly journals Association of cardiovascular disease risk factors with coronary artery calcium volume versus density

Heart ◽  
2017 ◽  
Vol 104 (2) ◽  
pp. 135-143 ◽  
Author(s):  
Isac C Thomas ◽  
Brandon Shiau ◽  
Julie O Denenberg ◽  
Robyn L McClelland ◽  
Philip Greenland ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Artery ◽  
Coronary Artery Calcium ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Density Score ◽  
Volume Score

ObjectivesRecently, the density score of coronary artery calcium (CAC) has been shown to be associated with a lower risk of cardiovascular disease (CVD) events at any level of CAC volume. Whether risk factors for CAC volume and CAC density are similar or distinct is unknown. We sought to evaluate the associations of CVD risk factors with CAC volume and CAC density scores.MethodsBaseline measurements from 6814 participants free of clinical CVD were collected for the Multi-Ethnic Study of Atherosclerosis. Participants with detectable CAC (n=3398) were evaluated for this study. Multivariable linear regression models were used to evaluate independent associations of CVD risk factors with CAC volume and CAC density scores.ResultsWhereas most CVD risk factors were associated with higher CAC volume scores, many risk factors were associated with lower CAC density scores. For example, diabetes was associated with a higher natural logarithm (ln) transformed CAC volume score (standardised β=0.44 (95% CI 0.31 to 0.58) ln-units) but a lower CAC density score (β=−0.07 (−0.12 to −0.02) density units). Chinese, African-American and Hispanic race/ethnicity were each associated with lower ln CAC volume scores (β=−0.62 (−0.83to −0.41), −0.52 (−0.64 to −0.39) and −0.40 (−0.55 to −0.26) ln-units, respectively) and higher CAC density scores (β= 0.41 (0.34 to 0.47), 0.18 (0.12 to 0.23) and 0.21 (0.15 to 0.26) density units, respectively) relative to non-Hispanic White.ConclusionsIn a cohort free of clinical CVD, CVD risk factors are differentially associated with CAC volume and density scores, with many CVD risk factors inversely associated with the CAC density score after controlling for the CAC volume score. These findings suggest complex associations between CVD risk factors and these components of CAC.

Pregnancy-related sacroiliac joint findings in females with low back pain: a four-year magnetic resonance imaging follow-up study

2021 ◽  
pp. 028418512110171
Author(s):  
Rosa Marie Kiil ◽  
Bodil Al-Mashhadi Arnbak ◽  
Anna Zejden ◽  
Berit Schiøttz-Christensen ◽  
Oliver Hendricks ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Low Back Pain ◽  
Back Pain ◽  
Low Back ◽  
Resonance Imaging ◽  
Mri Findings ◽  
Follow Up Study ◽  
Over Time ◽  
Volume Score

Background Pregnancy-related pain may be associated with sacroiliac joint (SIJ) changes, detectable by magnetic resonance imaging (MRI). Purpose To analyze the prevalence and course of SIJ MRI and clinical findings in women referred with low back pain and relate these to pregnancy. Material and Methods A retrospective follow-up study from a longitudinally collected cohort comprising 328 women. Results Women reporting debut of pain in relation to a pregnancy (PP group) tended to have a higher baseline prevalence of all investigated MRI findings, cumulated positive SIJ tests, and a potential fulfilment of the spondyloarthritis diagnosis compared to remainders. The prevalence of subchondral bone marrow edema (BME), any SIJ MRI finding, and potential fulfilment of the spondyloarthritis diagnosis were significantly higher in the PP group compared to women who had not been pregnant. In the total study group, the prevalence of ≥1 MRI finding increased over the four-year study period from 34% to 47% ( P<0.001), driven by increasing prevalence of BME (25% to 32%; P=0.008) and fatty marrow deposition (FMD) (20% to 25%; P=0.020). In addition, the BME volume score increased. Over time, the PP group had persisting high prevalence of buttock pain and total MRI findings and their FMD volume score increased, but there were no between-group differences in MRI variables at follow-up. Conclusion Overall, the prevalence of MRI findings increased over time. Although the PP group had different clinical and SIJ MRI characteristics cross-sectional at baseline compared to remainders, longitudinal analyses revealed that these diminished over time.

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