scholarly journals Brachytherapy seed migration to the lung

2019 ◽  
Author(s):  
Daniel Bell ◽  
Maria Serrado
Keyword(s):  
1986 ◽  
Vol 34 (3) ◽  
pp. 305 ◽  
Author(s):  
BM Potts

Regeneration of a hybrid zone between E. amygdalina and E. risdonii and pure species stands following wildfire is reported, as well as the reproductive and vegetative fitness of parental and hybrid phenotypes. E. risdonii phenotypes dominated the seed rain and seedling cohort and there was clearly a marked fitness differential between E. amygdalina and E. risdonii at their boundary. When the F1 type hybrid is in competition with both parental types it is generally reproductively the least fit, although frequently vegetatively vigorous. Reduced fitness appears to extend to advanced generations as hybrid phenotypes tending.toward either species are, on average, less fit than the corresponding parental type. The pattern of phenotypic fitness suggests that the species' boundary is in disequilibrium and it is argued that E. risdonii is invading the range of E. amygdalina by both pollen and seed migration. There is an asymmetric distribution of F1 type hybrids across the boundary and the hybrid swarm examined is being invaded by E. risdonii genes. It is suggested that hybridization may be associated with natural disequilibrium and, where seed migration is limited, boundary movements may be preceded by a wave of hybridization due partly to pollen swamping of the least fit species. Hybrid swarms may develop but, at the boundary of large stands, are probably transitory. There is a marked inertia in the population response to the prevailing selective regime due to the extremely slow population turnover and limited dispersal potential. This is discussed in the broader context of non-equilibrium models where it is argued that dispersal may be the factor limiting population response to perturbation of a shallow environmental gradient. This is due to large geographical shifts in the position of the null point and would be accentuated in a patchy environment where migration as a front is prevented.


Brachytherapy ◽  
2017 ◽  
Vol 16 (6) ◽  
pp. 1252-1256 ◽  
Author(s):  
Junqing Lin ◽  
Weizhu Yang ◽  
Na Jiang ◽  
Qubin Zheng ◽  
Jingyao Huang ◽  
...  

Author(s):  
W.B Warlick ◽  
D.A Gant ◽  
P.S Albert ◽  
W Sewchand ◽  
M.M Poggi
Keyword(s):  

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Jun Nakashima ◽  
Akitomo Sugawara ◽  
Hirohiko Nagata ◽  
Ryuichi Mizuno ◽  
Naoyuki Shigematsu ◽  
...  

2020 ◽  
Vol 71 (1) ◽  
pp. 58-62
Author(s):  
Klaudia Jumaa ◽  
Badria Al Johani ◽  
Muriel Brackstone ◽  
Anat Kornecki

Objectives: To assess the benefits associated with radioactive seed localization (RSL) in comparison to conventional wire localization (WL) for nonpalpable breast lesions. Methods: Radioactive seed localization was initiated at our institution in July 2013. Retrospective review of all WL performed between June 2012 and July 2013 (2013) and all RSL performed during June 2015 and July 2016 (2016). Patients who received neoadjuvant therapy or did not undergo their planned surgeries and WL performed in 2016 were excluded. The following data were collected: final pathology, resection margins for malignant lesions, time to surgery, seed migration, and number of localized lumpectomies performed by each surgeon. Results: A total of 292 WL procedures (288 women) in 2013 and 194 RSL procedures (186 women) in 2016 were eligible for the study. All WLs were inserted the day of surgery. Mean time from RSL insertion to surgery was 4.0 ± 2.8 days (range: 1-17 days). There was no difference in specimen size for malignant lesions (6.8 ± 2.8 cm for WL and 6.9 ± 2.9 cm for RSL; P = .5). Specimen radiographs were obtained in 233 (80%) of 292 WL compared to 194 (100%) of 194 RSL ( P < .001). For malignant lesions, positive margins were present in 34 (17.2%) of 198 with WL compared to 15 (10.3%) of 146 with RSL ( P < .001). Close margins (≤1 mm) were present in 31 (15.6%) of 198 with WL compared to 1 (0.6%) of 146 with RSL ( P < .001). The seed fell out of the specimen during surgery in 6 (3.1%) of 194. No seed loss was recorded. The surgeons (n = 4) who transitioned to RSL increased the number of surgeries per month from a mean of 4.4 ± 2.6 in 2013 to 6.9 ± 3.5 in 2016, equivalent to a 41% increase ( P = .003). Conclusions: The use of RSL, as compared to conventional WL, resulted in a reduction in the number of pathologically involved surgical margins and was associated with an increased number of surgeries. Furthermore, RSL can be performed up to 14 days prior to surgery, which may improve scheduling flexibility in the radiology department.


Brachytherapy ◽  
2019 ◽  
Vol 18 (3) ◽  
pp. 306-312
Author(s):  
Kenneth W. Merrell ◽  
Brian J. Davis ◽  
Christopher C. Goulet ◽  
Keith M. Furutani ◽  
Lance A. Mynderse ◽  
...  

Brachytherapy ◽  
2009 ◽  
Vol 8 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Akitomo Sugawara ◽  
Jun Nakashima ◽  
Naoyuki Shigematsu ◽  
Etsuo Kunieda ◽  
Atsushi Kubo

2015 ◽  
Vol 115 ◽  
pp. S560-S561 ◽  
Author(s):  
K. Merrell ◽  
B. Davis ◽  
C. Goulet ◽  
K. Furutani ◽  
L. Mynderse ◽  
...  

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