scholarly journals Pulmonary artery stents for stenosis post bilateral lung transplant

2015 ◽  
Author(s):  
Luke Danaher
2021 ◽  
Vol 36 (1) ◽  
pp. 34-41
Author(s):  
Lia Argevani ◽  
Michael J. Schuh ◽  
Sheena Crosby

Objective: To report pharmacogenomics post-related bradykinesia secondary to phenoconversion in an elderly post-bilateral lung transplant patient. Summary: The patient was a 68-year-old double lung transplant patient taking the immunosuppressant and CYP3A4/5 substrate tacrolimus concomitantly with 2 CYP3A4/5 inhibitor medications, fluconazole and diltiazem. This drug combination post-dosing resulted in debilitating bradykinesia 1-2 hours after dosing, increasing the risk of falls and possible increased mortality and morbidity risk. Conclusion: Taking tacrolimus in combination with CYP3A4/5 inhibitors may increase neurologic adverse effects resulting in increased fall and associated increased mortality and morbidity risk.


2019 ◽  
Vol 23 ◽  
pp. 77-80 ◽  
Author(s):  
Laila S. Al Yazidi ◽  
Julie Huynh ◽  
Philip N. Britton ◽  
C. Orla Morrissey ◽  
Tony Lai ◽  
...  

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