scholarly journals Effect of a program of institutional physical activity on oxidative stress in the elderly with and without metabolic syndrome / Efecto de un programa de actividad física institucional sobre el estrés oxidativo en el adulto mayor con y sin síndrome metaból

2015 ◽  
Vol 15 (8) ◽  
Author(s):  
Hector Daniel Hernandez
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Metabolic Syndrome ◽  
The Elderly ◽  
Estrés Oxidativo

Differences in physical function and metabolic syndrome risk factors according to the level of physical activity in elderly Korean men: a pilot study

2020 ◽  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Physical Function ◽  
Vigorous Physical Activity ◽  
Density Lipoprotein ◽  
The Elderly ◽  
Berg Balance Scale ◽  
Lower Percentage ◽  
Mineral Density

Background and objective: Managing the decrease in physical function in the elderly is a major task in aging societies globally. Here, we aimed to compare the physical function and metabolic syndrome (MetS) risk factors according to levels of physical activity (PA). Material and methods: We measured PA in 77 elderly Korean men (74.21 ± 6.26 years old) with an accelerometer and recorded body composition, physical function, and MetS-related risk factors. Participants were divided into three groups based on daily moderate-vigorous physical activity (MVPA): low (under 60 min), middle (60-120 min), and high (over 120 min). The groups were compared using a one-way analysis of variance and the Scheffe post hoc test. Odds ratios (OR) were calculated by logistic regression analysis. Results: Significant differences were found between the groups for sedentary behavior time (P < 0.001), light PA (P < 0.05), moderate PA (P < 0.001), vigorous PA (P < 0.05), and total energy expenditure (P < 0.001). The high PA group showed a significantly lower percentage of body fat and fat mass and higher muscle mass than did the low and middle PA groups (P < 0.05). The 6-min walk test was significantly better in the high PA group than in the low and middle PA groups (P < 0.05). Grip strength and the Berg balance scale were also significantly better in the high PA group (P < 0.05). Bone mineral density (BMD) and high-density lipoprotein cholesterol (HDL-C) were significantly higher in the high PA group than in the low PA group (P < 0.05). Systolic blood pressure (SBP) was significantly higher in the middle PA group than in the low PA group (P < 0.05). Participants with more than three MetS criteria showed an OR of 0.09 (95% confidence interval 0.01-0.82) in the high PA group as compared with the low PA group (P < 0.05). Conclusions: Moderate-vigorous physical activity of more than 120 min daily showed better physical function and lower OR of MetS than did lower MVPA levels in elderly Korean men.

scholarly journals Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Antoine Raberin ◽  
Philippe Connes ◽  
Jean-Claude Barthélémy ◽  
Pia Robert ◽  
Sébastien Celle ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Diseases ◽  
Cardiovascular Risk Factors ◽  
The Elderly ◽  
Activity Level ◽  
Advanced Oxidation Protein Products ◽  
The Impact

Background. Cardiovascular diseases remain as the leading cause of morbidity and mortality in industrialized countries. Ageing and gender strongly modulate the risk to develop cardiovascular diseases but very few studies have investigated the impact of gender on cardiovascular diseases in the elderly, which represents a growing population. The purpose of this study was to test the impact of gender and physical activity level on several biochemical and clinical markers of cardiovascular risk in elderly individuals. Methods. Elderly individuals (318 women (75.8±1.2 years-old) and 227 men (75.8±1.1 years-old)) were recruited. Physical activity was measured by a questionnaire. Metabolic syndrome was defined using the National Cholesterol Education Program Expert Panel’s definition. Polysomnography and digital tonometry were used to detect obstructive sleep apnea and assess vascular reactivity, respectively. Blood was sampled to measure several oxidative stress markers and adhesion molecules. Results. The frequency of cardiovascular diseases was significantly higher in men (16.4%) than in women (6.1%) (p<0.001). Body mass index (25.0±4.3 vs. 25.8±3.13 kg.m−2) and glycaemia (94.9±16.5 vs. 101.5±22.6 mg.dL−1) were lower, and High Density Lipoprotein (HDL) (74.6±17.8 vs. 65.0±17.2 mg.dL−1) was higher in women compared to men (p<0.05). Oxidative stress was lower in women than in men (uric acid: 52.05±13.78 vs. 59.84±13.58, advanced oxidation protein products: 223±94 vs. 246±101 μmol.L−1, malondialdehyde: 22.44±6.81 vs. 23.88±9.74 nmol.L−1). Physical activity was not associated with lower cardiovascular risk factors in both genders. Multivariate analyses showed an independent effect of gender on acid uric (β=0.182; p=0.020), advanced oxidation protein products (β=0.257; p<0.001), and HDL concentration (β=−0.182; p=0.026). Conclusion. These findings suggest that biochemical cardiovascular risk factors are lower in women than men which could explain the lower cardiovascular disease proportion observed in women in the elderly.

scholarly journals Prevalence and correlates of metabolic syndrome and its components in nearly 10 million participants of northwestern China: a cross-sectional study

2020 ◽  
Author(s):  
yinxia su ◽  
Wenli Li ◽  
Yaoqin Lu ◽  
Mingyue Xue ◽  
Muyaseer Haireti ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Ethnic Groups ◽  
Central Obesity ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Chinese Adults ◽  
Cross Sectional ◽  
Low Hdl

Abstract Background The prevalence of metabolic syndrome (MetS) of comprehensive population are always lower than mono- population. However, studies on MetS and its components of it and its subgroups (different ages, genders, races, regions) based on big data and using a same diagnosis criterion are rare. Method: A total of 9,745,640 Chinese adults aged ≥ 18 years in Xinjiang,the largest autonomous region of Multi-ethnic, were enrolled in the study. MetS was defined by modified Adults Treatment Panel (ATP III) criteria.Prevalence of metabolic syndrome and its components were calculated. To further explore the correlates of MetS and its components logistic regression were used. Results The overall prevalence of MetS was 20.85% [Sex: 20.06% in female, 21.56% in man; Age: 39.22% in 60 year older followed by 40–59 year 26.32% and 18–39 years 9.56%; Ethnicity: 28.19% in Hui followed by Han (26.39%), Uyghur(18.56%), Other(18.61%), Kazak(17.98%), Mongolian (17.87%), Kyrgyz(14.44%)], living in city and town (23.03%) or north(24.78%) had higher prevalence of MetS than living in rural (19.94%) and South (17.66%). Although the prevalence of hypertension, smoking, drinking and lack of physical activity in Kyrgyz, Mongolian and Kazakh were higher than those of other ethnic groups, the risk of MetS was lower than that of other. The results also showed that although their risk of central obesity and hypertension was higher than that of Han, Hui, Uygur and other, the risk of high-TG, low HDL-C and Elevated-FPG was significantly lower than that of other ethnic groups. Among them, the Mongolian had the lowest risk of high-TG and low-HDL-C, while the Kazakh had the lowest risk of elevated-FPG. In addition, except that the risk of central obesity in males was lower than that in females, the other components of males were higher than those in females, but the risk of MetS was lower than that in females. The risk of MetS and its components in the elderly was significantly higher than that in the young, and physical activity did not show reduce the risk of MetS in the general population. Conclusion The reason why the prevalence of MetS in the comprehensive population is lower than that in most mono-population may be that some subgroups of the population have the ability to resist risk factors in terms of genetic structure such as Kyrgyz, Mongolian, Kazak, and the influence in this aspect may exceed that of lifestyle. Within each subgroup, the prevalence of MetS is still increasing. Central obesity is an important risk factor for women with MetS. Elevated-FPG and high-TG are the most important risk factors of MetS in Han, Hui. Climate and lifestyle are the main causes of MetS in northern Xinjiang and city and town residents.

scholarly journals PENYULUHAN AKTIVITAS FISIK DAN SCREENING PARAMETER SINDROM METABOLIK PADA POPULASI LANSIA

MEDIKORA ◽  
2019 ◽  
Vol 18 (1) ◽  
pp. 33-39
Author(s):  
Cerika Rismayanthi ◽  
Prijo Sudibjo ◽  
Novita Intan Arovah ◽  
Krisnanda Dwi Apriyanto
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Physical Fitness ◽  
The Elderly ◽  
Health Check ◽  
Elderly Men ◽  
Fitness Level ◽  
Health Checks ◽  
The Metabolic Syndrome ◽  
Screening Parameter

Kegiatan Program Pengabdian kepada Masyarakat ini bertujuan untuk: (1) mendapatkan informasi tentang profil tingkat kebugaran lansia binaan Ikatan Dokter Indonesia (IDI) dan Ikatan Istri Dokter Indonesia (IIDI) Yogyakarta, (2) mendapatkan informasi tentang faktor risiko sindrom metabolik bagi lansia binaan Ikatan Dokter Indonesia (IDI) dan Ikatan Istri Dokter Indonesia (IIDI) Yogyakarta, (3) memberikan pengetahuan bagi lansia binaan Ikatan Dokter Indonesia (IDI) dan Ikatan Istri Dokter Indonesia (IIDI) Yogyakarta tentang pentingnya melakukan aktivitas fisik dan mengetahui parameter sindrom metabolik. Khalayak sasaran utama dari kegiatan ini adalah Kelompok Lansia Teratai Nogotirto, Kelurahan Nogotirto, Kecamatan Gamping Sleman berjumlah 118 orang. Metode kegiatan PPM dilakukan dengan beberapa kegiata meliputi: cek kesehatan, tes pengukuran kebugaran jasmani bagi lansia, serta evaluasi dan penyuluhan. Cek kesehatan meliputi pengukuran tekanan darah, lingkar perut, trigliserida, HDL dan glukosa darah puasa. Penyuluhan diberikan setelah para lansia mendapatkan hasil dari cek kesehatan. Metode penyuluhan dilakukan agar para lansia mempunyai motivasi untuk menjaga kesehatan dan terhindar dari sindrom metabolik yang dapat memicu munculnya penyakit degeneratif. Tes pengukuran kebugaran jasmani meliputi jalan selama 6 menit, fleksibilitas, keseimbangan. Pengisian kuesioner dilakukan untuk mengetahui seberapa penting manfaat kegiatan PPM ini bagi para lansia. Berdasarkan hasil cek kesehatan diperoleh data bahwa sejumlah 78 (66,1%) lansia terindikasi sindrom metabolik. Dan dari sejumlah 78 lansia, 98,71% (77 lansia) yang terindikasi sindrom metabolik adalah perempuan. Dari data lansia laki-laki diperoleh rata-rata usia 61,5 tahun, dengan norma normal jalan 6 menit lansia laki-laki dengan usia tersebut adalah 610 – 735 yards (558-672 meter) dan norma normal jalan 6 menit lansia wanita dengan usia tersebut adalah 545 – 660 yards (498-603 meter). Jadi kesimpulan dari tes kebugaran lansia, baik laki-laki maupun wanita mempunyai tingkat kebugaran yang di atas rata-rata (above average). Physical Activity Counseling and Screening Parameter Metabolic Syndrome in the Elderly PopulationAbstractThe Community Service Program activity aims to: (1) obtain information on the profile of the fitness level of the elderly under the guidance of the Indonesian Doctors Association (IDI) and the Indonesian Doctors' Wives Association (IIDI) Yogyakarta, (2) obtain information about the risk factors for metabolic syndrome for the elderly under the guidance of the Association Indonesian Doctors (IDI) and the Indonesian Doctors 'Wives Association (IIDI) Yogyakarta, (3) provides knowledge for the elderly assisted by the Indonesian Doctors Association (IDI) and the Indonesian Doctors' Wives Association (IIDI) Yogyakarta about the importance of physical activity and knowing the parameters of metabolic syndrome. The main target audience for this activity is the Elderly Lotus Group Nogotirto, Kelurahan Nogotirto, Sleman Gamping District, with a total of 118 people. The PPM activity method is carried out with several activities including: health check, physical fitness measurement test for the elderly, as well as evaluation and counseling. Health checks include measurements of blood pressure, stomach circumference, triglycerides, HDL and fasting blood glucose. Counseling is given after the elderly get the results of a health check. The counseling method is done so that the elderly have motivation to maintain health and avoid the metabolic syndrome which can trigger the emergence of degenerative diseases. Physical fitness measurement tests include walking for 6 minutes, flexibility, balance. The questionnaire was filled out to find out how important the benefits of PPM activities are for the elderly. Based on the results of health checks obtained data that a number of 78 (66.1%) elderly indicated metabolic syndrome. And of the 78 elderly, 98.71% (77 elderly) who indicated metabolic syndrome were women. From the data of elderly men obtained an average age of 61.5 years, with the normal norm of walking 6 minutes elderly men with that age is 610 - 735 meters (558-672 meters) and the normal norm of walking 6 minutes elderly women with age these are 545 - 660 yards (498-603 meters). So the conclusion of the elderly fitness test, both men and women have a fitness level that is above average (above average).

Effect of Intensive Physical Activity on Oxidative Stress in Elderly People with Metabolic Syndrome

2010 ◽  
Vol 49 ◽  
pp. S40-S41
Author(s):  
Raquel Retana-Ugalde ◽  
Taide L. Arista-Ugalde ◽  
Víctor Manuel Mendoza-Núñez
Keyword(s):  
Oxidative Stress ◽  
Physical Activity ◽  
Metabolic Syndrome ◽  
Elderly People

scholarly journals Oxidative Stress and Metabolic Syndrome: Cause or Consequence of Alzheimer's Disease?

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Diana Luque-Contreras ◽  
Karla Carvajal ◽  
Danira Toral-Rios ◽  
Diana Franco-Bocanegra ◽  
Victoria Campos-Peña
Keyword(s):  
Oxidative Stress ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Metabolic Syndrome ◽  
Neuronal Damage ◽  
Critical Role ◽  
Neurofibrillary Tangle ◽  
The Elderly ◽  
Amyloid A ◽  
New Therapeutic Approaches

Alzheimer’s disease (AD) is a major neurodegenerative disease affecting the elderly. Clinically, it is characterized by a progressive loss of memory and cognitive function. Neuropathologically, it is characterized by the presence of extracellularβ-amyloid (Aβ) deposited as neuritic plaques (NP) and neurofibrillary tangles (NFT) made of abnormal and hyperphosphorylated tau protein. These lesions are capable of generating the neuronal damage that leads to cell death and cognitive failure through the generation of reactive oxygen species (ROS). Evidence indicates the critical role of Aβmetabolism in prompting the oxidative stress observed in AD patients. However, it has also been proposed that oxidative damage precedes the onset of clinical and pathological AD symptoms, including amyloid-βdeposition, neurofibrillary tangle formation, vascular malfunction, metabolic syndrome, and cognitive decline. This paper provides a brief description of the three main proteins associated with the development of the disease (Aβ, tau, and ApoE) and describes their role in the generation of oxidative stress. Finally, we describe the mitochondrial alterations that are generated by Aβand examine the relationship of vascular damage which is a potential prognostic tool of metabolic syndrome. In addition, new therapeutic approaches targeting ROS sources and metabolic support were reported.

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