scholarly journals Validation of Whole Blood Rapid Diagnosis Test for Hepatitis B

2020 ◽  
Vol 86 (1) ◽  
Author(s):  
Jose D. Debes ◽  
Gertine van Oord ◽  
Andre Boonstra
2014 ◽  
Vol 52 (01) ◽  
Author(s):  
W Dammermann ◽  
EM Stiel ◽  
M Kohring ◽  
J Schulze zur Wiesch ◽  
AW Lohse ◽  
...  

2019 ◽  
Vol 11 (4) ◽  
pp. 314-315
Author(s):  
James S Leathers ◽  
Maria Belen Pisano ◽  
Viviana Re ◽  
Gertine van Oord ◽  
Amir Sultan ◽  
...  

Abstract Background Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradication worldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usually constrained by testing costs. Methods We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141 individuals. Results The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotype or viral load (in samples with such information, 90%). Conclusions The HCV test validated in this study can allow for HCV screening in areas of need when properly used.


2012 ◽  
Vol 11 (1) ◽  
Author(s):  
Hypolite Mavoko Muhindo ◽  
Gillon Ilombe ◽  
Ruth Meya ◽  
Patrick M Mitashi ◽  
Albert Kutekemeni ◽  
...  

OALib ◽  
2020 ◽  
Vol 07 (10) ◽  
pp. 1-7
Author(s):  
Berry Ikolango Bongenya ◽  
Ben Ilunga Bulanda ◽  
Erick Ntambwe Kamangu

1997 ◽  
Vol 43 (9) ◽  
pp. 1764-1770 ◽  
Author(s):  
Michael J Benecky ◽  
Diane R Post ◽  
Susan M Schmitt ◽  
Manish S Kochar

Abstract Coupled particlelight scattering (Copalis™) is a homogeneous immunoassay technology that permits simultaneous determination of multiple analytes in serum, plasma, or whole blood. Copalis differentiates monomeric latex microparticles from latex aggregates and cells on the basis of their unique light scatter properties. Copalis readily discriminates small (∼0.1 μm) differences in latex microparticle size. Therefore, multiple simultaneous assays are configured by the use of mixtures of different-size latex microparticles. The Copalis research immunoassay for hepatitis B surface antigen (HBsAg) is configured in a sandwich format where the extent of light scatter histogram broadening due to HBsAg-mediated binding of colloidal gold to latex provides the basis for antigen quantification. Simultaneous Copalis forward- and wide-angle light scatter measurements allow discrimination of latex microparticles from the cell components of whole blood. Consequently, direct detection of HBsAg in unprocessed whole-blood samples by Copalis is feasible.


2014 ◽  
Vol 17 ◽  
pp. 19619 ◽  
Author(s):  
Eleni Kakalou ◽  
Vasileios Papastamopoulos ◽  
Panagiotis Ioannidis ◽  
Kostas Papanikolaou ◽  
Ourania Georgiou ◽  
...  

2009 ◽  
Vol 24 (10) ◽  
pp. 3120-3125 ◽  
Author(s):  
Hun Joo Lee ◽  
Kak Namkoong ◽  
Eun Chol Cho ◽  
Christopher Ko ◽  
Jae Chan Park ◽  
...  

2015 ◽  
Vol 60 (6) ◽  
pp. 892-899 ◽  
Author(s):  
Eleftherios Mylonakis ◽  
Cornelius J. Clancy ◽  
Luis Ostrosky-Zeichner ◽  
Kevin W. Garey ◽  
George J. Alangaden ◽  
...  

2018 ◽  
Vol 42 (2) ◽  
Author(s):  
Sema Ertug ◽  
◽  
Sercin Ozlem Caliskan ◽  
Erdogan Malatyali ◽  
Hatice Ertabaklar ◽  
...  

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