Bilateral Stifle Osteochondritis Dissecans in a Cat

2005 ◽  
Vol 41 (1) ◽  
pp. 78-80 ◽  
Author(s):  
S. Christopher Ralphs

A 9-month-old, castrated male, domestic shorthaired cat was presented for progressive right hind-limb lameness. A diagnosis of osteochondritis dissecans of the lateral femoral condyle was made based on radiographs and physical examination, and was confirmed by right lateral stifle arthrotomy. The cartilage flap was removed, and the underlying bone was curetted. Seven months later, the cat was sound on the right leg but developed a left hind-limb lameness. A similar lesion was found in the left leg and was treated identically. Fourteen months after presentation, the cat was sound on both hind limbs.

2014 ◽  
Vol 40 (04) ◽  
pp. 209-214
Author(s):  
Wan-Wen Huang ◽  
Chih-Chueh Jen ◽  
Wei-Ming Lee

A 14-year-old intact male Chinchilla cat was presented to Veterinary Teaching Hospital, Chung Hsing University due to a sudden weakness of the hind limbs. Coldness was found on both hind limbs. Pulseless on the right hind limb and a weak-pulsed on the left hind limb were revealed by physical examination. Thrombus was detected in aortic bifurcation by ultrasonography. After treating the patient with supportive care, antithrombotics (including Dalteparin sodium, clopidgrel) and thrombolytics (Streptokinase), the thrombus lysed on the next day. Being able to use the affected limbs in the following days, the cat was discharged on the 6th day, although Ischemia-reperfusion injury was still presented. It indicated that thrombolytics may be a choice that is beneficial to some cats with distal aortic thromboembolism.


2000 ◽  
Vol 49 (1) ◽  
pp. 9-14
Author(s):  
Takahiro Kitamura ◽  
Masahiro Kina ◽  
Kenji Goto ◽  
Takenori Akiyama ◽  
Hideya Kawamura

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Davoud Kazemi ◽  
Ashraf Fakhrjou ◽  
Vahid Mirzazadeh Dizaji ◽  
Majid Khanzadeh Alishahi

The effect of autologous platelet rich fibrin (PRF), a second generation platelet product, on the healing of experimental articular cartilage lesions was evaluated in an animal model. Full thickness cartilage lesions with a diameter of 6 mm and depth of 5 mm were created in the weight bearing area of femoral condyles of both hind limbs in 12 adult mixed breed dogs. Defects in the left hind limb of each dog were repaired by PRF implantation whereas those in the right hind limb were left empty. The animals were euthanized at 4, 16, and 24 weeks following surgery and the resultant repair tissue was investigated macroscopically and microscopically. The results of macroscopic and histological evaluations indicated that there were significant differences between the PRF treated and untreated defects. In conclusion, the present study indicated that the use of platelet rich fibrin as a source of autologous growth factors leads to improvement in articular cartilage repair.


2021 ◽  
Vol 9 (8) ◽  
pp. 232596712110269
Author(s):  
Liang Zhou ◽  
Shawn M. Gee ◽  
Philip L. Wilson ◽  
Sharon Huang ◽  
K. John Wagner ◽  
...  

Background: Repetitive microtrauma may contribute to osteochondritis dissecans (OCD) lesions of the femoral condyle. The effect of differential loading between OCD weightbearing (WB) zones has not been studied. Purpose: To determine whether clinical and radiographic variables differ by WB zone in lateral femoral condyle OCD lesions. Study Design: Cohort study; Level of evidence, 3. Methods: We retrospectively reviewed a consecutive series of patients aged <18 years with lateral femoral condyle OCD lesions presenting at a single institution between 2004 and 2018. Patients with OCD lesions outside of the lateral femoral condyle were excluded. Lesions were localized on radiographs using the Cahill and Berg classification, referencing the Blumensaat line and an extension of the posterior femoral cortex. Progeny bone characteristics evaluated at baseline and 24-month follow-up included ossification, distinct borders from parent bone, and displacement. Baseline lesion dimensions were measured on magnetic resonance imaging (MRI) scans. We evaluated posttreatment pain level, return-to-activity rate, and patient-reported outcome measures (PROMs) including the Pediatric International Knee Documentation Committee score, Knee injury and Osteoarthritis Outcome Score, and Pediatric Functional Activity Brief Scale. Results: A total of 62 lateral femoral condyle OCD lesions (mean follow-up, 24.1 months) presented within the study period: 26 WB lesions and 36 nonweightbearing (NWB) lesions. At presentation, no differences between the lesion types were observed in symptom chronicity or symptomatology. NWB lesions were deeper on MRI scans (sagittal depth, 7.11 vs 5.96 mm; P = .046; coronal depth ratio, 0.05 vs 0.01 mm; P = .003), were more likely to develop progeny bone (69.4% vs 44%; P = .047), and demonstrated higher radiographic healing rates (52.8% vs 24%; P = .025) compared with WB lesions. PROMs at follow-up were available for 25 of 62 patients (40.3%), with no statistically significant differences between cohorts at any time. Return to full activity was observed in 72% of WB and 82.1% of NWB lesions ( P = .378). Conclusion: Lateral femoral condyle OCD lesions of the knee in WB and NWB zones presented similarly at initial evaluation; however, NWB lesions demonstrated higher rates of progeny bone formation and radiographic healing at mean 2-year follow-up.


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