scholarly journals Interventional pain therapy in cervical post-surgery syndrome

2016 ◽  
Vol 5 (2) ◽  
pp. 38
Author(s):  
Stephan Klessinger
2000 ◽  
Vol 18 (7) ◽  
pp. 1598-1600 ◽  
Author(s):  
David P. Seamans ◽  
Gilbert Y. Wong ◽  
Jack L. Wilson

2006 ◽  
Vol 10 (S1) ◽  
pp. S146-S146
Author(s):  
M. Escher ◽  
A. Cahana ◽  
L. Robert ◽  
S. Pautex

2010 ◽  
Vol 3;13 (3;5) ◽  
pp. 263-271
Author(s):  
Christof Birkenmaier

Background: Radiofrequency (RF) and cryolesioning are established methods for the therapeutic interruption of sensory nerve supply to facet joints and other painful musculoskeletal structures. The varying clinical success rates of these treatments have – among other technical issues – been attributed to the small size of these lesions combined with the limited precision in placing them. Since there are 2 different physical methods for lesioning and a wide range of probes and lesion generators available, it is likely that the lesions generated by them may be of different size. Objectives: We sought to devise an experimental setup that would allow for the reproducible and comparable evaluation of the size of cryo and RF lesions as they are being used in interventional pain therapy. Methods: A wide range of potential media was evaluated for this purpose. Based on technical specifications, as well as on preliminary testing, a specific agar agar gel with a gel point of between 32o C and 35o C and a melting point of between 80o C and 85o C was selected for these experiments. Two different testing containers were constructed from transparent acrylic: one with a volume of 1,500 mL and the other with a volume of 12 mL. Each of them allows for the introduction of a cryo or a RF probe and 2 bundles of thermoelements into the gel volume. A water bath was used to maintain the gels at 37o C and bundled, ultrafine NiCr-Ni thermoelements type K were used for measuring the isotherms. A series of RF and cryolesions were performed within these experimental setups to evaluate their suitability for the comparative testing of cryo and RF probes and generators. Results: Both testing setups generated reproducible results and proved to be suitable for measuring RF as well as cryolesions. Visual observation of the lesions was better with the small testing container and rewarming / recooling after performing a cryo / RF lesion was more rapid with the smaller gel volume. Limitations: Our setup allows for the comparative measurement of RF and cryolesions, but it cannot simulate the realities within living tissue. While convection as a confounding factor was excluded by use of a gel, capillary perfusion and the specific characteristics of different tissues cannot be simulated. Conclusions: The testing setup described in this manuscript can serve for the comparative and reproducible study of RF and cryolesions that are commonly used in interventional pain therapy. Key words: Radiofrequency lesioning, cryolesioning, interventional pain therapy, experimental study, agar agar gel, thermoelement.


2004 ◽  
Vol 100 (4) ◽  
pp. 1019-1021 ◽  
Author(s):  
Sara Haspeslagh ◽  
Jan Van Zundert ◽  
Martine Puylaert ◽  
Rene Heylen ◽  
Maarten van Kleef ◽  
...  

Author(s):  
S. I. Coleman ◽  
W. J. Dougherty

In the cellular secretion theory of mineral deposition, extracellular matrix vesicles are believed to play an integral role in hard tissue mineralization (1). Membrane limited matrix vesicles arise from the plasma membrane of epiphyseal chondrocytes and tooth odontoblasts by a budding process (2, 3). Nutritional and hormonal factors have been postulated to play essential roles in mineral deposition and apparently have a direct effect on matrix vesicles of calcifying cartilage as concluded by Anderson and Sajdera (4). Immature (75-85 gm) Long-Evans hooded rats were hypophysectomized by the parapharyngeal approach and maintained fourteen (14) days post-surgery. At this time, the animals were anesthetized and perfusion fixed in cacodylate buffered 2.5% glutaraldehyde. The proximal tibias were quickly dissected out and split sagittally. One half was used for light microscopy (LM) and the other for electron microscopy (EM). The halves used for EM were cut into blocks approximately 1×3 mm. The tissue blocks were prepared for ultra-thin sectioning and transmission EM. The tissue was oriented so as to section through the epiphyseal growth plate from the zone of proliferating cartilage on down through the hypertrophic zone and into the initial trabecular bone. Sections were studied stained (double heavy metal) and unstained.


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