Bladder Cancer Diagnosis: The Role of CT Urography

2015 ◽  
Vol 101 (4) ◽  
pp. 412-417 ◽  
Author(s):  
Emanuela Capalbo ◽  
Anna Kluzer ◽  
Michela Peli ◽  
Maria Cosentino ◽  
Elisabetta Berti ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Diagnosis ◽  
Ct Urography

Bladder cancer diagnosis with CT urography: test characteristics and reasons for false-positive and false-negative results

2017 ◽  
Vol 43 (3) ◽  
pp. 663-671 ◽  
Author(s):  
Tony W. Trinh ◽  
Daniel I. Glazer ◽  
Cheryl A. Sadow ◽  
V. Anik Sahni ◽  
Nina L. Geller ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Diagnosis ◽  
False Positive ◽  
False Negative ◽  
Ct Urography ◽  
Test Characteristics ◽  
Negative Results ◽  
False Negative Results

scholarly journals Evaluation of Serum miR-17-92 Cluster as Noninvasive Biomarkers for Bladder Cancer Diagnosis

2021 ◽  
Vol 11 ◽  
Author(s):  
Jingyao Wang ◽  
Xiqi Peng ◽  
Rongkang Li ◽  
Kaihao Liu ◽  
Chunduo Zhang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Diagnosis ◽  
Clinical Stage ◽  
Diagnostic Model ◽  
Qrt Pcr ◽  
Noninvasive Biomarker ◽  
Noninvasive Biomarkers ◽  
Cancer Tissues ◽  
Geo Database

Previous studies have shown that the miR-17-92 cluster is involved in the occurrence and development of bladder cancer. However, the role of serum miR-17-92 cluster in the diagnosis of bladder cancer has not been studied. In the present study, we evaluated the expression of miR-17-92 cluster members in bladder cancer tissues by analyzing 428 cases from TCGA database. Next, we collected the sera of 74 bladder cancer patients and 90 controls, and used qRT-PCR to detect the relative expression of the cluster. The results showed that the expression of the cluster members in the sera of patients were significantly higher than that of the controls, and they were positively correlated with the clinical stage and pathological grade of the patients. We evaluated their ability to diagnose bladder cancer using ROC, of which miR-92a-3p (AUC = 0.902), miR-17-5p (AUC = 0.845) and miR-20a-5p (AUC = 0.806) were the most prominent. Finally, we established a diagnostic model by logistic regression (AUC = 0.969). We further validated the results of the study using another dataset from the GEO database. Moreover, we evaluated the prognostic value of the cluster. The results revealed that miR-20a-5p was correlated with recurrence of bladder cancer. In summary, the present study validated the overexpression of serum miR-17-92 cluster in bladder cancer. The model composed of the three cluster members were confirmed to be a promising noninvasive biomarker for bladder cancer diagnosis.

Methods for bladder cancer diagnosis – The role of autofluorescence and photodynamic diagnosis

2019 ◽  
Vol 27 ◽  
pp. 141-148 ◽  
Author(s):  
Kamil Bochenek ◽  
David Aebisher ◽  
Anna Międzybrodzka ◽  
Grzegorz Cieślar ◽  
Aleksandra Kawczyk-Krupka
Keyword(s):  
Bladder Cancer ◽  
Cancer Diagnosis ◽  
Photodynamic Diagnosis

792: Role of Oxidative Stress in Tumorigenic Potential of Bladder Cancer Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 214-215 ◽  
Author(s):  
Daniel Cho ◽  
Xiao Fang Ha ◽  
J. Andre Melendez ◽  
Louis J. Giorgi ◽  
Badar M. Mian
Keyword(s):  
Oxidative Stress ◽  
Bladder Cancer ◽  
Cancer Cells ◽  
Tumorigenic Potential ◽  
Bladder Cancer Cells
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