Synthesis, characterization of dextran hydrogels and their in vitro release of gentamycin sulphate

2015 ◽  
Vol 13 (3) ◽  
pp. 0-0 ◽  
Author(s):  
Rui Guo ◽  
Peizhe Chen ◽  
Yunfei Mo ◽  
Yong Lan ◽  
Wei Xue ◽  
...  
Keyword(s):  
In Vitro Release ◽  
Vitro Release

Preparation and characterization of fentanyl-loaded PLGA microspheres: in vitro release profiles

2002 ◽  
Vol 234 (1-2) ◽  
pp. 195-203 ◽  
Author(s):  
Hak Soo Choi ◽  
Sun-Ah Seo ◽  
Gilson Khang ◽  
John M. Rhee ◽  
Hai Bang Lee
Keyword(s):  
In Vitro Release ◽  
Plga Microspheres ◽  
Vitro Release ◽  
Release Profiles

scholarly journals Development and Characterization of Hemicellulose-Based Films for Antibacterial Wound-Dressing Application

Polymers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 548 ◽  
Author(s):  
Naveed Ahmad ◽  
Danial Tayyeb ◽  
Imran Ali ◽  
Nabil K. Alruwaili ◽  
Waqas Ahmad ◽  
...  
Keyword(s):  
Wound Dressing ◽  
Transmission Rate ◽  
In Vitro Release ◽  
Antibacterial Activities ◽  
Cell Viability Assay ◽  
Viability Assay ◽  
Psyllium Husk ◽  
Vitro Release

Hemicelluloses are biopolymers with versatile properties for biomedical applications. Herein, hemicellulose (arabinoxylan)-based antibacterial film dressings were prepared and characterized. Arabinoxylan was isolated from psyllium husk. Blank and gentamicin-loaded films were prepared by the solvent cast method using glycerol as the plasticizer. The appropriate composition of the films was obtained by varying the amounts of arabinoxylan, glycerol, and gentamicin. The films were found to be transparent, smooth, bubble-free, flexible, and easily peelable with 2% to 3% arabinoxylan. They had uniform thickness and swelled up to 60% of their initial size. The mechanical properties and water vapor transmission rate through the films were found to be suitable for wound-dressing application. Fourier transform infrared spectroscopy (FTIR) analysis confirmed drug–film compatibility. In an in vitro release study, more than 85% of the gentamicin was released from the films in 12 h. The antibacterial activities of the gentamicin-loaded films were found to be close to the standard gentamicin solution. The films were found to be cytocompatible in cell viability assay. These results suggested that hemicellulose-based films are promising materials for the dressing of infected wounds.

scholarly journals Development and characterization of PLGA nanocapsules of grandisin isolated from Virola surinamensis: in vitro release and cytotoxicity studies

2013 ◽  
Vol 23 (1) ◽  
pp. 153-159 ◽  
Author(s):  
Luciano Aparecido Stecanella ◽  
Stephânia Fleury Taveira ◽  
Ricardo Neves Marreto ◽  
Marize C. Valadares ◽  
Marcelo de Sousa Vieira ◽  
...  
Keyword(s):  
In Vitro Release ◽  
Cytotoxicity Studies ◽  
Vitro Release

Formulation and characterization of curcumin-loaded microemulsions: evaluation of antioxidant stability and in vitro release

2021 ◽  
pp. 116881
Author(s):  
Aibibai Amuti ◽  
Xue Wang ◽  
Mingyang Zan ◽  
Shaojun Lv ◽  
Zhanzhong Wang
Keyword(s):  
In Vitro Release ◽  
Vitro Release

In vitro release of somatostatin from cerebral cortical slices: characterization of electrically evoked release

1988 ◽  
Vol 447 (1) ◽  
pp. 92-97 ◽  
Author(s):  
Giambattista Bonanno ◽  
Maurizio Raiteri ◽  
Piers C. Emson
Keyword(s):  
In Vitro Release ◽  
Vitro Release ◽  
Cortical Slices

scholarly journals Preparation and Characterization of Etodolac as a Topical Nanosponges Hydrogel

2019 ◽  
Vol 28 (1) ◽  
pp. 64-74
Author(s):  
Maysam M. Abass ◽  
Nawal A. Rajab
Keyword(s):  
Particle Size ◽  
In Vitro Release ◽  
Diffusion Method ◽  
Internal Phase ◽  
Stirring Time ◽  
Vitro Release ◽  
Emulsion Solvent Diffusion Method ◽  
Polymer Ratio

Nanosponges (NS) of etodolac(ETO) was prepared using the emulsion solvent diffusion method ; the effects of drug: polymer ratio, the effect of level concentration of internal phase and stirring time and other variables that effect on the physical characteristics of NS were investigated and characterized, The selected formula was lyophilized then incorporated into hydrogel ; which also evaluated .The results show that the formulation that contain Drug: PVA:EC in ratio 1:3:2 is the best with smallest particle size 40.2±0.098 with polydispersibility0.005 and in vitro release 97.6±0.11%, , ETO NS Carbopol hydrogel produced a significant(p<0.05) improvement of the in vitro release than pure ETO hydrogel.

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