Efficacy of Bone Source ™ and Cementek ™ in Comparison with Endobon ™ in Critical Size Metaphyseal Defects, Using a Minipig Model

2010 ◽  
Vol 8 (3) ◽  
pp. 175-185 ◽  
Author(s):  
Christian K.G. Spies ◽  
Stefan Schnürer ◽  
Tobias Gotterbarm ◽  
Steffen J. Breusch
Keyword(s):  
Critical Size

Public and Private Net Savings in Developing Countries: Some Empirical Tests for the Period 1972-88 (Distinguishedl Lecture)

1992 ◽  
Vol 31 (4I) ◽  
pp. 431-447
Author(s):  
Peter A. Cornelisse ◽  
Elma Van De Mortel
Keyword(s):  
Public Debt ◽  
World Economy ◽  
Socioeconomic Development ◽  
Critical Size ◽  
Public And Private ◽  
Critical Dimensions ◽  
The Public ◽  
Empirical Tests ◽  
Financial Issues

The severe shocks that rocked the world economy in the 1970s and the ensuing efforts to adjust and to renew economic growth have had a profound effect on the economic literature. Especially the external and public debt problems which reached critical dimensions in many countries attracted much attention. Thus, in the field of macroeconomics financial issues have gained more prominence over the last two decades. Studies relating to the fiscal deficit have been particularly numerous. The critical size of national public debts, the contribution of the public debt to external debt, the reduced confidence in the state as the guide in socioeconomic development and the role of fiscal policy in adjustment processes are among the main reasons for this increased interest.

scholarly journals 3D-Bioprinting Strategies Based on In Situ Bone-Healing Mechanism for Vascularized Bone Tissue Engineering

Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 287
Author(s):  
Ye Lin Park ◽  
Kiwon Park ◽  
Jae Min Cha
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Healing ◽  
Critical Size ◽  
Current Knowledge ◽  
3D Bioprinting ◽  
The Past ◽  
Regeneration Processes

Over the past decades, a number of bone tissue engineering (BTE) approaches have been developed to address substantial challenges in the management of critical size bone defects. Although the majority of BTE strategies developed in the laboratory have been limited due to lack of clinical relevance in translation, primary prerequisites for the construction of vascularized functional bone grafts have gained confidence owing to the accumulated knowledge of the osteogenic, osteoinductive, and osteoconductive properties of mesenchymal stem cells and bone-relevant biomaterials that reflect bone-healing mechanisms. In this review, we summarize the current knowledge of bone-healing mechanisms focusing on the details that should be embodied in the development of vascularized BTE, and discuss promising strategies based on 3D-bioprinting technologies that efficiently coalesce the abovementioned main features in bone-healing systems, which comprehensively interact during the bone regeneration processes.

scholarly journals Osteoformation potential of an allogenic partially demineralized bone matrix in critical-size defects in the rat calvarium

2021 ◽  
pp. 112207
Author(s):  
Ahmad Moustapha Diallo ◽  
Solène Rota ◽  
Michel Boissière ◽  
Raphaël Bardonnet ◽  
Emmanuel Pauthe ◽  
...  
Keyword(s):  
Critical Size ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Critical Size Defects ◽  
Demineralized Bone

scholarly journals Role of Autologous Platelet Gel (APG) in Bone Healing: A Rabbit Study

2021 ◽  
Vol 11 (1) ◽  
pp. 395
Author(s):  
Antonio Scarano ◽  
Francesco Inchingolo ◽  
Biagio Rapone ◽  
Alberta Greco Lucchina ◽  
Erda Qorri ◽  
...  
Keyword(s):  
Critical Size ◽  
Bone Defects ◽  
New Bone Formation ◽  
Platelet Gel ◽  
Woven Bone ◽  
Rapid Healing ◽  
Rabbit Bone ◽  
Autologous Platelet ◽  
New Zealand Rabbits

Purpose: The aim of the present study is to evaluate the influence and efficacy of autologous platelets on bone regeneration in a rabbit defects model. Materials and Methods: A total of 12 critical size tibial defects were produced in six New Zealand rabbits: A total of six defects were filled with autologous platelet gel (APG) and six defects were maintained as untreated controls. No membranes were used to cover the bone osteotomies. The histology and histomorphometry were performed at four weeks on retrieved samples of both groups. Results: No complications were reported in any of the animals nor for the defects produced. A significantly higher lamellar and woven bone percentage was reported for the APG group with a lower level of marrow spaces (p < 0.05). Evidence of newly formed bone was found in the superficial portion of the bone defect of APG samples where no aspects of bone resorption were observed. Conclusions: The evidence of the present research revealed that APG increases new bone formation restricted to the cortical portion and induces more rapid healing in rabbit bone defects than in untreated defects.

scholarly journals Predicting the Characteristics of Defect Transitions on Curved Surfaces

Soft Matter ◽  
2021 ◽  
Author(s):  
Siddhansh Agarwal ◽  
Sascha Hilgenfeldt
Keyword(s):  
Critical Size ◽  
Complex Function ◽  
Lattice Defects ◽  
Curved Surfaces ◽  
Simple Condition ◽  
Shape Parameters ◽  
Optimal Position

The energetically optimal position of lattice defects on intrinsically curved surfaces is a complex function of shape parameters. For open surfaces, a simple condition predicts the critical size for which...

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