A Two-stage Rotary Blood Pump Design with Potentially Lower Blood Trauma: A Computational Study

2016 ◽  
Vol 39 (4) ◽  
pp. 178-183 ◽  
Author(s):  
Bente Thamsen ◽  
Ricardo Mevert ◽  
Michael Lommel ◽  
Philip Preikschat ◽  
Julia Gaebler ◽  
...  
Author(s):  
M. V. Denisov ◽  
M. Walter ◽  
S. Leonhard ◽  
D. V. Telyshev
Keyword(s):  

2000 ◽  
Vol 24 (6) ◽  
pp. 412-420 ◽  
Author(s):  
Yukihiko Nosé ◽  
M. Yoshikawa ◽  
S. Murabayashi ◽  
T. Takano
Keyword(s):  

Perfusion ◽  
2016 ◽  
Vol 32 (4) ◽  
pp. 264-268
Author(s):  
D. Scott Lawson ◽  
Derek Eilers ◽  
Suzanne Osorio Lujan ◽  
Maria Bortot ◽  
James Jaggers

Background: Current blood pumps used for cardiopulmonary bypass generally fall into two different pump design categories; non-occlusive centrifugal pumps and occlusive, positive-displacement roller pumps. The amount of foreign surface area of extracorporeal circuits correlates with post-operative morbidity due to systemic inflammation, leading to a push for technology that reduces the amount of foreign surfaces. Current roller pumps are bulky and the tubing forms an arc in the pumping chamber (raceway), positioning the inlet 360 degrees from the outlet, making it very difficult to place the pump closer to the patient and to efficiently reduce tubing length. These challenges put existing roller pumps at a disadvantage for use in a compact cardiopulmonary bypass circuit. Centrifugal blood pumps are easier to incorporate into miniature circuit designs. However, the prime volumes of current centrifugal pump designs are large, especially for pediatric extracorporeal circuits where the prime volumes are too great to be of clinical value. Method: We describe a preliminary report on a novel, occlusive, linear, single-helix, positive-displacement blood pump which allows for decreased prime volume and surface area of the extracorporeal circuit. This new experimental pump design was used to perfuse a 6 kilogram piglet with a pediatric cardiopulmonary bypass circuit for two hours of continuous use. Blood samples were obtained every thirty minutes and assayed for plasma free hemolysis generation. Conclusions: The results from this initial experiment showed low plasma free hemoglobin generation and encourages the authors to further develop this concept.


2018 ◽  
Vol 8 (8) ◽  
pp. 1275 ◽  
Author(s):  
Kai von Petersdorff-Campen ◽  
Yannick Hauswirth ◽  
Julia Carpenter ◽  
Andreas Hagmann ◽  
Stefan Boës ◽  
...  

Conventional magnet manufacturing is a significant bottleneck in the development processes of products that use magnets, because every design adaption requires production steps with long lead times. Additive manufacturing of magnetic components delivers the opportunity to shift to agile and test-driven development in early prototyping stages, as well as new possibilities for complex designs. In an effort to simplify integration of magnetic components, the current work presents a method to directly print polymer-bonded hard magnets of arbitrary shape into thermoplastic parts by fused deposition modeling. This method was applied to an early prototype design of a rotary blood pump with magnetic bearing and magnetic drive coupling. Thermoplastics were compounded with 56 vol.% isotropic NdFeB powder to manufacture printable filament. With a powder loading of 56 vol.%, remanences of 350 mT and adequate mechanical flexibility for robust processability were achieved. This compound allowed us to print a prototype of a turbodynamic pump with integrated magnets in the impeller and housing in one piece on a low-cost, end-user 3D printer. Then, the magnetic components in the printed pump were fully magnetized in a pulsed Bitter coil. The pump impeller is driven by magnetic coupling to non-printed permanent magnets rotated by a brushless DC motor, resulting in a flow rate of 3 L/min at 1000 rpm. For the first time, an application of combined multi-material and magnet printing by fused deposition modeling was shown. The presented process significantly simplifies the prototyping of products that use magnets, such as rotary blood pumps, and opens the door for more complex and innovative designs. It will also help postpone the shift to conventional manufacturing methods to later phases of the development process.


Author(s):  
Thananya Khienwad ◽  
Ronnachit Deepankaew ◽  
Praemai Wannawat ◽  
Phornphop Naiyanetr
Keyword(s):  

2018 ◽  
Vol 42 (12) ◽  
pp. 1119-1124 ◽  
Author(s):  
Gerson Rosenberg ◽  
Christopher A. Siedlecki ◽  
Choon-Sik Jhun ◽  
William J. Weiss ◽  
Keefe Manning ◽  
...  

ASAIO Journal ◽  
2011 ◽  
Vol 57 (3) ◽  
pp. 158-163 ◽  
Author(s):  
Ruedger Kopp ◽  
Ralf Bensberg ◽  
Jutta Arens ◽  
Ulrich Steinseifer ◽  
Thomas Schmitz-Rode ◽  
...  

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