Diagnostic precision of a microscope-integrated intraoperative OCT device in patients with epiretinal membranes

2017 ◽  
Vol 28 (3) ◽  
pp. 329-332 ◽  
Author(s):  
Christoph Leisser ◽  
Nino Hirnschall ◽  
Christoph Hackl ◽  
Birgit Döller ◽  
Ralph Varsits ◽  
...  

Purpose: Preoperative and postoperative optical coherence tomography (OCT) of macular pathologies can be regarded as the gold standard diagnostic technique, providing detailed information on the microstructures of the macula for planning the surgical procedure and comparing improvements after surgery in the follow-up period. Intraoperative use of OCT is a novel application to support surgeons during macular surgery. The aim of this study was to examine the diagnostic precision of a microscope-integrated intraoperative spectral-domain OCT (i-OCT) device and compare imaging results to a stand-alone spectral-domain OCT (SD-OCT) device. Methods: This prospective study included 41 eyes of 41 patients scheduled for pars plana vitrectomy with membrane peeling due to an idiopathic epiretinal membrane (ERM). Intraoperative imaging with the i-OCT device was performed at the beginning of the surgery and compared to preoperative SD-OCT images. Results: Preoperative and intraoperative SD-OCT evaluations showed high intraobserver and interobserver reproducibility for the presence of ERM, lamellar macular hole, and vitreomacular traction. For intraretinal cystoid changes, intraobserver and interobserver reproducibility for both OCTs was rather poor, mainly due to microcystic changes. Conclusions: Intraoperative spectral-domain OCT offers high reproducibility regarding the visibility of ERM, lamellar macular holes, and vitreomacular traction. Microcystic changes cause discrepancies in interpretation, often simply diagnosed as retinal thickening.

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yoreh Barak ◽  
Mark A. Ihnen ◽  
Shlomit Schaal

The introduction of spectral domain optical coherence tomography (SD-OCT) has enhanced Vitreoretinal Interface (VRI) imaging considerably and facilitated the diagnosis, followup, prognosis determination, and management of VRI-associated pathologies. HR-OCT became a common practical tool seen in almost every ophthalmology practice. Knowledge of SD-OCT image interpretation and recognition of pathologies are required for all ophthalmologists. This paper methodically reviews the normal aging process of the VRI and discusses several commonly encountered VRI pathologies. The role of SD-OCT imaging in VRI-associated disorders such as posterior vitreous detachment, vitreomacular traction syndrome, idiopathic epiretinal membranes, lamellar holes, pseudoholes, and full thickness macular holes is portrayed. Future perspectives of new OCT technologies based on SD-OCT are discussed.


2007 ◽  
Vol 38 (4) ◽  
pp. 330-332 ◽  
Author(s):  
Omar S. Punjabi ◽  
Harry W. Flynn Jr. ◽  
Robert W. Knighton ◽  
Carmen A. Puliafito ◽  
John L. Legarreta ◽  
...  

2018 ◽  
Vol 236 (07) ◽  
pp. 877-884 ◽  
Author(s):  
Daniela Claessens ◽  
Alexander K. Schuster

Zusammenfassung Hintergrund Zur Erfassung von Metamorphopsien steht im klinischen Alltag der Amsler-Test zur Verfügung. Dieser erfasst qualitativ Metamorphopsien, zur Quantifizierung von Metamorphopsien und als Verlaufskontrolle wurde der computerbasierte Test „AMD – A Metamorphopsia Detector®“ entwickelt. Das Ziel dieser Studie ist zu untersuchen, ob eine Korrelation zwischen zentraler Netzhautdicke (CRT, gemessen mittels Spectral Domain OCT) und quantifizierter Metamorphopsiemessung bei Patienten mit exsudativer altersassoziierter Makuladegeneration (AMD) und diabetischem Makulaödem (DMÖ) besteht. Material und Methoden 66 Augen von 66 Patienten (DMÖ: 19 [11 Männer, 8 Frauen; Alter 42 – 76 Jahre]; AMD: 47 [13 Männer, 34 Frauen; Alter 56 – 93 Jahre]) wurden in dieser explorativen Pilotstudie untersucht und in Hinblick auf das Vorliegen eines Makulaödems (zentrale 500-µm-Zone, Cirrus HD-OCT) klassifiziert. Bestkorrigierter monokularer Fernvisus (BCVA), Amsler-Test, Metamorphopsiemessung (AMD – A Metamorphopsia Detector) mit Angabe des Metamorphopsie-Index (MI), binokulare Ophthalmoskopie, SD-OCT mit Messung der zentralen Netzhautdicke (CRT) und ggf. Fluoreszenzangiografie wurden durchgeführt. Die Korrelation von CRT und MI wurde mittels Spearman-Korrelation geprüft. Ergebnisse BCVA bei DMÖ bzw. AMD betrug (logMAR) 0,27 (SD 0,3) bzw. 0,29 (SD 0,2). Bei Augen mit DMÖ zeigte sich eine Korrelation von MI und CRT mit rho = 0,88 (p < 0,001) und bei Augen mit AMD betrug rho = 0,56 (p < 0,001). Schlussfolgerung Die Korrelation von CRT und MI war bei DMÖ hoch und bei AMD moderat. Künftige Studien sollen untersuchen, ob sich die Metamorphopsiemessung zur Detektion einer Konversion in eine exsudative AMD eignet und ob dies eine Messung zur Verlaufskontrolle, ggf. als Selbsttest ermöglicht.


2020 ◽  
Author(s):  
Lian Tan ◽  
Yanling Long ◽  
Ziyang Li ◽  
Xi Ying ◽  
Jiayun Ren ◽  
...  

Abstract Background: To report the prevalence of ocular abnormalities and investigate visual acuity in a large Western China cohort of retinitis pigmentosa (RP) patients.Methods: A retrospective study was performed, reviewing the medical records and ophthalmic examination reports of 2,127 eyes from 1,065 RP patients in one eye hospital. The authors investigated the prevalence of ocular abnormalities and the relationship between best corrected visual acuity (BCVA) and macular abnormalities.Results: Nyctalopia (58.2%) and blurred vision (27.1%) were the leading consultation causes. BCVA measurements in the better eyes at first clinical presentation showed that 304 patients (28.5%) were categorised as blind and 220 patients (20.7%) as low vision. The most common ocular abnormalities were cataracts (43.1%) and macular abnormalities (59.7%), including epiretinal membranes (51.1%), cystoid macular oedema (18.4%), vitreomacular traction syndrome (2.4%), macular holes (2.3%) and choroidal neovascular membranes (0.05%). Glaucoma was found in 35 eyes (1.6%). The proportions of epiretinal membranes (P = 0.001) and macular holes (P = 0.008) increased significantly with age. The proportions of vitreomacular traction syndrome (P = 0.003) and epiretinal membranes (P < 0.001) in pseudophakia and aphakia eyes were significantly higher than in eyes that had not received operations (including cataracts and clear lens). Cystoid macular oedema was significantly associated with poorer visual acuity in RP patients with clear lens (P = 0.002).Conclusion: Cataracts and macular abnormalities are common in RP patients. In the macular abnormalities, cystoid macular oedema may have a negative effect on BCVA in RP patients with clear lens.


2017 ◽  
Vol 11 (1) ◽  
pp. 334-345 ◽  
Author(s):  
Heba Radi AttaAllah ◽  
Ismail Ahmed Nagib Omar ◽  
Ahmed Shawkat Abdelhalim

Purpose: Spectral Domain Optical Coherence Tomography (SD-OCT) was used to evaluate retinal and vitreo-retinal changes that occur in highly myopic patients. Methods: This prospective study included 472 eyes of 472 patients suffering from high myopia (> -6.00 D), between May 2012 and December 2015. All patients were examined, using Cirrus HD OCT (Zeiss Cirrus TM HD-OCT model 4000), to detect any retinal or vitreo-retinal interface abnormalities. All obtained data was analyzed using Statistical Package for the Social Sciences software version 17 (SPSS Inc, Chicago, IL, USA) and the paired two-sided t-test. Bivariate correlations were performed between different parameters using the Spearman correlation coefficient (r). Results: Mean spherical equivalent (MSE) was -13.11± 4.35D. Mean axial length (AL) was 28.5±1.62 mm. Posterior vitreous detachment (PVD) was the most frequent OCT finding; representing 33.4% of the cases, 13.7% of them were associated with macular traction. A statistically significant positive correlation was found between AL and MTM, full thickness macular hole, PVD with traction, and dome shaped macula (r = 0.49 and P = 0.001, r = 0.422 and P = 0.0001, r = 0.25 and P = 0.03, r=0.475, P=0.001 respectively) Conclusion: OCT is a valuable tool in detecting retinal and vitreo-retinal interface abnormalities in highly myopic eyes, and it can be used for follow up of those patients to avoid advanced retinal damage.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Cristina Georgeon ◽  
Ilanite Marciano ◽  
Roxane Cuyaubère ◽  
Otman Sandali ◽  
Nacim Bouheraoua ◽  
...  

Objective. To compare the results and repeatability of the corneal thickness (CT) and epithelial thickness (ET) maps provided by Swept-Source-Optical Coherence Tomography with those of Spectral-Domain-OCT in normal eyes. Methods. 30 normal eyes of 30 patients were assessed by 3 trained operators with SS-OCT and SD-OCT. Results. The central and minimum ET obtained with both devices were correlated: central ET, r = 0.86, p < 0.05 ; minimum ET, r = 0.72, p < 0.05 . Compared with SD-OCT, SS-OCT tended to underestimate these figures by 1.4 and 1.9 μm on average. The central and minimum CT obtained with both devices were strongly correlated: central CT, r = 0.994, p < 0.05 ; minimum CT, r = 0.995, p < 0.05 . SS-OCT tended to overestimate these figures by 11 and 14 μm on average. Repeatability was good for both devices with a mean coefficient of variation of measurements <6% for ET and <2% for CT. Interoperator variability (standard deviation and COV) was significantly higher for SS-OCT than for SD-OCT for all local epithelial thicknesses and significantly lower for the central CT and several local corneal thicknesses, whereas no significant differences between both technologies were found for the central and minimum ET and the minimum CT. Conclusion. SS-OCT and SD-OCT provide reproducible measurements of CT and ET in normal corneas with a strong correlation between both technologies. However, both technologies are not interchangeable when the main thickness parameters (i.e., central and minimum CT and minimum ET) are used for diagnosing early keratoconus or calculating the expected residual stromal bed thickness before corneal refractive surgery or anterior lamellar keratoplasty.


2021 ◽  
pp. 62-64
Author(s):  
Samra Wahaj Fatima ◽  
M M M Baig ◽  
Superna Mahender ◽  
M. Geetanjali ◽  
Mohammed Ather

Purpose: To compare RNLF structural changes by Spectral Domain- OCT and functional visual eld defects by automated perimetry in Primary Open Angle Glaucoma cases Materials And Methods: A prospective and comparative study was conducted to quantitatively measure the peripapillary retinal nerve ber layer thickness using SD-OCT and compared it with eld changes plotted by Humphrey Field analyser 24-2. The study was conducted at the department of Glaucoma of a tertiary eye care hospital for a period of one year. 60 eyes of 30 patients who diagnosed to have POAG between the age group of 40-65 were included in the study. Patients having substantial media opacity, Retinal pathology and who underwent intra ocular surgeries were excluded from the study. Informed consent obtained from patients who were included in the study. All were examined using Slit lamp, Snellen's chart, Applanation tonometer, Gonioscope, 90 D slit lamp biomicroscope to study Fundus oculi. Fields were plotted using Humphrey eld analyser 24-2 , RNFL thickness measured using SD-OCT. Results: 60 eyes of 30 patients 19 were males 11 were females. 14(23.33%) eyes showed normal visual elds but there was thinning of RNFL was noted in SD-OCT. 41 eyes (68.3%) had visual eld defects which corresponded to thinning of RNFL in that quadrant. 5 eyes (8.3%) showed advanced eld changes and had corresponding thinning of RNFL in that quadrant. Discussion: Results of this study shows a signicant difference in RNFL thickness among all three grades of glaucoma. It was observed that the average RNFL thickness value in moderate glaucoma (66.34 microns) and all quadrant thickness values were similar to Sihota et al study (RNFL-66.07 microns). The mean RNFL thickness +/- Sd (58 +/-5.52) in advanced glaucoma of present study were closely similar with the ndings of Sihota et al study (53.65 +/-14.2). Conclusion: It is concluded that RNFL thickness changes corresponds to Field changes plotted on Humphrey eld analyser in moderate glaucoma. Even in mild cases changes RNFL thickness is noted even though the elds plotted on Humphrey eld analyser doesn't show any changes. So RNFL thickness can be taken as Pre perimetric changes as diagnostic criteria for the diagnosis of POAG.


2015 ◽  
Vol 4 (45) ◽  
pp. 7833-7838
Author(s):  
Dhwani Garg ◽  
Neelima Mehrotra ◽  
Arvind Ram ◽  
Sharma B D ◽  
Akhil Agarwal ◽  
...  

2015 ◽  
Vol 9 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Carolina P.B Gracitelli ◽  
Ricardo Y Abe ◽  
Felipe A Medeiros

Identification of structural damage to the optic nerve and retinal nerve fiber layer (RNFL) is an essential component of diagnosis and management of glaucoma. The introduction of spectral-domain OCT (SD-OCT) has allowed objective quantification of damage to these structures with unprecedented resolution. In addition, recent attention has been directed towards imaging the macular area for quantifying loss of neural tissue caused by the disease. Many studies have evaluated and compared the diagnostic accuracies of a variety of parameters that can be obtained from imaging these areas of the ocular fundus. In this article, we critically review the existing literature evaluating the diagnostic accuracy of SD-OCT in glaucoma and we discuss issues related to how SD-OCT results should be incorporated into clinical practice.


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