Optical Coherence Tomography Imaging in the Management of the Argus II Retinal Prosthesis System

2017 ◽  
Vol 27 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Francesco Parmeggiani ◽  
Katia De Nadai ◽  
Angela Piovan ◽  
Andrea Binotto ◽  
Sara Zamengo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinitis Pigmentosa ◽  
Real Life ◽  
Case Series ◽  
Retinal Prosthesis ◽  
Implant Design ◽  
Pathologic Myopia ◽  
Optical Coherence ◽  
Argus Ii ◽  
Blind Patients

Purpose To report a real-life experience with the Argus II retinal prosthesis system in blind patients with end-stage retinitis pigmentosa (RP) or choroideremia (CHM), focusing on the pivotal role of optical coherence tomography (OCT) in both preoperative and postoperative management. Methods This hospital-based case series included 3 blind patients who were uneventfully implanted with Argus II epiretinal device. These patients (2 with RP and 1 with CHM) were selected during the Argus™ II Retinal Prosthesis System PostMarket Surveillance Study Protocol. Complete screening procedures had involved 66 eyes of 33 patients afferent to the Center for Retinitis Pigmentosa of the Veneto Region. Results Preoperative OCT examination resulted in the exclusion of 8 eyes in 4 patients with bilateral posterior staphyloma diagnosing unexpected staphylomatous macular patterns in 2 patients with RP and no sign of pathologic myopia. Postoperative OCT study of Argus II proximity to retinal surface indicated a plausible correlation between electrode–retina distance and perceptual threshold in 2 of our 3 patients. In particular, during the first 6 months of follow-up, the patient with the closest contact between device and macula showed a continuous vision-related improvement in the performance of several real-life tasks. Conclusions The present findings illustrate the modalities by which each different OCT examination is an essential tool to optimize safety and efficacy profiles during Argus II protocol. Optical coherence tomography will be crucial for future investigative approaches on patient selection criteria and next-generation implant design.

Correlation between Argus II array–retina distance and electrical thresholds of stimulation is improved by measuring the entire array

2019 ◽  
pp. 112067211988579 ◽  
Author(s):  
Lucy T Xu ◽  
Aleksandra V Rachitskaya ◽  
Meghan J DeBenedictis ◽  
James Bena ◽  
Shannon Morrison ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Measurement Method ◽  
Case Series ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Four Corners ◽  
Argus Ii ◽  
Programming Software ◽  
Entire Array ◽  
Electrode Stimulation

Purpose: To describe two methods of measuring Argus II array–retina distance and to correlate array–retina distance to electrode stimulation thresholds. Methods: This was a case series of eight patients implanted with the Argus II. Spectral domain-optical coherence tomography array–retina distance was measured by two methods and correlated to corresponding electrode thresholds: (1) array–retina distance at each array corner and the largest array–retina distance and (2) using manual optical coherence tomography segmentation, the average array–retina distance was determined for each group of four electrodes. Patients 1–5 and 6–8 were analyzed separately due to a different threshold programming software. Results: The Spearman’s rank coefficient between array–retina distance and thresholds was −0.006 ( p = 0.98) for patients 1–5, and 0.16 ( p = 0.59) for patients 6–8 with the first method. The Spearman’s rank coefficient was 0.25 ( p < 0.001) for patients 1–5 and 0.36 ( p < 0.001) for patients 6–8 with the second method. Conclusion: There is a positive correlation between array–retina distance and threshold measurements when measuring the entire array but not when using a faster measurement method of four corners and largest array–retina distance.

scholarly journals Intra-operative microscope-integrated swept-source optical coherence tomography guided placement of Argus II retinal prosthesis

2016 ◽  
Vol 95 (5) ◽  
pp. e431-e432 ◽  
Author(s):  
Dilraj S. Grewal ◽  
Oscar M. Carrasco-Zevallos ◽  
Randall Gunther ◽  
Joseph A. Izatt ◽  
Cynthia A. Toth ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Prosthesis ◽  
Optical Coherence ◽  
Swept Source ◽  
Argus Ii ◽  
Operative Microscope

Feasibility and Clinical Utility of Ultra-Widefield–Navigated Swept-Source Optical Coherence Tomography Imaging

2021 ◽  
pp. 247412642199733
Author(s):  
Kyle D. Kovacs ◽  
M. Abdallah Mahrous ◽  
Luis Gonzalez ◽  
Benjamin E. Botsford ◽  
Tamara L. Lenis ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Clinical Utility ◽  
Clinical Decision Making ◽  
Imaging System ◽  
Imaging Modality ◽  
Case Series ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Swept Source ◽  
Oct Imaging

Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.

Spectral Domain Optical Coherence Tomography Findings in a Case Series of Patients with Bilateral Diffuse Uveal Melanocytic Proliferation

2014 ◽  
Vol 22 (6) ◽  
pp. 490-493 ◽  
Author(s):  
Zaid Shalchi ◽  
Manoharan Shunmugam ◽  
Omar A. Mahroo ◽  
Robert J. McDonald ◽  
Mahmut Dogramaci ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Spectral Domain ◽  
Optical Coherence

Line‐field confocal optical coherence tomography of sebaceous hyperplasia: a case series

2021 ◽  
Author(s):  
Clément Lenoir ◽  
Gwendoline Diet ◽  
Elisa Cinotti ◽  
Linda Tognetti ◽  
Carmen Orte Cano ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Line Field

Line‐field confocal optical coherence tomography for non‐invasive diagnosis of lichenoid dermatoses of the childhood: A case series

2021 ◽  
Author(s):  
Linda Tognetti ◽  
Andrea. Carraro ◽  
Elisa Cinotti ◽  
Mariano Suppa ◽  
Veronique Marmol ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Line Field ◽  
Non Invasive
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