Laser Peripheral Iridotomy Changes Anterior Chamber Architecture

2016 ◽  
Vol 27 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Christian Theinert ◽  
Peter Wiedemann ◽  
Jan D. Unterlauft
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Angle Closure ◽  
Control Group ◽  
Threshold Values ◽  
Characteristic Analysis ◽  
Laser Peripheral Iridotomy ◽  
Peripheral Iridotomy ◽  
Healthy Eyes

Purpose The pressure gradient between anterior and posterior chamber in acute angle closure (AAC) and primary angle closure suspects is balanced by a sufficient laser peripheral iridotomy (LPI). The anterior chamber changes induced by LPI in patients with unilateral AAC were examined and compared to healthy eyes to define threshold values, which may help to discriminate between healthy and diseased eyes. Methods Using Scheimpflug photography, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and central corneal thickness (CCT) were measured before and after LPI in both eyes of unilateral AAC cases. These measurements were compared to a group of healthy control eyes to determine threshold values for ACD, ACV, and ACA. Results The ACD, ACV, and ACA increased significantly in the 25 AAC eyes after LPI. The ACD, ACV, ACA, and CCT values in the AAC eyes obtained before LPI were compared to a control group of 59 healthy eyes with wide open chamber angles. The cutoff values revealed by receiver operating characteristic analysis were 2.1 mm for ACD, 90.5 mm2 for ACV, and 27.25° for ACA. Conclusions Our results confirm the significant changes of the anterior segments architecture induced by LPI in AAC eyes. The found threshold values for ACD, ACV, and ACA may help in daily clinical routine to discriminate between healthy eyes and those in need for a prophylactic LPI.

Bilateral laser peripheral iridotomy in a co-occurrence of unilateral iridocorneal endothelial syndrome and chronic angle closure glaucoma

2021 ◽  
pp. 112067212110678
Author(s):  
Navjot Singh Ahluwalia ◽  
Rakesh Shakya ◽  
Dhairya Parikh ◽  
Devindra Sood
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Specular Microscopy ◽  
Laser Peripheral Iridotomy ◽  
First Case ◽  
Peripheral Iridotomy ◽  
Iris Atrophy

Purpose To report a case of unilateral Iridocorneal endothelial (ICE) syndrome- Progressive iris atrophy (PIA) with an overlapping chronic angle closure glaucoma (CACG) and to highlight the effect of bilateral Laser peripheral iridotomy (LPI) in such a co-occurrence. Case description A patient presented to us with bilateral gradual painless progressive diminution of vision. Both eyes (BE) had a clear cornea, shallow peripheral anterior chamber depth, grade 2 nuclear sclerosis, raised intraocular pressure and glaucomatous optic neuropathy. In addition, the Left eye (LE) had an irregular anterior chamber, peripheral anterior synechiae (PAS) extending to cornea, patchy iris atrophy, subtle corectopia and a low endothelial cell count on specular microscopy. Indentation gonioscopy led to the diagnoses of CACG BE with ICE syndrome- PIA LE. LPI was performed bilaterally. On Anterior Segment Optical Coherence Tomography (ASOCT), there was evident widening of the angle away from PAS in the Right eye as well as in the LE with PIA post LPI. Conclusion This is a unique case of unilateral PIA with an associated CACG in BE. It is the first case demonstrating the effect of bilateral LPI in such a case scenario. Though not indicated in ICE syndrome, LPI did show short term evidence of significant widening of the angle away from areas of PAS even in the eye with PIA having a limited high PAS and a concurrent primary (chronic) angle closure disease.

scholarly journals Evaluation of Anterior Segment’s Structures in Tilted Disc Syndrome

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Ercan Ozsoy ◽  
Abuzer Gunduz ◽  
Ersin Ersan Demirel ◽  
Tongabay Cumurcu
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Control Group ◽  
Tilted Disc Syndrome ◽  
Chamber Volume ◽  
Significant Difference ◽  
Tilted Disc

Purpose. To evaluate anterior segment’s structures by Pentacam in patients with tilted disc syndrome (TDS).Methods. Group 1 included forty-six eyes of forty-six patients who have the TDS. Group 2 including forty-six eyes of forty-six cases was the control group which was equal to the study group in age, gender, and refraction. A complete ophthalmic examination was performed in both groups. All cases were evaluated by Pentacam. The axial length (AL) of eyes was measured by ultrasound. Quantitative data obtained from these measurements were compared between two groups.Results. There was no statistically significant difference for age, gender, axial length, and spherical equivalent measurements between two groups (p=0.625,p=0.830,p=0.234, andp=0.850). There was a statistically significant difference for central corneal thickness (CCT), corneal volume (CV), anterior chamber angle (ACA), and pupil size measurements between two groups (p=0.001,p=0.0001,p=0.003, andp=0.001). Also, there was no statistically significant difference for anterior chamber depth (ACD), anterior chamber volume (ACV), and lens thickness (LT) measurements between two groups (p=0.130,p=0.910, andp=0.057).Conclusion. We determined that CCT was thinner, CV was less, and ACA was narrower in patients with TDS. There are some changes in the anterior segment of the eyes with tilted disc.

scholarly journals Effects of Laser Peripheral Iridotomy in Subgroups of Primary Angle Closure Based on Iris Insertion

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sung-Cheol Yun ◽  
Ji Wook Hong ◽  
Kyung Rim Sung ◽  
Jin Young Lee
Keyword(s):  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Multivariate Regression Analysis ◽  
Angle Closure ◽  
Laser Peripheral Iridotomy ◽  
Factors Affecting ◽  
Primary Angle Closure ◽  
Before And After ◽  
Qualitative Classification ◽  
Peripheral Iridotomy

Purpose. To investigate the effect of laser peripheral iridotomy (LPI) in subgroups of primary angle closure based on iris insertion configuration.Methods. Anterior segment optical coherence tomography (AS-OCT) images were obtained before and two weeks after LPI. Qualitative classification of angle closure eyes according to iris insertion (basal insertion group (BG) and nonbasal insertion group (NBG)) was performed. Anterior chamber depth (ACD), lens vault (LV), iris curvature, iris area, iris thickness (IT750), and angle opening distance (AOD750) 750 microns from scleral spur were calculated. Uni- and multivariate regression analysis was carried out to evaluate factors associated with AOD750before and after LPI.Results. Ninety-two eyes of 92 subjects were categorized as NBG (39 eyes) or BG (53 eyes). The mean change after LPI was not significantly different between two groups in all parameters. In both groups, AOD750was affected by ACD (p<0.001,p=0.044) before LPI. AOD750was affected by LV (p=0.012) in NBG, but by ACD (p<0.001) and IT750(p=0.039) in BG after LPI.Conclusions. The outcomes of LPI are not significantly different between angle closure subgroups with different iris insertions. However, factors affecting AOD750show differences between two subgroups after LPI.

scholarly journals Is Hyperopia an Important Risk Factor for PACG in the Dutch Population?—A Case Control Study

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Saskia H. M. van Romunde ◽  
Gijs Thepass ◽  
Hans G. Lemij
Keyword(s):  
Logistic Regression ◽  
Risk Factor ◽  
Refractive Error ◽  
Significant Risk ◽  
Anterior Chamber Depth ◽  
Significant Risk Factor ◽  
Angle Closure ◽  
Control Group ◽  
Dutch Population ◽  
Laser Peripheral Iridotomy

Objectives. To determine if hyperopia is a risk factor for primary angle-closure glaucoma (PACG) in the Dutch population and to identify other biometrical parameters as risk factors for PACG including axial length (AL), anterior chamber depth (ACD), andkvalues.Methods. The study population consisted of PACG patients that had undergone a laser peripheral iridotomy (LPI). The control group consisted of age- and gender-matched cataract patients. The main outcome was hyperopia (spherical equivalent ≥+0.5 dioptres) measured with IOL Master or autorefractor. Refractive error, ACD, AL, andkvalues were tested with a Mann-WhitneyUtest and by logistic regression.Results. 117 PACG patients and 234 controls were included (mean age = 80 years ± 3.6). The prevalence of hyperopia in patients and controls was 69.6% and 61.1%, respectively (Fisher’s testP=0.076). Mann-WhitneyUtest showed no statistically significant relation with refractive error (P=0.068) orkvalues (P=0.607). In contrast, ACD and AL were statistically significant (P<0.001). Tested with logistic regression, only ACD was a significant predictor of PACG (P<0.001).Conclusion. There was no statistically significant correlation between refractive error and PACG. ACD was strongly correlated, though, with PACG, whereas AL turned out to be a less significant risk factor.

scholarly journals Peripheral Anterior Chamber Depth and Screening Techniques for Primary Angle Closure Disease in Community Elderly Chinese

2020 ◽  
Author(s):  
Qin Luo ◽  
Wenwen Xue ◽  
Yin Yuan ◽  
Chaowei Fu ◽  
Jiangnan He ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Angle Closure ◽  
Screening Methods ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Elderly Chinese

Abstract Background To investigate the distribution of peripheral anterior chamber depth (ACD) and the relationship between peripheral ACD and gonioscopy compared to other ocular parameters for primary angle closure disease (PACD) screening. Methods Cross-sectional study. Adults 50 and older were enrolled from a population-based study using cluster random sampling in Pudong New District, Shanghai. Remote ocular screening was performed with digital anterior eye structure photography. Van Herrick measurements were used to evaluate the peripheral ACD, the depth of the peripheral anterior chamber, and corneal thickness (CT), and the ACD to CT ratio was calculated. Subjects with peripheral ACD less than 0.5 CT were made follow-up appointments for clinical examination with gonioscopy. Receiver operating characteristic curves (ROC) were generated to show the performance of different tests in screening for primary angle closure disease (PACD). Results 2528 adults participated in the study with 91 patients diagnosed with PACD. 2463 subjects had valid data in the right eye available for analysis. The mean peripheral ACD values for men and women were significantly different: 1.04±0.46 (range 0.11-2.93) CT and 0.87±0.41 (range 0.12-2.96) CT respectively (t=-4.18; P<0.0001). Multivariate logistic regression analysis reveals that peripheral ACD declined by 0.31 CT (P<0.0001) per diopter of SE and was 0.19 CT (P<0.0001) shallower in women than in men (r2=0.1304, P<0.0001). Peripheral ACD performed best in screening for PACD. Conclusions Peripheral ACD measurement is recommended for PACD screening in community elderly Chinese.

scholarly journals Peripheral Anterior Chamber Depth and Screening Techniques for Primary Angle Closure Disease in Community Elderly Chinese

2020 ◽  
Author(s):  
Qin Luo ◽  
Wenwen Xue ◽  
Yin Yuan ◽  
Chaowei Fu ◽  
Jiangnan He ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Angle Closure ◽  
Screening Methods ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Elderly Chinese

Abstract Background To investigate the distribution of peripheral anterior chamber depth (ACD) and the relationship between peripheral ACD and gonioscopy compared to other ocular parameters for primary angle closure disease (PACD) screening. Methods Cross-sectional study. Adults 50 and older were enrolled from a population-based study using cluster random sampling in Pudong New District, Shanghai. Remote ocular screening was performed with digital anterior eye structure photography. Van Herrick measurements were used to evaluate the peripheral ACD, the depth of the peripheral anterior chamber, and corneal thickness (CT), and the ACD to CT ratio was calculated. Subjects with peripheral ACD less than 0.5 CT were made follow-up appointments for clinical examination with gonioscopy. Receiver operating characteristic curves (ROC) were generated to show the performance of different tests in screening for primary angle closure disease (PACD). Results 2528 adults participated in the study with 91 patients diagnosed with PACD. 2463 subjects had valid data in the right eye available for analysis. The mean peripheral ACD values for men and women were significantly different: 1.04±0.46 (range 0.11-2.93) CT and 0.87±0.41 (range 0.12-2.96) CT respectively (t=-4.18; P<0.0001). Multivariate logistic regression analysis reveals that peripheral ACD declined by 0.31 CT (P<0.0001) per diopter of SE and was 0.19 CT (P<0.0001) shallower in women than in men (r2=0.1304, P<0.0001). Peripheral ACD performed best in screening for PACD. Conclusions Peripheral ACD measurement is recommended for PACD screening in community elderly Chinese.

scholarly journals Peripheral Anterior Chamber Depth and Screening Techniques for Primary Angle Closure Disease in Community Elderly Chinese

2020 ◽  
Author(s):  
Wenwen Xue ◽  
Qin Luo ◽  
Yin Yuan ◽  
Chaowei Fu ◽  
Jiangnan He ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Cross Sectional Study ◽  
Angle Closure ◽  
Cross Sectional ◽  
Primary Angle Closure ◽  
Elderly Chinese

Abstract Purpose To investigate the distribution of peripheral anterior chamber depth (ACD) and the relationship between peripheral ACD and gonioscopy compared to other ocular parameters (peripheral ACD, spherical equivalent [SE], intraocular pressure [IOP]) for primary angle closure disease (PACD) screening in an elderly Chinese community. Methods Cross-sectional study. Adults 50 and older were enrolled from a population-based study using cluster random sampling in Pudong New District, Shanghai. Remote ocular screening was performed with digital anterior eye structure photography. Van Herrick measurements were used to evaluate the peripheral ACD, the depth of the peripheral anterior chamber, and corneal thickness (CT), and the ACD to CT ratio was calculated. Subjects with peripheral ACD less than 0.5 CT were made follow-up appointments for clinical examination with gonioscopy. Receiver operating characteristic curves (ROC) were generated to show the performance of different tests in screening for primary angle closure disease (PACD). Results 2528 adults participated in the study with 91 patients diagnosed with PACD. 2463 subjects had valid data in the right eye available for analysis. The mean peripheral ACD values for men and women were significantly different: 1.04±0.46 (range 0.11-2.93) CT and 0.87±0.41 (range 0.12-2.96) CT respectively (t=-4.18; P<0.0001). Multivariate logistic regression analysis reveals that peripheral ACD declined by 0.31 CT (P<0.0001) per diopter of SE and was 0.19 CT (P<0.0001) shallower in women than in men (r2=0.1304, P<0.0001). Peripheral ACD performed best in screening for PACD. Conclusions Peripheral ACD measurement is recommended for PACD screening in community elderly Chinese.

scholarly journals Comparison of Anterior Chamber Parameters between Normal and Keratoconus Eyes using Scheimpflug Photography

2016 ◽  
Vol 5 (3) ◽  
pp. 105-108
Author(s):  
Nagla Hassan Ali ◽  
Mohammed Othman AbdElKhalek ◽  
Hanan Elghoneimy
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Progressive Increase ◽  
Control Group ◽  
Ophthalmological Examination ◽  
Scheimpflug Photography ◽  
Scheimpflug Camera ◽  
Chamber Volume ◽  
Group I

ABSTRACT Aim To evaluate anterior chamber indices including anterior chamber depth (ACD) and anterior chamber volume (ACV) with the progression of keratoconus using a rotating Scheimpflug camera to determine the sensitivity and specificity of these parameters in discriminating keratoconus from normal eyes. Materials and methods After full ophthalmological examination in the Memorial Institute of Ophthalmic Research, the patients are divided into two groups: Group I consisting of 50 eyes of normal control. Group II consists of 50 eyes of moderate keratoconus. All the subjects were evaluated with a Pentacam Scheimpflug camera (Oculus, Wetzlar, Germany). Keratoconic eyes were evaluated by vertical asymmetry (VI), keratoconus index (KI), thinnest corneal thickness (TCT) with front elevation at thinnest location (F.Ele.Th) and back elevation at thinnest location (B.Ele.Th) and then divided into three groups according to mean keratometer (K) readings: Mild (K = less than 47.0 D), moderate (K = 47.0 to 52.0 D), and severe (K = 52.0 D or higher), and ACD and ACV were obtained after exclusion of mild and severe cases. Results With the progression of the disease, there was statistically significant differences in ACD and ACV measurements between the normal and moderate keratoconus eyes with progressive increase in the ACD and ACV with disease progression. Conclusion Anterior chamber parameters including depth and volume showed significant increase with moderate keratoconus than control. How to cite this article Ali NH, AbdElKhalek MO, El Ghonemy HM. Comparison of Anterior Chamber Parameters between Normal and Keratoconus Eyes using Scheimpflug Photography. Int J Kerat Ect Cor Dis 2016;5(3):105-108.

scholarly journals Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Wakako Ikegawa ◽  
Takashi Suzuki ◽  
Koji Namiguchi ◽  
Shiro Mizoue ◽  
Atsushi Shiraishi ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Anterior Chamber Angle ◽  
Laser Peripheral Iridotomy ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Before And After ◽  
The Mean ◽  
Peripheral Iridotomy

Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.

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