Intravitreal Injection of Recombinant Tissue Plasminogen Activator in Submacular Hemorrhage: Case Series

2016 ◽  
Vol 26 (3) ◽  
pp. e49-e51 ◽  
Author(s):  
Joana Araújo ◽  
Cristina Sousa ◽  
Pedro Alves Faria ◽  
Ângela Carneiro ◽  
Amândio Rocha-Sousa ◽  
...  
Keyword(s):  
Intravitreal Injection ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Case Series ◽  
Recombinant Tissue Plasminogen Activator ◽  
Submacular Hemorrhage ◽  
Tissue Plasminogen

scholarly journals Intrapericardial recombinant tissue plasminogen activator in purulent pericarditis- case series

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Małgorzata Dybowska ◽  
Monika Szturmowicz ◽  
Lucyna Opoka ◽  
Piotr Rudziński ◽  
Witold Tomkowski
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Case Series ◽  
Recombinant Tissue Plasminogen Activator ◽  
Purulent Pericarditis ◽  
Tissue Plasminogen

MANAGEMENT OF SUBMACULAR HEMORRHAGE WITH INTRAVITREAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR AND EXPANSILE GAS

Retina ◽  
2007 ◽  
Vol 27 (3) ◽  
pp. 321-328 ◽  
Author(s):  
CHRISTINE Y. CHEN ◽  
CLAIRE HOOPER ◽  
DANIEL CHIU ◽  
MATTHEW CHAMBERLAIN ◽  
NIRAL KARIA ◽  
...  
Keyword(s):  
Intravitreal Injection ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Submacular Hemorrhage ◽  
Tissue Plasminogen

Efficacy and safety of recombinant tissue plasminogen activator for venous thrombosis after paediatric heart surgery

2017 ◽  
Vol 28 (2) ◽  
pp. 214-221 ◽  
Author(s):  
Lindsey B. Justice ◽  
David P. Nelson ◽  
Joseph Palumbo ◽  
Jaclyn Sawyer ◽  
Manish N. Patel ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Venous Thrombosis ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Heart Surgery ◽  
Case Series ◽  
Recombinant Tissue Plasminogen Activator ◽  
High Risk Population ◽  
Young Infants ◽  
Tissue Plasminogen

AbstractObjectiveReports in the literature of treatment with recombinant tissue plasminogen activator following cardiac surgery are limited. We reviewed our experience to provide a case series of the therapeutic use of tissue plasminogen activator for the treatment of venous thrombosis in children after cardiac surgery. The data describe the morbidity, mortality, and clinical outcomes of tissue plasminogen activator administration for treatment of venous thrombosis in children following cardiac surgery.DesignThe study was designed as a retrospective case series.SettingThe study was carried out in a 25-bed cardiac intensive care unit in an academic, free-standing paediatric hospital.PatientsAll children who received tissue plasminogen activator for venous thrombosis within 60 days of cardiac surgery, a total of 13 patients, were included.InterventionsData was collected, collated, and analysed as a part of the interventions of this study.Measurements and main resultsPatients treated with tissue plasminogen activator were principally young infants (median 0.2, IQR 0.07–0.58 years) who had recently (22, IQR 12.5–27.3 days) undergone cardiac surgery. Hospital mortality was high in this patient group (38%), but there was no mortality attributable to tissue plasminogen activator administration, occurring within <72 hours. There was one major haemorrhagic complication that may be attributable to tissue plasminogen activator. Complete or partial resolution of venous thrombosis was confirmed using imaging in 10 of 13 patients (77%), and tissue plasminogen activator administration was associated with resolution of chylous drainage, with no drainage through chest tubes, at 10 days after tissue plasminogen activator treatment in seven of nine patients who had upper-compartment venous thrombosis-associated chylothorax.ConclusionsOn the basis of our experience with administration of tissue plasminogen activator in children after cardiac surgery, tissue plasminogen activator is both safe and effective for resolution of venous thrombosis in this high-risk population.

scholarly journals Use of recombinant tissue plasminogen activator for treatment of recalcitrant anterior uveitis: A case series

2018 ◽  
Vol 13 (5) ◽  
pp. 483-487 ◽  
Author(s):  
Sylves Patrick ◽  
Chan Hui-Tze ◽  
Wan Hitam Wan-Hazabbah ◽  
Embong Zunaina ◽  
Yaakub Azhany ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Anterior Uveitis ◽  
Case Series ◽  
Recombinant Tissue Plasminogen Activator ◽  
Tissue Plasminogen
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