Oral Propranolol Therapy for Management of Exudative Retinal Detachment from Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome

2013 ◽  
Vol 23 (6) ◽  
pp. 917-919 ◽  
Author(s):  
Raba Thapa ◽  
Carol L. Shields
Keyword(s):  
Retinal Detachment ◽  
Exudative Retinal Detachment ◽  
Choroidal Hemangioma ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome ◽  
Propranolol Therapy ◽  
Oral Propranolol ◽  
Diffuse Choroidal Hemangioma

scholarly journals The Effectiveness of Propranolol in Managing Hemorrhagic Choroidal and Exudative Retinal Detachment following Ahmed Glaucoma Valve Implantation in Sturge-Weber Syndrome: Case Report and Literature Review

2021 ◽  
pp. 859-869
Author(s):  
Raid Alhayaza ◽  
Saud A. Khan ◽  
Valmore A. Semidey ◽  
Ohoud Owaidhah
Keyword(s):  
Retinal Detachment ◽  
Exudative Retinal Detachment ◽  
Choroidal Detachment ◽  
Ahmed Glaucoma Valve ◽  
Weber Syndrome ◽  
Suprachoroidal Hemorrhage ◽  
Sturge Weber Syndrome ◽  
Valve Implantation ◽  
Ahmed Glaucoma Valve Implantation ◽  
Oral Propranolol

Sturge-Weber syndrome (SWS) is a congenital neurological disorder that is characterized by hamartomas involving the skin, brain, and eyes and marked by the presence of the facial port-wine stain, which consequently leads to various ocular complications. Among all ocular comorbidities, glaucoma is the most frequently witnessed in SWS patients with a prevalence of 30%–70%. If glaucoma is refractory to conventional medical management, surgical intervention can be considered. Common complications of glaucoma procedures in SWS are choroidal detachment and suprachoroidal hemorrhage. Moreover, we report a 6-year-old girl, known case of unilateral congenital glaucoma secondary to SWS. Despite being on maximal antiglaucoma drops and undergoing multiple surgical interventions, the patient had uncontrolled intraocular pressure of her right eye. A decision to proceed with Ahmed glaucoma valve implantation (AGVI) to the right eye was made. In the immediate postoperative period, the patient developed hemorrhagic choroidal detachment and exudative retinal detachment. A trial of oral propranolol (1.5–2 mg/kg/day) was then initiated for 4 months. After 30 days from oral propranolol course initiation, we started noticing a significant improvement of the hemorrhagic choroidal and exudative retinal detachment. Spontaneously, a marked reduction in subretinal fluid and suprachoroidal hemorrhage was also seen. Thus, the improvement was correlated with the propranolol therapy. Here, we report a significant improvement of the postoperative complications of AGVI in a patient with SWS, following 4 months of oral propranolol course (1.5–2 mg/kg/day). Further studies are needed to determine the dosage, duration, and optimal mechanism by which propranolol works in this situation.

Partial thickness sclerectomy to treat exudative retinal detachment secondary a submacular choroidal hemangioma in a Sturge–Weber syndrome

2018 ◽  
Vol 39 (2) ◽  
pp. 491-495
Author(s):  
Barbara Parolini ◽  
Daniele Cardillo ◽  
Andrea Baldi ◽  
Attilio Di Salvatore ◽  
Alessandro Finzi ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Exudative Retinal Detachment ◽  
Choroidal Hemangioma ◽  
Partial Thickness ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome

scholarly journals Ruthenium-106 Plaque Therapy for Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Agnieszka Kubicka-Trząska ◽  
Joanna Kobylarz ◽  
Bożena Romanowska-Dixon
Keyword(s):  
Retinal Detachment ◽  
External Beam Radiotherapy ◽  
Tumor Thickness ◽  
Exudative Retinal Detachment ◽  
Therapy Outcomes ◽  
Corrected Visual Acuity ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome ◽  
Diffuse Choroidal Hemangioma

Diffuse choroidal hemangiomas associated with Sturge-Weber syndrome (SWS) are classically treated with external beam radiotherapy (EBR), but there are a few reports usually of single cases indicating the usefulness of plaque therapy. We present our observations on two cases of diffuse choroidal hemangiomas with exudative retinal detachment associated with SWS treated with Ruthenium-106 plaque therapy. Outcomes included best-corrected visual acuity (BCVA) and regression in tumor thickness measured by ultrasonography. The initial BCVA of the affected eyes was counting fingers at 1 meter and light projection. Pretreatment tumors thickness was 3.5 mm and 4.7 mm. In a follow-up period of 18–24 months, significant reduction in thickness of choroidal hemangiomas up to 1.2 mm and 1.4 mm with prompt resolution of exudative retinal detachment was observed. BCVA achieved 20/200 and 20/400, respectively. The findings in this paper indicate that Ruthenium-106 plaque therapy is effective in treatment of diffuse choroidal hemangiomas associated with SWS.

scholarly journals Photodynamic Therapy for Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Sílvia Monteiro ◽  
Inês Casal ◽  
Marinho Santos ◽  
Angelina Meireles
Keyword(s):  
Visual Acuity ◽  
Photodynamic Therapy ◽  
Therapeutic Option ◽  
Subretinal Fluid ◽  
Exudative Retinal Detachment ◽  
Choroidal Hemangioma ◽  
Weber Syndrome ◽  
Effective Therapeutic Option ◽  
Sturge Weber Syndrome ◽  
Diffuse Choroidal Hemangioma

Purpose.To report the treatment outcome of photodynamic therapy with verteporfin (PDT) for exudative retinal detachment (RD) associated with diffuse choroidal hemangioma in Sturge-Weber syndrome (SWS).Methods.An interventional case report of a 10-year-old girl with SWS who developed an exudative RD (visual acuity hand motions) that was treated with PDT. She was treated with a first session of multispot PDT. Posteriorly, a choroidotomy for drainage of subretinal fluid was created, combined with an intravitreal injection of gas (SF6) and cryoapplication. Finally, a second session of PDT was applied.Results.Subretinal fluid resolved over a period of one year and visual acuity increased to 20/125.Conclusions.PDT is an effective therapeutic option for exudative RD associated with diffuse choroidal hemangioma.

Intractable Choroidal Effusion With Exudative Retinal Detachment in Sturge-Weber Syndrome

2014 ◽  
Vol 132 (9) ◽  
pp. 1143 ◽  
Author(s):  
Sushmita Kaushik ◽  
Savleen Kaur ◽  
Surinder Singh Pandav ◽  
Amod Gupta
Keyword(s):  
Retinal Detachment ◽  
Exudative Retinal Detachment ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome ◽  
Choroidal Effusion

Management of diffuse choroidal hemangioma in Sturge-Weber syndrome with Ruthenium-106 plaque radiotherapy

2015 ◽  
Vol 253 (11) ◽  
pp. 2015-2019 ◽  
Author(s):  
Agnieszka Kubicka-Trząska ◽  
Izabella Karska-Basta ◽  
Piotr Oleksy ◽  
Bożena Romanowska-Dixon
Keyword(s):  
Choroidal Hemangioma ◽  
Weber Syndrome ◽  
Plaque Radiotherapy ◽  
Sturge Weber Syndrome ◽  
Diffuse Choroidal Hemangioma

scholarly journals Effect of acetazolamide for exudative retinal detachment in Sturge-Weber syndrome

2021 ◽  
Vol 2 (9) ◽  
pp. e0129
Author(s):  
Rina Kinouchi ◽  
Hideaki Okumichi ◽  
Hajime Sakata ◽  
Hiromi Ohara ◽  
Kazuyuki Hirooka ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Exudative Retinal Detachment ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome

PHOTODYNAMIC THERAPY USING VERTEPORFIN FOR A DIFFUSE CHOROIDAL HEMANGIOMA IN STURGE–WEBER SYNDROME

Retina ◽  
2004 ◽  
Vol 24 (1) ◽  
pp. 152-155 ◽  
Author(s):  
HARSHIVINDERJIT S. BAINS ◽  
ANTHONY C. CIRINO ◽  
BENJAMIN H. TICHO ◽  
LEE M. JAMPOL
Keyword(s):  
Photodynamic Therapy ◽  
Choroidal Hemangioma ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome ◽  
Diffuse Choroidal Hemangioma
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