Combined Intravitreal Bevacizumab and Grid Laser Photocoagulation for Macular Edema Secondary to Branch Retinal Vein Occlusion

2012 ◽  
Vol 22 (4) ◽  
pp. 607-614 ◽  
Author(s):  
Simone Donati ◽  
Paolo Barosi ◽  
Marco Bianchi ◽  
Muna Al Oum ◽  
Claudio Azzolini
2011 ◽  
Vol 21 (4) ◽  
pp. 434-439 ◽  
Author(s):  
Angel Salinas-Alamán ◽  
Javier Zarranz-Ventura ◽  
Jose M. Caire González-Jauregui ◽  
Luis M. Sádaba-Echarri ◽  
Jesús Barrio-Barrio ◽  
...  

2019 ◽  
Vol 30 (2) ◽  
pp. 370-375
Author(s):  
Seoung Hyun An ◽  
Woo Jin Jeong

Purpose: To investigate the effect of early-scatter laser photocoagulation on the formation of collateral vessels in branch retinal vein occlusion. Methods: The medical records of 40 cases (40 patients) of branch retinal vein occlusion with macular edema were retrospectively reviewed. Of them, 23 patients were treated with intravitreal bevacizumab injection and 17 patients underwent intravitreal bevacizumab injection with additional laser treatment. Early-scatter laser photocoagulation was applied for capillary non-perfusion areas, regardless of retinal neovascularization. Collateral vessel presence, recurrence rate of macular edema, and number of intravitreal bevacizumab injections were compared between the groups. Results: During the follow-up period, collateral vessel formation was noted in 10/23 eyes (43.5%) in the intravitreal bevacizumab injection group and 15/17 eyes (88.2%) in the laser combined treatment group ( p = 0.004). The recurrence rate of macular edema was lower in the laser combined treatment group (29.4%) than in the intravitreal bevacizumab injection group (65.2%); this difference was statistically significant ( p = 0.025). The average numbers of intravitreal bevacizumab injections were 3.57 ± 3.23 in the intravitreal bevacizumab group and 2.14 ± 2.26 in the laser combined treatment group ( p = 0.044). Conclusion: Early-scatter laser photocoagulation promotes collateral vessel formation; the presence of collateral vessels seemed to affect the course of macular edema in branch retinal vein occlusion. Combined early-scatter laser photocoagulation treatment after intravitreal bevacizumab injection lowered the recurrence rate of macular edema and number of intravitreal bevacizumab injections in the cases of branch retinal vein occlusion.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Takafumi Hirashima ◽  
Tomoyuki Chihara ◽  
Toshitaka Bun ◽  
Takao Utsumi ◽  
Miou Hirose ◽  
...  

Background. To evaluate the efficacy of intravitreal bevacizumab (IVB) injection with or without macular laser photocoagulation (MLP) for recurrent or persistent macular edema (ME) secondary to branch retinal vein occlusion (BRVO).Methods. Thirty-four eyes underwent IVB injection for ME secondary to BRVO as a primary treatment. Twenty of the 34 eyes experienced recurrent or persistent ME after the first IVB. Nine of the 20 eyes (Group 1) were retreated with IVB combined with MLP. The remaining 11 eyes (Group 2) were retreated with IVB alone.Results. In Group 1, the postoperative best corrected visual acuity (BCVA) improved compared with the preoperative value at all follow-up visits, although no statistically significant improvement was observed at 6 months. In contrast, BCVA significantly improved from 0.53 to 0.40 at 6 months (P<0.05) in Group 2.Conclusion. Combined therapy tended to have a smaller effect on visual acuity compared with IVB monotherapy.


2009 ◽  
Vol 44 (2) ◽  
pp. 154-159 ◽  
Author(s):  
Amir Ali Ahmadi ◽  
Jean Y. Chuo ◽  
Alexander Banashkevich ◽  
Patrick E. Ma ◽  
David A.L. Maberley

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