scholarly journals Ovarian Hyperstimulation Syndrome on the Acute Medical Unit: A problem-based review

2015 ◽  
Vol 14 (1) ◽  
pp. 21-27
Author(s):  
Rebeca Carter ◽  
◽  
Kyle Petrie ◽  
Ashkan Sadighi ◽  
Hannah Skene ◽  
...  
Keyword(s):  
Ovarian Hyperstimulation Syndrome ◽  
Signs And Symptoms ◽  
In Vitro Fertilisation ◽  
Ovarian Hyperstimulation ◽  
Care Services ◽  
Acute Medical Unit ◽  
Life Threatening ◽  
Acute Care Services ◽  
The Uk

Ovarian Hyperstimulation Syndrome (OHSS) is a spectrum of clinical features typically resulting from assisted conception techniques. With 2.35% of all live births in the UK resulting from in-vitro fertilisation (IVF), OHSS is on the rise. Moreover, there has been an increase in the presentation of its complications to GP surgeries and unscheduled acute care services nationwide. This review will discuss signs and symptoms of the increasingly common and potentially fatal complications of OHSS, namely pleural effusion, ascites and thromboembolic events. With such propensity toward critical, life-threatening events it is not only prudent to recognise the population at risk, but also to be aware of the signs, symptoms and complications to expedite treatment and ensure optimum outcome.

scholarly journals A Case of Isolated Hemorrhagic Pleural Effusion: A Rare Presentation of Ovarian Hyperstimulation Syndrome (OHSS) – A Case Report

2020 ◽  
pp. 23-24
Author(s):  
Sailaja Kambhampati ◽  
M C V Sreekar
Keyword(s):  
Ovarian Hyperstimulation Syndrome ◽  
Fatal Case ◽  
In Vitro Fertilisation ◽  
Ovarian Hyperstimulation ◽  
Pleural Effusions ◽  
Rare Presentation ◽  
Hemorrhagic Pleural Effusion ◽  
Life Threatening

Introduction: Ovarian hyperstimulation syndrome (OHSS) is a rare,life-threatening serious complication of ovulation induction with human chorionic gonadotropin (hCG). (4) 3% of patients undergoing IVF (in vitro fertilisation) develop OHSS. But radiologically evident pleural effusions develop only in 1% among which hemorrhagic effusions are very rare (1). Pleural effusions due to OHSS are usually associated with ascites. Isolated unilateral pleural effusions are uncommon. (2,3) The syndrome occurs in the luteal phase or during early part of pregnancy. The syndrome was first described in 1941 and the first fatal case of OHSS with renal failure and death was described in 1951.

Fatal ovarian hyperstimulation syndrome in an anonymous egg donor

2016 ◽  
Vol 84 (4) ◽  
pp. 219-223 ◽  
Author(s):  
Shashank Pooniya ◽  
C Behera ◽  
AR Mridha ◽  
DN Bhardwaj ◽  
Tabin Millo
Keyword(s):  
Ovarian Hyperstimulation Syndrome ◽  
Ovarian Hyperstimulation ◽  
Medical Negligence ◽  
Assisted Reproduction Techniques ◽  
Vitro Fertilization ◽  
Egg Donor ◽  
Legal Literature ◽  
Life Threatening ◽  
Iatrogenic Disorder

Ovarian hyperstimulation syndrome is a rare, but potentially life-threatening iatrogenic disorder arising from ovulation induction or ovarian hyperstimulation for assisted reproduction techniques. We report a case of a 26-year-old multiparous woman, an anonymous egg donor, who died a few hours after undergoing a procedure to donate eggs at an in vitro fertilization clinic. Her husband alleged that medical negligence had led to her death. The autopsy confirmed death due to ovarian hyperstimulation syndrome. We know of no previous descriptions of fatal ovarian hyperstimulation syndrome in an anonymous egg donor in medico-legal literature.

Ovarian hyperstimulation syndrome: cardiac arrest with an unexpected outcome

2021 ◽  
Vol 14 (11) ◽  
pp. e246780
Author(s):  
Jonathan Gaughran ◽  
Tom Lyne ◽  
Julia Kopeika ◽  
Judith Hamilton
Keyword(s):  
Pulmonary Embolism ◽  
Cardiac Arrest ◽  
Ovarian Hyperstimulation Syndrome ◽  
Late Onset ◽  
Massive Pulmonary Embolism ◽  
Full Recovery ◽  
In Vitro Fertilisation ◽  
Ovarian Hyperstimulation ◽  
Unexpected Outcome

We describe the acute deterioration of a 29-year-old undergoing in vitro fertilisation. Late-onset critical ovarian hyperstimulation syndrome triggered a massive pulmonary embolism and subsequent cardiac arrest. While the prognosis was deemed to be poor, the patient made a full recovery. The potential reasons for this are explored.

scholarly journals A rare presentation of endogenous human chorionic gonadotrophin associated severe ovarian hyperstimulation in the second trimester: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Abraham Fessehaye ◽  
Wondimu Gudu
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Ovarian Hyperstimulation Syndrome ◽  
Multiple Pregnancy ◽  
Intensive Care Unit Care ◽  
Ovarian Hyperstimulation ◽  
Triplet Pregnancy ◽  
Rare Presentation ◽  
Life Threatening

Abstract Background Ovarian hyperstimulation syndrome is usually an iatrogenic and potentially life-threatening disease. It develops following ovulation induction and use of in vitro fertilization techniques. Case summary A 32-year-old primigravida Ethiopian woman presented at 15 weeks gestation with a history of progressive bilateral leg swelling and abdominal pain of 2 weeks duration. She had triplet pregnancy and conceived through in vitro fertilization. She was managed in intensive care unit. Conclusion Patients with multiple pregnancy following in vitro fertilization conception can have ovarian hyperstimulation syndrome as late as 15 weeks gestation. Hence, frequent follow-up should be continued to detect early signs of OHSS to avoid further complications and need of intensive care unit care.

scholarly journals Ovarian Hyperstimulation Syndrome Ratio And In Vitro Fertilization Success With Gonadotrphine Releasing Hormone Trigger And 1500 IU Human Chorionic Gonadotrophine For Luteal Support

2018 ◽  
Vol 2 (1) ◽  
Keyword(s):  
At Risk ◽  
Pregnancy Rate ◽  
Ovarian Hyperstimulation Syndrome ◽  
Trigger Factor ◽  
In Vitro Fertilisation ◽  
Ovarian Hyperstimulation ◽  
Luteal Support ◽  
Releasing Hormone ◽  
Patients At Risk

Intraduction: Ovarian hyperstimulation syndrome (OHSS) is very serius complication of in vitro fertilisation (IVF) treatments. Human chorionic gonadotrophine (hCG) is the trigger factor of the syndrome. Gonadotrophine releasing hormone agonist (GnRHa) can use instead of hCG for triggering the ovulation. Matherial and Methods: This study aims to evaluate the effects of ovulation triggering with Gonadotrophine Releasing Hormone Agonists (GnRHa) on ovarian hyperstimulation syndrome (OHSS) rates and pregnancy success in patients at risk of OHSS. 51 cycles were evaluated in 50 women. Gonadotrophine (Gn) was applied to all patients with a flexible GnRHa protocol. To trigger ovulation, 0.2 mg triptorelin was applied when the estradiol level was 3500-7000 pg/mL and/or when at least 18 follicles were determined at ≥10mm. Oocyte Pick-Up (OPU) was performed 35 hours after the triptorelin injection. Within 1 hour of OPU, luteal support with 1500 IU hCG was administered to the patients and on the night of OPU, vaginal progesterone and oral estrogen were started. Results: OHSS was determined in 5 cycles (9.8%), and 4 of them (7.8%) were early OHSS. Embryo transfer was applied in 49 cycles. The pregnancy rate was determined as 44.9%, clinical pregnancy rate as 26.5%, continuing pregnancy rate as 24.4% and the abortus rate as 2%. Conclusion: GnRHa triggering applied before treatment to patients at risk of early OHSS does not completely eliminate the risk of OHSS. Nevertheless, this protocol improved treatment results without increasing the rates of severe OHSS.

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