scholarly journals Liver transplantation in Wilson's disease: A systematic review

2021 ◽  
Author(s):  
Emre Turgut ◽  
Cemalettin Aydin ◽  
Cuneyt Kayaalp ◽  
Sezai Yilmaz
Keyword(s):  
Systematic Review ◽  
Liver Transplantation ◽  
Wilson’S Disease ◽  
Wilson's Disease

Liver Transplantation for Wilson's Disease in Non-adult Patients: A Systematic Review

2019 ◽  
Vol 51 (2) ◽  
pp. 443-445 ◽  
Author(s):  
Z. Garoufalia ◽  
A. Prodromidou ◽  
N. Machairas ◽  
I.D. Kostakis ◽  
P. Stamopoulos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Transplantation ◽  
Wilson’S Disease ◽  
Wilson's Disease ◽  
Adult Patients

The Need for Consensus About Liver Transplantation For Patients With Neuropsychiatric Wilson’s Disease

2021 ◽  
pp. 152692482110028
Author(s):  
Alberto Ferrarese ◽  
Patrizia Burra
Keyword(s):  
Liver Transplantation ◽  
Patient Outcomes ◽  
Wilson’S Disease ◽  
Therapeutic Option ◽  
Copper Metabolism ◽  
Wilson's Disease ◽  
Published Data ◽  
Neurological Improvement ◽  
Effective Therapeutic Option

Liver transplantation is considered an effective therapeutic option for Wilson’s disease (WD) patients with hepatic phenotype, since it removes the inherited defects of copper metabolism, and is associated with excellent graft and patient outcomes. The role of liver transplantation in WD patients with mixed hepatic and neuropsychiatric phenotype has remained controversial over time, mainly because of high post-operative complications, reduced survival and a variable, unpredictable rate of neurological improvement. This article critically discusses the recently published data in this field, focussing in more detail on isolated neuropsychiatric phenotype as a potential indication for liver transplantation in WD patients.

scholarly journals Parkinson’s Disease and Metal Storage Disorders: A Systematic Review

2018 ◽  
Vol 8 (11) ◽  
pp. 194 ◽  
Author(s):  
Edward Botsford ◽  
Jayan George ◽  
Ellen Buckley
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Wilson’S Disease ◽  
Case Reports ◽  
Hereditary Hemochromatosis ◽  
Wilson's Disease ◽  
Neurological Dysfunction ◽  
Cross Sectional ◽  
Storage Disorders

Metal storage disorders (MSDs) are a set of rare inherited conditions with variable clinical pictures including neurological dysfunction. The objective of this study was, through a systematic review, to identify the prevalence of Parkinsonism in patients with MSDs in order to uncover novel pathways implemented in Parkinson’s disease. Human studies describing patients of any age with an MSD diagnosis were analysed. Foreign language publications as well as animal and cellular studies were excluded. Searches were conducted through PubMed and Ovid between April and September 2018. A total of 53 publications were identified including 43 case reports, nine cross-sectional studies, and one cohort study. The publication year ranged from 1981 to 2018. The most frequently identified MSDs were Pantothenate kinase-associated neurodegeneration (PKAN) with 11 papers describing Parkinsonism, Hereditary hemochromatosis (HH) (7 papers), and Wilson’s disease (6 papers). The mean ages of onset of Parkinsonism for these MSDs were 33, 53, and 48 years old, respectively. The Parkinsonian features described in the PKAN and HH patients were invariably atypical while the majority (4/6) of the Wilson’s disease papers had a typical picture. This paper has highlighted a relationship between MSDs and Parkinsonism. However, due to the low-level evidence identified, further research is required to better define what the relationship is.

scholarly journals Biochemical testing for the diagnosis of Wilson's disease: A systematic review

2021 ◽  
Author(s):  
Hafiz Muhammad Salman ◽  
Mahwish Amin ◽  
Javaria Syed ◽  
Zouina Sarfraz ◽  
Azza Sarfraz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Wilson’S Disease ◽  
Wilson's Disease ◽  
Biochemical Testing

Liver transplantation for fulminant Wilson's disease, the significance of prothrombin time on admission

2000 ◽  
Vol 118 (4) ◽  
pp. A1495
Author(s):  
Pavel Trunecka ◽  
Miroslav Ryska ◽  
Jan Sperl ◽  
Lubomir Kozak ◽  
Milan Jirsa ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prothrombin Time ◽  
Wilson’S Disease ◽  
Wilson's Disease

Successful treatment of fulminant Wilson's disease without liver transplantation

2014 ◽  
Vol 56 (3) ◽  
pp. 429-432 ◽  
Author(s):  
Mitsuo Motobayashi ◽  
Tetsuhiro Fukuyama ◽  
Yoshiko Nakayama ◽  
Kenji Sano ◽  
Shunsuke Noda ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Successful Treatment ◽  
Wilson’S Disease ◽  
Wilson's Disease

Cerebral manifestation of Wilson's disease successfully treated with liver transplantation

Neurology ◽  
1998 ◽  
Vol 51 (3) ◽  
pp. 863-865 ◽  
Author(s):  
R. T. Bax ◽  
A. Hassler ◽  
W. Luck ◽  
H. Hefter ◽  
I. Krageloh-Mann ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Wilson’S Disease ◽  
Wilson's Disease

Differential expression of proteins associated with liver transplantation in wilson’s disease patients

1998 ◽  
Vol 30 (7) ◽  
pp. 3263-3264
Author(s):  
K.C Chiang ◽  
T.L Pan ◽  
S Goto ◽  
Y.C Lin ◽  
C.Y Lai ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Differential Expression ◽  
Wilson’S Disease ◽  
Wilson's Disease
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