Paper-Based Analytical Device for Rapid Naked-Eye Detection of Sulfide in Water Samples

2020 ◽  
Vol 42 (5) ◽  
pp. 696-696
Author(s):  
Lingzhi Zhao Lingzhi Zhao
Keyword(s):  
Water Samples ◽  
Limit Of Detection ◽  
Rapid Determination ◽  
Tap Water ◽  
Low Cost ◽  
Color Intensity ◽  
Detection Zone ◽  
Simulated Waste ◽  
Optimized Conditions ◽  
Analytical Device

This paper describes the development of a low-cost paper-based colorimetric analytical device for the accurate and rapid determination of sulfide. Under optimized conditions, Na2S was dropped in the uptake zone I and the probe in the uptake zone II, they converged to the detection zone via capillary force and formed an intense pink resorufin. Sulfide can be quantified based on the average color intensity values of the product “free resorufin”. The color intensity is recorded using a camera phone, and quantification was made using Adobe Photoshop. The as-developed analytical device detected sulfide in the range of 5–400 μM (R2 = 0.982) with the limit of detection (LOD) 1 μM, and was successfully applied in sulfide assay in spiked water samples including tap water and simulated waste water. Colorimetric results from the proposed paper-based colorimetric analytical device were consistent with that from methylene blue (MB) method.

scholarly journals Dual-Modal Assay Kit for the Qualitative and Quantitative Determination of the Total Water Hardness Using a Permanent Marker Fabricated Microfluidic Paper-Based Analytical Device

Chemosensors ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 97
Author(s):  
Oyejide Damilola Oyewunmi ◽  
Seyed Hamid Safiabadi-Tali ◽  
Sana Jahanshahi-Anbuhi
Keyword(s):  
Ethylenediaminetetraacetic Acid ◽  
Limit Of Detection ◽  
Low Cost ◽  
Water Hardness ◽  
Sample Introduction ◽  
World Health ◽  
Total Hardness ◽  
Quantitative Detection ◽  
Qualitative And Quantitative ◽  
Analytical Device

A dip-and-read microfluidic paper-based analytical device (µPAD) was developed for the qualitative and quantitative detection of the total hardness of water. To create well-defined hydrophobic barriers on filter paper, a regular office printer and a commercially available permanent marker pen were utilized as a quick and simple technique with easily accessible equipment/materials to fabricate µPAD in new or resource-limited laboratories without sophisticated equipment. After a wettability and barrier efficiency analysis on the permanent marker colors, the blue and green ink markers exhibited favorable hydrophobic properties and were utilized in the fabrication of the developed test devices. The device had five reaction and detection zones modeled after the classification given by the World Health Organization (WHO), so qualitatively it determined whether the water was ‘soft’, ‘moderately hard’, ‘hard’, or ‘very hard’ by changing color from blue to pink in about 3 min. The device was also used to introduce an alternative colorimetric reaction for quantitative analysis of the water hardness without the need for ethylenediaminetetraacetic acid (EDTA) and without compromising the simplicity and low cost of the device. The developed µPAD showed a calculated limit of detection (LOD) of 0.02 mM, which is at least 80% less than those of commercially available test strips and other reported µPADs, and the results of the real-world samples were consistent with those of the standard titration (with EDTA). In addition, the device exhibited stability for 2 months at room and frigid condition (4 °C) and at varying harsh temperatures from 25 to 100 °C. The results demonstrate that the developed paper-based device can be used for rapid, on-site analysis of water with no interferences and no need for a pipette for sample introduction during testing.

scholarly journals Highly Selective, Aptamer-Based, Ultrasensitive Nanogold Colorimetric Smartphone Readout for Detection of Cd(II)

Molecules ◽  
2019 ◽  
Vol 24 (15) ◽  
pp. 2745 ◽  
Author(s):  
Lu Xu ◽  
Jun Liang ◽  
Yonghui Wang ◽  
Shuyue Ren ◽  
Jin Wu ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Low Cost ◽  
Quantitative Detection ◽  
Practical Application ◽  
Full Agreement ◽  
Experimental Conditions ◽  
Dose Time ◽  
Dimethyl Ammonium ◽  
Rice Samples ◽  
Optimized Conditions

A highly selective and sensitive method for Cd(II) detection was developed based on aptamer and gold nanoparticles (AuNPs) combined with a colorimetric smartphone readout. The experimental conditions such as reaction time of polydiene dimethyl ammonium chloride (PDDA) and AuNPs, PDDA dose, time of aptamer and PDDA incubation, and aptamer concentration were optimized. Under the optimized conditions, the color and red(R) value of the solution was concentration-dependent on Cd(II). The proposed method exhibited a linear range of 1–400 ng/mL (r2 = 0.9794) with a limit of detection (LOD) of 1 ng/mL. This method had been successfully applied to test and quantify Cd(II) in water and rice samples, and the results were in full agreement with those from the atomic absorption spectrometer. Therefore, low-cost colorimetry demonstrated its potential for practical application in visual or quantitative detection with a smartphone. This approach can be readily applied to other analytes.

Determination of Phthalate Acid Esters in Water and Sediment Samples by GC–MS

2012 ◽  
Vol 610-613 ◽  
pp. 157-162 ◽  
Author(s):  
Xiao Ling Shao ◽  
Yan Min Zou ◽  
Fu Xing Wang ◽  
Zhen Zhang ◽  
Song Mei Wang ◽  
...  
Keyword(s):  
Water Samples ◽  
Yangtze River ◽  
Limit Of Detection ◽  
Solid Phase ◽  
Tap Water ◽  
Gas Chromatography Mass Spectrometry ◽  
Sediment Samples ◽  
Pollution Levels ◽  
Acid Esters ◽  
Phthalate Acid Esters

Water and bottom sediment samples were taken from the Zhenjiang section of the lower reach of Yangtze River, China during the autumn of 2011, aimed to study the pollution levels of six kinds of phthalate acid esters (PAEs). Water samples were prepared by solid-phase extraction (SPE) and analyzed by gas chromatography-mass spectrometry (GC–MS), with spiked recoveries ranging from 33.5% to 121.0%. Sediment samples were pretreated using ultrasonic-assisted organic solvent extraction, with recoveries varying from 43.7% to 107.6%. Results showed that the concentration levels of PAEs are below the limit of detection (LOD) –63.3μg/L in the water samples of Yangtze River. Tongji River water are severely contaminated by PAEs, with the concentrations of di-n-butyl phthalate (DnBP) up to 613ug/L. Four of PAEs were detected in the tap water of Zhenjiang. It was also found that all of detected PAEs are dominantly partitioned on suspended solids in water samples. The concentrations of PAEs in sediment samples are ranged from <LOD to 7.5mg/kg.

Time-resolved quenched phosphorescence detection of chromate in water samples using paired-ion reversed phase high performance liquid chromatography

1987 ◽  
Vol 65 (5) ◽  
pp. 965-969 ◽  
Author(s):  
Robert A. Baumann ◽  
Marry Schreurs ◽  
Cees Gooijer ◽  
Nel H. Velthorst ◽  
Roland W. Frei
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Water Samples ◽  
High Performance ◽  
Limit Of Detection ◽  
Tap Water ◽  
Reversed Phase ◽  
Time Resolved ◽  
Potential Applicability ◽  
Surface Water Samples

The feasibility of time-resolved quenched phosphorescence as a detection method for chromate based on paired-ion reversed phase high performance liquid chromatography is shown. After separation detection is achieved by monitoring the time-resolved phosphorescence signal of biacetyl at 515 nm. Optimization of the time-resolution parameters of the luminescence detector results in a limit of detection of 1.4 × 10−7 M (2 ng on column) for chromate standard solutions. The linearity of the method is three orders of magnitude. Chromatograms of tap water and surface water samples spiked with chromate show the potential applicability of the method for real samples.

scholarly journals Lead Ions Removal from Natural Water Samples by Nano-Mint Waste as Benign Low Cost Biosorbent

2018 ◽  
Vol 3 (2) ◽  
pp. 116-126
Author(s):  
Tamer H. A. Hasanin ◽  
Salwa A. Ahmed ◽  
Taghreed B. Ebrahim
Keyword(s):  
Natural Water ◽  
Water Samples ◽  
Metal Ion ◽  
Sea Water ◽  
Tap Water ◽  
Low Cost ◽  
Lead Removal ◽  
Lead Uptake ◽  
Natural Water Samples ◽  
Uptake Process

Nano mint waste (NMW) was used as a low-cost nano biosorbent and efficient Pb(II) remover. pH, contact time, biosorbent dose, and concentration of metal ion were optimized using batch technique to optimize maximum capacity of this new biosorbent. NMW was characterized using FT-IR, SEM, TEM, and XRD analyses. The experimental Pb(II) adsorption data by NMW were agreed with both Freundlich and Langmuir models with maximum boisorption capacity of 2.13 mmolg-1 (441.336 mgg-1). In addition, values of lead uptake at different time vaues was best fitted with the kinetic pseudo-second order model. It will be notable that, good data resulted from the kinetic experiments study confirmed a fast accessibility of the Pb(II) to the biosorbent surface, get to equilibrium within 30 seconds. On the other hand, it was observed that, the developed method, was investigated for measuring of Pb(II) with a certain spiked amounts in natural water samples as ground water (GW), sea water (SW), drinking tap water (DTW), natural drinking water (NDW), Nile River water (NRW) and waste water (WW). The good results obtained with high recovered quantitatively using batch experiments, without matrix interferences. Considering its cheap source, environmentally friendly, economic and fast uptake process, NMW can be used as benign nano biosorbent for lead removal from real water samples.

scholarly journals PENGEMBANGAN METODE CITRA DIGITAL BERBASIS APLIKASI ANDROID UNTUK ANALISIS ION LOGAM Cr(VI)

Alotrop ◽  
2019 ◽  
Vol 2 (2) ◽  
pp. 117-124
Author(s):  
Marti Hitsmi ◽  
Mochamad Lutfi Firdaus ◽  
Nurhamidah Nurhamidah
Keyword(s):  
Metal Ions ◽  
Digital Image ◽  
Water Samples ◽  
Metal Ion ◽  
Limit Of Detection ◽  
Tap Water ◽  
Inductively Couple Plasma ◽  
Image Method ◽  
Complex Method ◽  
Conventional Methods

The presence of heavy metals in the environment can be a serious problem because it is harmful to human health. One of the heavy metal ions that pollute the environment is the Cr6+ metal ion. The usual tool used to analyze metal ions is Cr6+ is the Atomic Absorption Spectrometry (AAS) and Inductively Couple Plasma (ICP) which are very expensive and require trained personnel. The purpose of this study was to design a simple detector for Cr6+ metal ions as an alternative to conventional methods using AAS and ICP. The detection tool was developed using the android-based digital image method with SLR data analysis techniques obtained from the reaction of the metal ion complex Cr6 + with the compound dhypenilcarbazida (DPC). The parameters of the tool measured were accuracy, selectivity and sensitivity with the reaction of DPC compounds as complexes. The comparison level of this method is the complex method with DPC using a UV-Vis spectrophotometer. This research was carried out in the Chemistry Laboratory FKIP UNIB in November 2018 until March 2019. The implementation of tool parameters was tested to samples of aquatic environments in Bengkulu City, namely PDAM Kota Bengkulu water, tap water of FKIP UNIB Dean, Lake UNIB water, Sungai Hitam water and water Pantai Panjang. The results showed that the detection of Cr6+ metal ions made by the android-based digital image method had better accuracy, selectivity and sensitivity than conventional methods. The DPC is selective for Cr6 + metal ions with a change in color from clear to violet, at a wavelength of 540 nm. Accuracy was checked using a UV-Vis spectrophotometer with 99% accurate results. After that, test sensitivity to Cr6 + metal ions. using the android application method generates a Limit of Detection (LOD) of 6.7 ppb. The detector that was developed was applied to water samples in the city of Bengkulu, it turned out that all of the water samples showed that the levels of Cr6+ metal ions were still below the threshold determined by the Minister of Health Regulation, so it was still safe to use in everyday life.

scholarly journals Characterization of handmade Nepali paper as a platform for paper analytical device to determine anti-diabetic drug

2021 ◽  
Author(s):  
Ram Bhattarai ◽  
Sanam Pudasaini ◽  
Mukesh Sah ◽  
Bhanu Neupane ◽  
Basant Giri
Keyword(s):  
Limit Of Detection ◽  
Low Cost ◽  
Water Contact ◽  
Regulatory Standards ◽  
Three Samples ◽  
Limit Of Quantitation ◽  
Metformin Concentration ◽  
Analytical Device

The COVID-19 pandemic has highlighted the need of eco-friendly and locally or distributed manufacturing of diagnostic and safety products. Here, we characterized five handmade papers for their potential application to make paper analytical device (PADs). The handmade papers were made from locally available plant fiber using eco-friendly method. Thickness, grammage, and apparent density of the paper samples ranged from 198 μm to 314 μm, 49 g/m2 to 117.8 g/m2, and 0.23 to 0.39 g/cm3, respectively. Moisture content, water filtration and wicking speed ranged from 5.2% to 7.1%, 35.7 to 156.7, and 0.062 to 0.124 mms-1, respectively. Further, water contact angle and porosity ranged from 76˚ to 112˚ and 79% to 83%, respectively. The best paper sample one was chosen to fabricate PADs which were used for the determination of metformin. The metformin assay on PADs followed linear range from 0.0625 to 0.5 mg/mL. The assay had limit of detection and limit of quantitation of 0.05 mg/mL and 0.18 mg/mL respectively. The new method was used to test metformin samples (n=20) collected from local pharmacies. The average amount of metformin concentration in samples was 465.6 ± 15.1mg/tablet. Three samples did not meet the regulatory standards. When compared with spectrophotometric method, PADs assay correctly predicted 18 out of 20 samples. The PADs assay on handmade paper may provide a low-cost and easy-to-use system to screening the quality of drugs and other point-of-need applications.

scholarly journals A simple AuNPs-based colorimetric aptasensor for chlorpyrifos detection

2021 ◽  
Author(s):  
Yuan Liu ◽  
Taotao Li ◽  
Gaojian Yang ◽  
Yan Deng ◽  
Xianbo Mou ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Tap Water ◽  
Low Cost ◽  
Organophosphorus Pesticide ◽  
Detection Methods ◽  
Label Free ◽  
Human Beings ◽  
Free Gold ◽  
Dissociation Constant Kd ◽  
Colorimetric Aptasensor

Abstract Background Chlorpyrifos (Chl) is an organophosphorus pesticide, which has toxicity to environment, animals and human beings. To overcome the shortages of traditional detection methods of small molecular, this study aimed to develop a sensitive, simple, low cost and on-site rapid method for Chl analysis and detection. Thus, we developed a simple label-free gold nanoparticles (AuNPs) based colorimetric biosensor aptasensor for Chl detection using an aptamer as the caputure probe. Results The Chl-aptamer with low dissociation constant (Kd) of 58.59 ± 6.08 (nM) was selected by ssDNA library immobilized systematic evolution of ligands by enrichment (SELEX). In the absence of Chl, the Chl-aptamer acted as the stabilizer for AuNPs in salt solution. In the presence of Chl, the highly specific Chl-aptamer bound with Chl targets immediately thus a self-aggregation of AuNPs induced by salt was displayed. The fabricated colorimetric aptasensor exhibited an excellent sensitivity for Chl detection with the limit of detection as low as 14.46 nM. In addition, the aptasensor was applied to test Chl in tap water, cucumber and cabbage samples, which showed satisfying results with excellent recovery values between 96.2% and 105.6% and acceptable RSD values below 5%. Conclusions The developed colorimetric aptasensor can serve as a promising candidate for Chl detection in the area of biosensors, which also showed a great potential in simple, cheap and rapid detection of Chl.

scholarly journals Electrochemical micro analytical device interfaced with portable potentiostat for rapid detection of chlorpyrifos using acetylcholinesterase conjugated metal organic framework using Internet of things

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Shalini Nagabooshanam ◽  
Souradeep Roy ◽  
Ashish Mathur ◽  
Irani Mukherjee ◽  
Satheesh Krishnamurthy ◽  
...  
Keyword(s):  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Low Cost ◽  
Metal Organic Framework ◽  
Electrochemical Techniques ◽  
Electrochemical Analysis ◽  
Vegetable Sample ◽  
Metal Organic ◽  
Analytical Device ◽  
Organic Framework

AbstractAn Electrochemical micro Analytical Device (EµAD) was fabricated for sensitive detection of organophosphate pesticide chlorpyrifos in the food chain. Gold microelectrode (µE) modified with Zinc based Metal Organic Framework (MOF-Basolite Z1200) and Acetylcholinesterase (AChE) enzyme served as an excellent electro-analytical transducer for the detection of chlorpyrifos. Electrochemical techniques such as Cyclic Voltammetry (CV), Electrochemical Impedance Spectroscopy (EIS) and Differential Pulse Voltammetry (DPV) were performed for electrochemical analysis of the developed EµAD. The sensor needs only 2 µL of the analyte and it was tested within the linear range of 10 to 100 ng/L. The developed EµAD’s limit of detection (LoD) and sensitivity is 6 ng/L and 0.598 µ A/ng L−1/mm2 respectively. The applicability of the device for the detection of chlorpyrifos from the real vegetable sample was also tested within the range specified. The fabricated sensor showed good stability with a shelf-life of 20 days. The EµAD’s response time is of 50 s, including an incubation time of 20 s. The developed EµAD was also integrated with commercially available low-cost, handheld potentiostat (k-Stat) using Bluetooth and the results were comparable with a standard electrochemical workstation.

scholarly journals Determination of As, Cd, and Pb in Tap Water and Bottled Water Samples by Using Optimized GFAAS System with Pd-Mg and Ni as Matrix Modifiers

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Sezgin Bakırdere ◽  
Tolga Yaroğlu ◽  
Nihan Tırık ◽  
Mehmet Demiröz ◽  
A. Kemal Fidan ◽  
...  
Keyword(s):  
Water Samples ◽  
Tap Water ◽  
Graphite Furnace ◽  
Detection Limits ◽  
Absorption Spectrometry ◽  
Bottled Water ◽  
Matrix Modifier ◽  
Lead And Cadmium ◽  
West Part ◽  
Optimized Conditions

Arsenic, lead, and cadmium were determined in tap and bottled water samples consumed in the west part of Turkey at trace levels. Graphite furnace atomic absorption spectrometry (GFAAS) was used in all detections. All of the system parameters for each element were optimized to increase sensitivity. Pd-Mg mixture was selected as the best matrix modifier for As, while the highest signals were obtained for Pb and Cd in the case of Ni used as matrix modifier. Detection limits for As, Cd, and Pb were found to be 2.0, 0.036, and 0.25 ng/mL, respectively. 78 tap water and 17 different brands of bottled water samples were analyzed for their As, Cd, and Pb contents under the optimized conditions. In all water samples, concentration of cadmium was found to be lower than detection limits. Lead concentration in the samples analyzed varied between N.D. and 12.66 ± 0.68 ng/mL. The highest concentration of arsenic was determined as 11.54 ± 2.79 ng/mL. Accuracy of the methods was verified by using a certified reference material, namely, Trace Element in Water, 1643e. Results found for As, Cd, and Pb in reference materials were in satisfactory agreement with the certified values.

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